Search Results - "Møllgård, Kjeld"

The meninges as barriers and facilitators for the movement of fluid, cells and pathogens related to the rodent and human CNS by Weller, Roy O., Sharp, Matthew M., Christodoulides, Myron, Carare, Roxana O., Møllgård, Kjeld

“…Meninges that surround the CNS consist of an outer fibrous sheet of dura mater (pachymeninx) that is also the inner periosteum of the skull. Underlying the…”
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RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis by Farooq, Muhammad, Lindbæk, Louise, Krogh, Nicolai, Doganli, Canan, Keller, Cecilie, Mönnich, Maren, Gonçalves, André Brás, Sakthivel, Srinivasan, Mang, Yuan, Fatima, Ambrin, Andersen, Vivi Søgaard, Hussain, Muhammad S., Eiberg, Hans, Hansen, Lars, Kjaer, Klaus Wilbrandt, Gopalakrishnan, Jay, Pedersen, Lotte Bang, Møllgård, Kjeld, Nielsen, Henrik, Baig, Shahid. M., Tommerup, Niels, Christensen, Søren Tvorup, Larsen, Lars Allan

“…Primary microcephaly (MCPH) is characterized by reduced brain size and intellectual disability. The exact pathophysiological mechanism underlying MCPH remains…”
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Markers for blood-brain barrier integrity: how appropriate is Evans blue in the twenty-first century and what are the alternatives? by Saunders, Norman R, Dziegielewska, Katarzyna M, Møllgård, Kjeld, Habgood, Mark D

“…In recent years there has been a resurgence of interest in brain barriers and various roles their intrinsic mechanisms may play in neurological disorders. Such…”
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PDGF-B Is Required for Development of the Glymphatic System by Munk, Anne Sofie, Wang, Wei, Bèchet, Nicholas Burdon, Eltanahy, Ahmed M., Cheng, Anne Xiaoan, Sigurdsson, Björn, Benraiss, Abdellatif, Mäe, Maarja A., Kress, Benjamin Travis, Kelley, Douglas H., Betsholtz, Christer, Møllgård, Kjeld, Meissner, Anja, Nedergaard, Maiken, Lundgaard, Iben

“…The glymphatic system is a highly polarized cerebrospinal fluid (CSF) transport system that facilitates the clearance of neurotoxic molecules through a…”
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The biological significance of brain barrier mechanisms: help or hindrance in drug delivery to the central nervous system? [version 1; peer review: 2 approved] by Saunders, Norman R, Habgood, Mark D, Møllgård, Kjeld, Dziegielewska, Katarzyna M

“…Barrier mechanisms in the brain are important for its normal functioning and development. Stability of the brain's internal environment, particularly with…”
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Structural characterization of SLYM-a 4th meningeal membrane by Plá, Virginia, Bitsika, Styliani, Giannetto, Michael J, Ladron-de-Guevara, Antonio, Gahn-Martinez, Daniel, Mori, Yuki, Nedergaard, Maiken, Møllgård, Kjeld

“…Traditionally, the meninges are described as 3 distinct layers, dura, arachnoid and pia. Yet, the classification of the connective meningeal membranes…”
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Mutations in C10orf11, a Melanocyte-Differentiation Gene, Cause Autosomal-Recessive Albinism by Grønskov, Karen, Dooley, Christopher M., Østergaard, Elsebet, Kelsh, Robert N., Hansen, Lars, Levesque, Mitchell P., Vilhelmsen, Kaj, Møllgård, Kjeld, Stemple, Derek L., Rosenberg, Thomas

“…Autosomal-recessive albinism is a hypopigmentation disorder with a broad phenotypic range. A substantial fraction of individuals with albinism remain…”
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Haploinsufficiency of TAB2 Causes Congenital Heart Defects in Humans by Thienpont, Bernard, Zhang, Litu, Postma, Alex V., Breckpot, Jeroen, Tranchevent, Léon-Charles, Van Loo, Peter, Møllgård, Kjeld, Tommerup, Niels, Bache, Iben, Tümer, Zeynep, van Engelen, Klaartje, Menten, Björn, Mortier, Geert, Waggoner, Darrel, Gewillig, Marc, Moreau, Yves, Devriendt, Koen, Larsen, Lars Allan

“…Congenital heart defects (CHDs) are the most common major developmental anomalies and the most frequent cause for perinatal mortality, but their etiology…”
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Response to Commentary on "Structural characterization of SLYM - a 4th meningeal membrane" by Julie Siegenthaler and Christer Betsholtz by Plá, Virginia, Bitsika, Styliani, Giannetto, Michael J, Ladrón-de-Guevara, Antonio, Gahn-Martinez, Daniel, Mori, Yuki, Nedergaard, Maiken, Møllgård, Kjeld

“…Histological studies have for decades documented that each of the classical meningeal membranes contains multiple fibroblast layers with distinct cellular…”
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Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide by Koehn, Liam M., Dziegielewska, Katarzyna M., Møllgård, Kjeld, Saudrais, Elodie, Strazielle, Nathalie, Ghersi-Egea, Jean-Francois, Saunders, Norman R., Habgood, Mark D.

“…Many pregnant women and prematurely born infants require medication for clinical conditions including cancer, cardiac defects and psychiatric disorders. In…”
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In response to "An "outer subarachnoid space": fact or artifact? A commentary on "Structural characterization of SLYM: a 4th meningeal membrane" fluids and barriers of the CNS (2023) 20:93 by V. Plá et al." by Plá, Virginia, Bitsika, Styliani, Giannetto, Michael J, Ladron-de-Guevara, Antonio, Gahn-Martinez, Daniel, Mori, Yuki, Nedergaard, Maiken, Møllgård, Kjeld

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Aquaporin 1 and the Na + /K + /2Cl - cotransporter 1 are present in the leptomeningeal vasculature of the adult rodent central nervous system by Li, Qianliang, Aalling, Nadia N, Förstera, Benjamin, Ertürk, Ali, Nedergaard, Maiken, Møllgård, Kjeld, Xavier, Anna L R

“…The classical view of cerebrospinal fluid (CSF) production posits the choroid plexus as its major source. Although previous studies indicate that part of CSF…”
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Outer brain barriers in rat and human development by Brøchner, Christian B, Holst, Camilla B, Møllgård, Kjeld

“…Complex barriers at the brain's surface, particularly in development, are poorly defined. In the adult, arachnoid blood-cerebrospinal fluid (CSF) barrier…”
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Molecular characterisation of transport mechanisms at the developing mouse blood-CSF interface: a transcriptome approach by Liddelow, Shane A, Temple, Sally, Møllgård, Kjeld, Gehwolf, Renate, Wagner, Andrea, Bauer, Hannelore, Bauer, Hans-Christian, Phoenix, Timothy N, Dziegielewska, Katarzyna M, Saunders, Norman R

“…Exchange mechanisms across the blood-cerebrospinal fluid (CSF) barrier in the choroid plexuses within the cerebral ventricles control access of molecules to…”
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Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach by Liddelow, Shane A, Dziegielewska, Katarzyna M, Ek, C Joakim, Habgood, Mark D, Bauer, Hannelore, Bauer, Hans-Christian, Lindsay, Helen, Wakefield, Matthew J, Strazielle, Nathalie, Kratzer, Ingrid, Møllgård, Kjeld, Ghersi-Egea, Jean-François, Saunders, Norman R

“…We provide comprehensive identification of embryonic (E15) and adult rat lateral ventricular choroid plexus transcriptome, with focus on junction-associated…”
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In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133 by Barraud, Perrine, Stott, Simon, Møllgård, Kjeld, Parmar, Malin, Björklund, Anders

“…The stage‐specific embryonic antigen 4 (SSEA4) is commonly used as a cell surface marker to identify the pluripotent human embryonic stem (ES) cells…”
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Subplate in the developing cortex of mouse and human by Wang, Wei Zhi, Hoerder‐Suabedissen, Anna, Oeschger, Franziska M., Bayatti, Nadhim, Ip, Bui Kar, Lindsay, Susan, Supramaniam, Veena, Srinivasan, Latha, Rutherford, Mary, Møllgård, Kjeld, Clowry, Gavin J., Molnár, Zoltán

“…The subplate is a largely transient zone containing precocious neurons involved in several key steps of cortical development. The majority of subplate neurons…”
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Cellular specificity of the blood-CSF barrier for albumin transfer across the choroid plexus epithelium by Liddelow, Shane A, Dzięgielewska, Katarzyna M, Møllgård, Kjeld, Whish, Sophie C, Noor, Natassya M, Wheaton, Benjamin J, Gehwolf, Renate, Wagner, Andrea, Traweger, Andreas, Bauer, Hannelore, Bauer, Hans-Christian, Saunders, Norman R

“…To maintain the precise internal milieu of the mammalian central nervous system, well-controlled transfer of molecules from periphery into brain is required…”
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Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study by Saunders, Norman R, Dziegielewska, Katarzyna M, Møllgård, Kjeld, Habgood, Mark D, Wakefield, Matthew J, Lindsay, Helen, Stratzielle, Nathalie, Ghersi-Egea, Jean-Francois, Liddelow, Shane A

“…The transcriptome of embryonic and adult rat lateral ventricular choroid plexus, using a combination of RNA-Sequencing and microarray data, was analyzed by…”
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Dissecting spatio-temporal protein networks driving human heart development and related disorders by Larsen, Lars A, Møllgård, Kjeld, Roque, Francisco S, Donahoe, Patricia K, Seidman, Jonathan G, Seidman, Christine E, Tommerup, Niels, Wiese, Cornelia, Lage, Kasper, Brunak, Søren, Roberts, Amy E, Smoot, Leslie B, Wakimoto, Hiroko, Gorham, Joshua M, Christoffels, Vincent M, Pu, William T, Greenway, Steven, Workman, Christopher T, Rigina, Olga, Hansen, Niclas T, Bendsen, Eske

“…Aberrant organ development is associated with a wide spectrum of disorders, from schizophrenia to congenital heart disease, but systems‐level insight into the…”
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