Search Results - "M Braga, Vania M"

So far, yet so close: a-Catenin dimers help migrating cells get together by Machesky, Laura, M Braga, Vania M

“…Epithelial cells in tissues use their actin cytoskeletons to stick together, whereas unattached cells make active plasma membrane protrusions to migrate. Here,…”
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L-amino acid oxidase from Bothrops atrox snake venom triggers autophagy, apoptosis and necrosis in normal human keratinocytes by Costal-Oliveira, Fernanda, Stransky, Stephanie, Guerra-Duarte, Clara, Naves de Souza, Dayane L., Vivas-Ruiz, Dan E., Yarlequé, Armando, Sanchez, Eladio Flores, Chávez-Olórtegui, Carlos, Braga, Vania M. M.

“…Snake venom L-amino acid oxidases (LAAOs) are flavoproteins, which perform diverse biological activities in the victim such as edema, myotoxicity and…”
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Intrinsic cell rheology drives junction maturation by Sri-Ranjan, K., Sanchez-Alonso, J. L., Swiatlowska, P., Rothery, S., Novak, P., Gerlach, S., Koeninger, D., Hoffmann, B., Merkel, R., Stevens, M. M., Sun, S. X., Gorelik, J., Braga, Vania M. M.

“…A fundamental property of higher eukaryotes that underpins their evolutionary success is stable cell-cell cohesion. Yet, how intrinsic cell rheology and…”
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Rac1-PAK1 regulation of Rab11 cycling promotes junction destabilization by Erasmus, Jennifer C, Smolarczyk, Kasia, Brezovjakova, Helena, Mohd-Naim, Noor F, Lozano, Encarnación, Matter, Karl, Braga, Vania M M

“…Rac1 GTPase is hyperactivated in tumors and contributes to malignancy. Rac1 disruption of junctions requires its effector PAK1, but the precise mechanisms are…”
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Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus by Jaber, Nadia, Mohd-Naim, Noor, Wang, Ziqing, DeLeon, Jennifer L, Kim, Seong, Zhong, Hua, Sheshadri, Namratha, Dou, Zhixun, Edinger, Aimee L, Du, Guangwei, Braga, Vania M M, Zong, Wei-Xing

“…The class III phosphoinositide 3-kinase (PI3K) Vps34 (also known as PIK3C3 in mammals) produces phosphatidylinositol 3-phosphate [PI(3)P] on both early and…”
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Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1 by Dawson, John C, Bruche, Susann, Spence, Heather J, Braga, Vania M M, Machesky, Laura M

“…Cell-cell junctions are an integral part of epithelia and are often disrupted in cancer cells during epithelial-to-mesenchymal transition (EMT), which is a…”
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Illuminating the functional and structural repertoire of human TBC/RABGAPs by Frasa, Marieke A. M., Koessmeier, Katja T., Ahmadian, M. Reza, Braga, Vania M. M.

“…TBC/RABGAPs are negative regulators of RABs that carry a conserved TBC domain. In addition to their roles in intracellular trafficking, they have recently…”
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Actin at cell-cell junctions is composed of two dynamic and functional populations by Zhang, Juankun, Betson, Martha, Erasmus, Jennifer, Zeikos, Kostas, Bailly, Maryse, Cramer, Louise P, Braga, Vania M M

“…The ability of epithelial cells to polarize requires cell-cell adhesion mediated by cadherin receptors. During cell-cell contact, the mechanism via which a…”
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RhoG is required for both FcγR- and CR3-mediated phagocytosis by Tzircotis, George, Braga, Vania M M, Caron, Emmanuelle

“…Phagocytosis is a highly ordered process orchestrated by signalling through Rho GTPases to locally organise the actin cytoskeleton and drive particle uptake…”
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Ajuba is required for Rac activation and maintenance of E-cadherin adhesion by Nola, Sébastien, Daigaku, Reiko, Smolarczyk, Kasia, Carstens, Maryke, Martin-Martin, Belen, Longmore, Gregory, Bailly, Maryse, Braga, Vania M M

“…Maintenance of stable E-cadherin-dependent adhesion is essential for epithelial function. The small GTPase Rac is activated by initial cadherin clustering, but…”
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PAK is required for the disruption of E-cadherin adhesion by the small GTPase Rac by Lozano, Encarnación, Frasa, Marieke A.M, Smolarczyk, Katarzyna, Knaus, Ulla G, Braga, Vania M.M

“…E-cadherin cell-cell adhesion plays a major role in the maintenance of the morphology and function of epithelial tissues. Modulation of E-cadherin function is…”
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Rap1 Regulates the Formation of E-Cadherin-Based Cell-Cell Contacts by Hogan, Catherine, Serpente, Norberto, Cogram, Patricia, Hosking, Catherine Rose, Bialucha, Carl Uli, Feller, Stephan Michael, Braga, Vania M. M., Birchmeier, Walter, Fujita, Yasuyuki

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The LIM Protein Ajuba Influences p130Cas Localization and Rac1 Activity during Cell Migration by Pratt, Stephen J., Epple, Holly, Ward, Michael, Feng, Yunfeng, Braga, Vania M., Longmore, Gregory D.

“…Cell migration requires extension of lamellipodia that are stabilized by formation of adhesive complexes at the leading edge. Both processes are regulated by…”
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Vascular Permeability: Flow-Mediated, Non-canonical Notch Signalling Promotes Barrier Integrity by Fischer, Andreas, Braga, Vania M.M.

“…The vascular permeability barrier must be maintained in response to changes to vessel calibre, shear stress and blood pressure. A new study reveals a…”
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Cycling around cell-cell adhesion with Rho GTPase regulators by McCormack, Jessica, Welsh, Natalie J, Braga, Vania M M

“…The formation and stability of epithelial adhesive systems, such as adherens junctions, desmosomes and tight junctions, rely on a number of cellular processes…”
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Junction Mapper is a novel computer vision tool to decipher cell-cell contact phenotypes by Brezovjakova, Helena, Tomlinson, Chris, Mohd Naim, Noor, Swiatlowska, Pamela, Erasmus, Jennifer C, Huveneers, Stephan, Gorelik, Julia, Bruche, Susann, Braga, Vania Mm

“…Stable cell-cell contacts underpin tissue architecture and organization. Quantification of junctions of mammalian epithelia requires laborious manual…”
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miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts by Pellegrino, Loredana, Stebbing, Justin, Braga, Vania M, Frampton, Adam E, Jacob, Jimmy, Buluwela, Lakjaya, Jiao, Long R, Periyasamy, Manikandan, Madsen, Chris D, Caley, Matthew P, Ottaviani, Silvia, Roca-Alonso, Laura, El-Bahrawy, Mona, Coombes, R Charles, Krell, Jonathan, Castellano, Leandro

“…Uncontrolled cell proliferation and cytoskeletal remodeling are responsible for tumor development and ultimately metastasis. A number of studies have…”
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So far, yet so close: α-Catenin dimers help migrating cells get together by Machesky, Laura, Braga, Vania M M

“…Epithelial cells in tissues use their actin cytoskeletons to stick together, whereas unattached cells make active plasma membrane protrusions to migrate. In…”
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Bothrops atrox venom: Biochemical properties and cellular phenotypes of three highly toxic classes of toxins by Lopes-de-Souza, Leticia, Costal-Oliveira, Fernanda, Rodrigues, Carolina Rego, Stransky, Stephanie, de Assis, Thamyres C.S., Liberato, Camila, Vivas-Ruiz, Dan, Chocas, Armando Yarleque, Guerra-Duarte, Clara, Braga, Vania M.M., Chávez-Olortegui, Carlos

“…Snake venoms have a complex mixture of compounds that are conserved across species and act synergistically, triggering severe local and systemic effects…”
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Illuminating the functional and structural repertoire of human TBC/RABGAPs by Frasa, Marieke A. M., Koessmeier, Katja T., Ahmadian, M. Reza, Braga, Vania M. M.

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