Search Results - "Müller, Petr"

Catechol-O-methyl transferase suppresses cell invasion and interplays with MET signaling in estrogen dependent breast cancer by Janacova, Lucia, Stenckova, Michaela, Lapcik, Petr, Hrachovinova, Sarka, Bouchalova, Pavla, Potesil, David, Hrstka, Roman, Müller, Petr, Bouchal, Pavel

“…Catechol-O-methyl transferase (COMT) is involved in detoxification of catechol estrogens, playing cancer-protective role in cells producing or utilizing…”
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Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide by Lapcik, Petr, Sulc, Petr, Janacova, Lucia, Jilkova, Katerina, Potesil, David, Bouchalova, Pavla, Müller, Petr, Bouchal, Pavel

“…BackgroundDesmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node…”
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Docking-dependent Ubiquitination of the Interferon Regulatory Factor-1 Tumor Suppressor Protein by the Ubiquitin Ligase CHIP by Narayan, Vikram, Pion, Emmanuelle, Landré, Vivien, Müller, Petr, Ball, Kathryn L.

“…Characteristically for a regulatory protein, the IRF-1 tumor suppressor turns over rapidly with a half-life of between 20–40 min. This allows IRF-1 to reach…”
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A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize by Kosztyu, Pavlína, Slaninová, Iva, Valčíková, Barbora, Verlande, Amandine, Müller, Petr, Paleček, Jan J, Uldrijan, Stjepan

“…Mdm2 and MdmX are related proteins serving in the form of the Mdm2 homodimer or Mdm2/MdmX heterodimer as an E3 ubiquitin ligase for the tumor suppressor p53…”
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Pull-down Assay on Streptavidin Beads and Surface Plasmon Resonance Chips for SWATH-MS-based Interactomics by MARYÁŠ, JOSEF, FAKTOR, JAKUB, ČÁPKOVÁ, LENKA, MÜLLER, PETR, SKLÁDAL, PETR, BOUCHAL, PAVEL

“…Background/Aim: Pul-down assay is a popular in vitro method for identification of physical interactors of selected proteins. Here, for the first time, we…”
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The Role of HSP70 in Cancer and its Exploitation as a Therapeutic Target by Veronika, Martinková, Filip, Trčka, Bořivoj, Vojtěšek, Petr, Müller

“…Sustained proliferation and genetic instability of cancer cells are associated with enhanced production of mutated and conformationally unstable proteins…”
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The Role of HSF1 Protein in Malignant Transformation by Oliver, Šimončík, Michal, Pastorek, Bořivoj, Vojtěšek, Petr, Müller

“…The heat shock transcription factor, HSF1, is the main regulator of the proteotoxic stress response that orchestrates the adaptation of cells to stress…”
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Experimental investigation of the compressive strength of normal-strength air-entrained concrete at high temperatures by Holan, Jakub, Novák, Josef, Müller, Petr, Štefan, Radek

“…•Air entrainment seems to reduce the risk of concrete spalling.•Air entrainment decreases the compressive strength of concrete at high temperatures.•Air…”
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Direct activation of HSF1 by macromolecular crowding and misfolded proteins by Simoncik, Oliver, Tichy, Vlastimil, Durech, Michal, Hernychova, Lenka, Trcka, Filip, Uhrik, Lukas, Bardelcik, Miroslav, Coates, Philip J, Vojtesek, Borivoj, Muller, Petr

“…Stress responses play a vital role in cellular survival against environmental challenges, often exploited by cancer cells to proliferate, counteract genomic…”
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Assessment of structures repeatedly exposed to thermal loading and extinguishing water: a case study of a firefighting training facility by Petr Müller, Martin Benýšek, Radek Štefan, Jakub Holan, Šárka Košťálová

“…When designing a new structure or assessing an existing one, the risk of fire and its effect on the structure must be considered. Structures are usually…”
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Toxicity of external beam accelerated partial-breast irradiation (APBI) in adjuvant therapy of early-stage breast cancer: prospective randomized study by Burkon, Petr, Selingerova, Iveta, Slavik, Marek, Holanek, Milos, Vrzal, Miroslav, Coufal, Oldrich, Polachova, Katerina, Muller, Petr, Slampa, Pavel, Kazda, Tomas

“…Accelerated partial breast irradiation (APBI) is an alternative breast-conserving therapy approach where radiation is delivered in less time compared to whole…”
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AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway by Hrstka, Roman, Bouchalova, Pavla, Michalova, Eva, Matoulkova, Eva, Muller, Petr, Coates, Philip J., Vojtesek, Borivoj

“…The tumor suppressor p53 plays a key role in malignant transformation and tumor development. However, the frequency of p53 mutations within individual types of…”
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Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response by Mistrik, Martin, Skrott, Zdenek, Muller, Petr, Panacek, Ales, Hochvaldova, Lucie, Chroma, Katarina, Buchtova, Tereza, Vandova, Veronika, Kvitek, Libor, Bartek, Jiri

“…Despite proteotoxic stress and heat shock being implicated in diverse pathologies, currently no methodology to inflict defined, subcellular thermal damage…”
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IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation by Hároníková, Lucia, Coufal, Jan, Kejnovská, Iva, Jagelská, Eva B, Fojta, Miroslav, Dvořáková, Petra, Muller, Petr, Vojtesek, Borivoj, Brázda, Václav

“…Interferon-inducible protein 16 (IFI16) is a member of the HIN-200 protein family, containing two HIN domains and one PYRIN domain. IFI16 acts as a sensor of…”
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The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276 by Li, Ruidong, Zatloukalova, Pavlina, Muller, Petr, Gil-Mir, Maria, Kote, Sachin, Wilkinson, Simon, Kemp, Alain J, Hernychova, Lenka, Wang, Yaxin, Ball, Kathryn L, Tao, Kaixiong, Hupp, Ted, Vojtesek, Borivoj

“…The links between the p53/MDM2 pathway and the expression of pro-oncogenic immune inhibitory receptors in tumor cells are undefined. In this report, we…”
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Next-generation sequencing of a combinatorial peptide phage library screened against ubiquitin identifies peptide aptamers that can inhibit the in vitro ubiquitin transfer cascade by Lisowska, Małgorzata, Lickiss, Fiona, Gil-Mir, Maria, Huart, Anne-Sophie, Trybala, Zuzanna, Way, Luke, Hernychova, Lenka, Krejci, Adam, Muller, Petr, Krejcir, Radovan, Zhukow, Igor, Jurczak, Przemyslaw, Rodziewicz-Motowidło, Sylwia, Ball, Kathryn, Vojtesek, Borivoj, Hupp, Ted, Kalathiya, Umesh

“…Defining dynamic protein-protein interactions in the ubiquitin conjugation reaction is a challenging research area. Generating peptide aptamers that target…”
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A Cyclic Pentamethinium Salt Induces Cancer Cell Cytotoxicity through Mitochondrial Disintegration and Metabolic Collapse by Krejcir, Radovan, Krcova, Lucie, Zatloukalova, Pavlina, Briza, Tomas, Coates, Philip J, Sterba, Martin, Muller, Petr, Kralova, Jarmila, Martasek, Pavel, Kral, Vladimir, Vojtesek, Borivoj

“…Cancer cells preferentially utilize glycolysis for ATP production even in aerobic conditions (the Warburg effect) and adapt mitochondrial processes to their…”
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The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine by Jain, Saurabh, Aresu, Luca, Comazzi, Stefano, Shi, Jianguo, Worrall, Erin, Clayton, John, Humphries, William, Hemmington, Sandra, Davis, Paul, Murray, Euan, Limeneh, Asmare A, Ball, Kathryn, Ruckova, Eva, Muller, Petr, Vojtesek, Borek, Fahraeus, Robin, Argyle, David, Hupp, Ted R

“…Monoclonal antibodies are leading agents for therapeutic treatment of human diseases, but are limited in use by the paucity of clinically relevant models for…”
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Toskové a Gegové v Albánii a jejich pohled na Albánce v okolních státech by Petr Müller

“…This paper aims to examine ethnic identity of Albanians both inside and outside of Albania. This paper is based on field research and qualitative research…”
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The selection of a hydrophobic 7-phenylbutyl-7-deazaadenine-modified DNA aptamer with high binding affinity for the Heat Shock Protein 70 by Mulholland, Catherine, Jestřábová, Ivana, Sett, Arghya, Ondruš, Marek, Sýkorová, Veronika, Manzanares, C. Lorena, Šimončík, Oliver, Muller, Petr, Hocek, Michal

“…Nucleic acids aptamers often fail to efficiently target some proteins because of the hydrophilic character of the natural nucleotides. Here we present…”
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