Search Results - "Møllersen, Linda"
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Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice
Published in PLoS genetics (01-12-2010)“…Huntington's disease (HD) is one of several neurodegenerative disorders caused by expansion of CAG repeats in a coding gene. Somatic CAG expansion rates in HD…”
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Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease
Published in Molecular brain (28-05-2016)“…Alzheimer's disease (AD) is a progressive, multifactorial neurodegenerative disorder that is the main cause of dementia globally. AD is associated with…”
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Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice
Published in Human molecular genetics (15-11-2012)“…Huntington's disease (HD) is a progressive neurodegenerative disorder caused by trinucleotide repeat (TNR) expansions. We show here that somatic TNR expansions…”
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Dietary retinoic acid supplementation stimulates intestinal tumour formation and growth in multiple intestinal neoplasia (Min)/+ mice
Published in Carcinogenesis (New York) (01-01-2004)“…Chemopreventive activity by retinoic acid (RA) has been demonstrated previously in rat colon. The spontaneous tumourigenesis in the Min/+ mouse, which harbours…”
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Effects of Anthocyanins on CAG Repeat Instability and Behaviour in Huntington's Disease R6/1 Mice
Published in PLoS currents (05-07-2016)“…Huntington's disease (HD) is a progressive neurodegenerative disorder caused by CAG repeat expansions in the HTT gene. Somatic repeat expansion in the R6/1…”
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Continuous and Periodic Expansion of CAG Repeats in Huntington's Disease R6/1 Mice: e1001242
Published in PLoS genetics (01-12-2010)“…Huntington's disease (HD) is one of several neurodegenerative disorders caused by expansion of CAG repeats in a coding gene. Somatic CAG expansion rates in HD…”
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Loss of Heterozygosity and Nonsense Mutation in Apc in Azoxymethane-induced Colonic Tumours in Min Mice
Published in Anticancer research (01-09-2004)“…C57BL/6J Min/+ mice, which carry a nonsense mutation in Apc, were injected twice neonatally with 5 mg azoxymethane (AOM) /kg body weight. AOM treatment in…”
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Adenomatous polyposis coli truncation mutations in 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP)-induced intestinal tumours of multiple intestinal neoplasia mice
Published in Mutation research. Genetic toxicology and environmental mutagenesis (10-01-2004)“…The heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) induces intestinal tumours in C57BL/6J-multiple intestinal neoplasia ( Min)/ +…”
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One dose of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5- f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Apc gene
Published in Mutation research (27-05-2002)“…The C57BL/6J- Min/+ (multiple intestinal neoplasia) mouse has a heterozygous nonsense Apc Min (adenomatous polyposis coli) mutation, and numerous adenomas…”
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Adenomatous polyposis coli truncation mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumours of multiple intestinal neoplasia mice
Published in Mutation research (10-01-2004)“…The heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induces intestinal tumours in C57BL/6J-multiple intestinal neoplasia (Min)/+…”
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