Search Results - "Møller, Bjarne K."

Immunomodulatory effects of clozapine and their clinical implications: What have we learned so far? by Røge, Rasmus, Møller, Bjarne K, Andersen, Christian R, Correll, Christoph U, Nielsen, Jimmi

“…Abstract Clozapine remains the drug of choice for treatment resistant schizophrenia, but is associated with potentially life threatening side effects,…”
Get full text

Measured Levels of Human Adipose Tissue–Derived Stem Cells in Adipose Tissue Is Strongly Dependent on Harvesting Method and Stem Cell Isolation Technique by Alstrup, Toke, Eijken, Marco, Brunbjerg, Mette Eline, Hammer-Hansen, Niels, Møller, Bjarne K., Damsgaard, Tine Engberg

“…Adipose tissue-derived stem cells are of great interest because of their properties of immune modulation, tissue regeneration, and multipotent differentiation…”
Get full text

Mesenchymal stromal cell treatment of donor kidneys during ex vivo normothermic machine perfusion: A porcine renal autotransplantation study by Lohmann, Stine, Pool, Merel B. F., Rozenberg, Kaithlyn M., Keller, Anna K., Moers, Cyril, Møldrup, Ulla, Møller, Bjarne K., Lignell, Stina J. M., Krag, Søren, Sierra‐Parraga, Jesus M., Lo Faro, Maria L., Hunter, James, Hoogduijn, Martin J., Baan, Carla C., Leuvenink, Henri G. D., Ploeg, Rutger J., Eijken, Marco, Jespersen, Bente

“…Normothermic machine perfusion (NMP) of injured kidneys offers the opportunity for interventions to metabolically active organs prior to transplantation…”
Get full text

Ex Vivo Administration of Mesenchymal Stromal Cells in Kidney Grafts Against Ischemia-reperfusion Injury—Effective Delivery Without Kidney Function Improvement Posttransplant by Lohmann, Stine, Eijken, Marco, Møldrup, Ulla, Møller, Bjarne K., Hunter, James, Moers, Cyril, Leuvenink, Henri, Ploeg, Rutger J., Clahsen-van Groningen, Marian C., Hoogduijn, Martin, Baan, Carla C., Keller, Anna Krarup, Jespersen, Bente

“…BACKGROUND:Mesenchymal stromal cell (MSC) therapy may improve renal function after ischemia-reperfusion injury in transplantation. Ex vivo renal intraarterial…”
Get full text

Monocyte phenotype and extracellular vesicles in HIV-1, HIV-2, and HIV-1/2 dual infection by Hønge, Bo L., Andersen, Morten N, Petersen, Mikkel S., Jespersen, Sanne, Medina, Candida, Té, David DS, Kjerulff, Bertram, Laursen, Alex L., Møller, Holger J., Wejse, Christian, Krarup, Henrik, Møller, Bjarne K., Erikstrup, Christian

“…AIDS-defining illness develops at higher CD4+ T-cell counts in individuals infected with HIV-2 compared with HIV-1 infected, which suggests that the two types…”
Get full text

Kinetics of Torque Teno virus in heart transplant patients by Berg, Randi, Clemmensen, Tor S., Petersen, Mikkel S., Mogensen, Lone J.H., Christiansen, Mette, Rolid, Katrine, Nytrøen, Kari, Møller, Bjarne K., Gullestad, Lars, Eiskjær, Hans, Koefoed-Nielsen, Pernille

“…End-stage heart failure often requires heart transplantation as a life-prolonging treatment. Immunosuppressive therapy is necessary to avoid rejection, but is…”
Get full text

Reparative effect of mesenchymal stromal cells on endothelial cells after hypoxic and inflammatory injury by Sierra-Parraga, Jesus M, Merino, Ana, Eijken, Marco, Leuvenink, Henri, Ploeg, Rutger, Maller, Bjarne K, Jespersen, Bente, Baan, Carla C, Hoogduijn, Martin J

“…Abstract Background The renal endothelium is a prime target for ischemia-reperfusion injury (IRI) during donation and transplantation procedures. Mesenchymal…”
Get full text

Effects of Normothermic Machine Perfusion Conditions on Mesenchymal Stromal Cells by Sierra Parraga, Jesus M, Rozenberg, Kaithlyn, Eijken, Marco, Leuvenink, Henri G, Hunter, James, Merino, Ana, Moers, Cyril, Møller, Bjarne K, Ploeg, Rutger J, Baan, Carla C, Jespersen, Bente, Hoogduijn, Martin J

“…normothermic machine perfusion (NMP) of transplant kidneys allows assessment of kidney quality and targeted intervention to initiate repair processes prior to…”
Get full text

Dynamics of circulating dendritic cells and cytokines after kidney transplantation—No effect of remote ischaemic conditioning by Nielsen, Marie B., Ravlo, Kristian, Eijken, Marco, Krogstrup, Nicoline V., Bue Svendsen, Morten, Abdel‐Halim, Chadi, Steen Petersen, Mikkel, Birn, Henrik, Oltean, Mihai, Jespersen, Bente, Møller, Bjarne K.

“…Inflammation resulting from ischaemia/reperfusion injury can cause kidney graft dysfunction, increase the risk of delayed graft function and possibly reduce…”
Get full text

Impact of preadmission anti‐inflammatory drug use on the risk of RBC transfusion in elderly hip fracture patients: a Danish nationwide cohort study, 2005–2016 by Glassou, Eva N., Kristensen, Nickolaj, Møller, Bjarne K., Erikstrup, Christian, Hansen, Torben B., Pedersen, Alma B.

“…BACKGROUND Do prescription drugs with anti‐inflammatory properties such as nonsteroidal anti‐inflammatory drugs (NSAIDs), corticosteroids, and statins increase…”
Get full text

HLA‐DQB106:276, a novel HLA allele fund in a patient from Guinea‐Bissau by Hønge, Bo L., Christiansen, Mette, Medina, Candida, Møller, Bjarne K., Erikstrup, Christian

“…DQB1*06:276 differs from DQB1*06:03:01:01 by amino acid substitutions p.T71A, p.G74S, and p.L75V in exon 2…”
Get full text

Non-random pairing of CD46 isoforms with skewing towards BC2 and C2 in activated and memory/effector T cells by Hansen, Aida S., Bundgaard, Bettina B., Møller, Bjarne K., Höllsberg, Per

“…CD46 is a glycoprotein with important functions in innate and adaptive immune responses. Functionally different isoforms are generated by alternative splicing…”
Get full text

Early Immunological Effects of Ischemia-Reperfusion Injury: No Modulation by Ischemic Preconditioning in a Randomised Crossover Trial in Healthy Humans by Lange, Thomas H, Eijken, Marco, Baan, Carla, Petersen, Mikkel Steen, Bibby, Bo Martin, Jespersen, Bente, Møller, Bjarne K

“…Ischemic preconditioning (IPC) has been protective against ischemia-reperfusion injury (IRI), but the underlying mechanism is poorly understood. We examined…”
Get full text

Plasma collection and supply in Europe: Proceedings of an International Plasma and Fractionation Association and European Blood Alliance symposium by Domanović, Dragoslav, Bonsdorff, Leni, Tiberghien, Pierre, Strengers, Paul, Hotchko, Matthew, O'Leary, Peter, Thibert, Jean‐Baptiste, Magnussen, Karin, Erikstrup, Christian, Spekman, Marloes, Chesneau, Stuart, Jones, Judy, Møller, Bjarne K., Verheggen, Peter, Gogarty, Gerard, Elzaabi, Mazen, Angelis, Vincenzo, Candura, Fabio, Mali, Polonca, Rossi, Françoise, Rodrigues, Bernardo, Sepetiene, Ramune, Lenzen, Thomas, Walsemann, Stephan, Perry, Robert, Plançon, Jean‐Philippe, So‐Osman, Cynthia, Durand‐Zaleski, Isabelle, Facco, Giuseppina, Thijssen‐Timmer, Daphne

“…At the symposium organized by the International Plasma and Fractionation Association and European Blood Alliance, experts presented their views and experiences…”
Get full text

Two novel HLA‐B alleles, HLA‐B53:01:17 and ‐B58:83, found in patients from Guinea‐Bissau by Christiansen, Mette, Erikstrup, Christian, Medina, Candida, Møller, Bjarne K., Hønge, Bo L.

“…Novel HLA‐B alleles HLA‐B*53:01:17 and HLA‐B*58:83 are described in two patients from Guinea‐Bissau…”
Get full text

T-cell and B-cell perturbations identify distinct differences in HIV-2 compared with HIV-1-induced immunodeficiency by Hønge, Bo L, Petersen, Mikkel S, Jespersen, Sanne, Medina, Candida, Té, David D.S, Kjerulff, Bertram, Engell-Sørensen, Thomas, Madsen, Tina, Laursen, Alex L, Wejse, Christian, Krarup, Henrik, Møller, Bjarne K, Erikstrup, Christian

“…BACKGROUND:For unknown reasons, HIV-2 is less pathogenic than HIV-1, and HIV-2-induced immunodeficiency may be different from that caused by HIV-1. Previous…”
Get full text

CD46 activation induces distinct CXCL-10 response in monocytes and monocyte-derived dendritic cells by Hansen, Aida S., Biltoft, Mette, Bundgaard, Bettina, Bohn, Anja B., Møller, Bjarne K., Höllsberg, Per

“…•CD46 activation reduces CXCL-10 production from moDCs but not from monocytes.•CD46 activation does not alter surface markers of moDC maturation.•Monocyte…”
Get full text

T-cell and B-cell perturbations are similar in ART-naive HIV-1 and HIV-1/2 dually infected patients by Hønge, Bo L, Petersen, Mikkel S, Jespersen, Sanne, Medina, Candida, Té, David D.S, Kjerulff, Bertram, Jensen, Mads M, Steiniche, Ditte, Esbjörnsson, Joakim, Laursen, Alex L, Wejse, Christian, Krarup, Henrik, Møller, Bjarne K, Erikstrup, Christian

“…BACKGROUND:HIV-2 may slow progression of a subsequently acquired HIV-1 infection through cross-neutralizing antibodies and polyfunctional CD8 T cells. We…”
Get full text

CD46 is a potent co-stimulatory receptor for expansion of human IFN-γ-producing CD8+ T cells by Hansen, Aida S., Slater, Josefine, Biltoft, Mette, Bundgaard, Bettina B., Møller, Bjarne K., Höllsberg, Per

“…•Activation of CD46 induces rapid down-modulation of CD46 expression on the surface of CD8+ T cells.•CD46 co-stimulation potently induces CD8+ T cell…”
Get full text

Metformin modulates immune cell infiltration into the kidney during unilateral ureteral obstruction in mice by Christensen, Michael, Nørgård, Mikkel Ø., Jensen, Michael S., Møller, Bjarne K., Nørregaard, Rikke

“…Metformin is today the first choice treatment for type‐2 diabetes, but has also protective effects in several renal disease models. Previously, we have…”
Get full text