Search Results - "Möhler, Christian"

Evaluation of Stopping-Power Prediction by Dual- and Single-Energy Computed Tomography in an Anthropomorphic Ground-Truth Phantom by Wohlfahrt, Patrick, Möhler, Christian, Richter, Christian, Greilich, Steffen

“…To determine the accuracy of particle range prediction for proton and heavier ion radiation therapy based on dual-energy computed tomography (DECT) in a…”
Get full text

Clinical implementation of dual-energy CT for proton treatment planning on pseudo-monoenergetic CT scans by Wohlfahrt, Patrick, MSc, Möhler, Christian, MSc, Hietschold, Volker, PhD, Menkel, Stefan, PhD, Greilich, Steffen, PhD, Krause, Mechthild, MD PhD, Baumann, Michael, MD PhD, Enghardt, Wolfgang, PhD, Richter, Christian, PhD

“…Abstract Purpose To determine whether a standardized clinical application of dual-energy CT (DECT) for proton treatment planning based on pseudo-monoenergetic…”
Get full text

Dual-energy CT based proton range prediction in head and pelvic tumor patients by Wohlfahrt, Patrick, Möhler, Christian, Stützer, Kristin, Greilich, Steffen, Richter, Christian

“…To reduce range uncertainty in particle therapy, an accurate computation of stopping-power ratios (SPRs) based on computed tomography (CT) is crucial. Here, we…”
Get full text

Range prediction for tissue mixtures based on dual-energy CT by Möhler, Christian, Wohlfahrt, Patrick, Richter, Christian, Greilich, Steffen

“…The use of dual-energy CT (DECT) potentially decreases range uncertainties in proton and ion therapy treatment planning via determination of the involved…”
Get more information

Experimental verification of stopping-power prediction from single- and dual-energy computed tomography in biological tissues by Möhler, Christian, Russ, Tom, Wohlfahrt, Patrick, Elter, Alina, Runz, Armin, Richter, Christian, Greilich, Steffen

“…An experimental setup for consecutive measurement of ion and x-ray absorption in tissue or other materials is introduced. With this setup using a 3D-printed…”
Get more information

Technical Note: Radiological properties of tissue surrogates used in a multimodality deformable pelvic phantom for MR-guided radiotherapy by Niebuhr, Nina I., Johnen, Wibke, Güldaglar, Timur, Runz, Armin, Echner, Gernot, Mann, Philipp, Möhler, Christian, Pfaffenberger, Asja, Jäkel, Oliver, Greilich, Steffen

“…Purpose: Phantom surrogates were developed to allow multimodal [computed tomography (CT), magnetic resonance imaging (MRI), and teletherapy] and…”
Get full text

A deep image-to-image network organ segmentation algorithm for radiation treatment planning: principles and evaluation by Marschner, Sebastian, Datar, Manasi, Gaasch, Aurélie, Xu, Zhoubing, Grbic, Sasa, Chabin, Guillaume, Geiger, Bernhard, Rosenman, Julian, Corradini, Stefanie, Niyazi, Maximilian, Heimann, Tobias, Möhler, Christian, Vega, Fernando, Belka, Claus, Thieke, Christian

“…Abstract Background We describe and evaluate a deep network algorithm which automatically contours organs at risk in the thorax and pelvis on computed…”
Get full text

Correction: A deep image-to-image network organ segmentation algorithm for radiation treatment planning: principles and evaluation by Marschner, Sebastian, Datar, Manasi, Gaasch, Aurélie, Xu, Zhoubing, Grbic, Sasa, Chabin, Guillaume, Geiger, Bernhard, Rosenman, Julian, Corradini, Stefanie, Niyazi, Maximilian, Heimann, Tobias, Möhler, Christian, Vega, Fernando, Belka, Claus, Thieke, Christian

Get full text

On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy by Möhler, Christian, Wohlfahrt, Patrick, Richter, Christian, Greilich, Steffen

“…Dual-energy computed tomography enables the determination of relative electron density and effective atomic number. As this can increase accuracy in…”
Get full text

Methodological accuracy of image‐based electron density assessment using dual‐energy computed tomography by Möhler, Christian, Wohlfahrt, Patrick, Richter, Christian, Greilich, Steffen

“…Purpose Electron density is the most important tissue property influencing photon and ion dose distributions in radiotherapy patients. Dual‐energy computed…”
Get full text

Reduction of clinical safety margins in proton therapy enabled by the clinical implementation of dual-energy CT for direct stopping-power prediction by Peters, Nils, Wohlfahrt, Patrick, Hofmann, Christian, Möhler, Christian, Menkel, Stefan, Tschiche, Maria, Krause, Mechthild, Troost, Esther G.C., Enghardt, Wolfgang, Richter, Christian

“…•With DirectSPR, range uncertainties can be reduced below 2% of the particle range.•DirectSPR was for the first time introduced into routine clinical…”
Get full text

Comment on: Dosimetric comparison of stopping‐power calibration with dual‐energy CT and single‐energy CT in proton therapy treatment planning [Med. Phys. 43(6), 2845‐2854 (2016)] by Wohlfahrt, Patrick, Möhler, Christian, Greilich, Steffen, Richter, Christian

Get full text

Reply to “Comment on Methodological accuracy of image‐based electron density assessment using dual‐energy computed tomography” [Med. Phys. 44, 2429–2437 (2017)] by Möhler, Christian, Wohlfahrt, Patrick, Richter, Christian, Greilich, Steffen

Get full text

Dual-Energy Computed Tomography to Assess Intra- and Inter-Patient Tissue Variability for Proton Treatment Planning of Patients With Brain Tumor by Wohlfahrt, Patrick, Möhler, Christian, Troost, Esther G.C., Greilich, Steffen, Richter, Christian

“…Range prediction in particle therapy is associated with an uncertainty originating from calculating the stopping-power ratio (SPR) based on x-ray computed…”
Get full text

Reply to “Comment on Methodological accuracy of image‐based electron density assessment using dual‐energy computed tomography” [Med. Phys. 44, 2429‐2437 (2017)] by Möhler, Christian, Wohlfahrt, Patrick, Richter, Christian, Greilich, Steffen

Get full text

Refinement of the Hounsfield look‐up table by retrospective application of patient‐specific direct proton stopping‐power prediction from dual‐energy CT by Wohlfahrt, Patrick, Möhler, Christian, Enghardt, Wolfgang, Krause, Mechthild, Kunath, Daniela, Menkel, Stefan, Troost, Esther G. C., Greilich, Steffen, Richter, Christian

“…Background and Purpose Proton treatment planning relies on an accurate determination of stopping‐power ratio (SPR) from x‐ray computed tomography (CT). A…”
Get full text

Novel dosimetric validation of a commercial CT scanner based deep learning automated contour solution for prostate radiotherapy by Berenato, Salvatore, Williams, Matthew, Woodley, Owain, Möhler, Christian, Evans, Elin, Millin, Anthony E., Wheeler, Philip A.

“…•OAR delineation is a critical component in modern radiotherapy pathways.•A novel dosimetric methodology was used to evaluate AI contours for prostate OARs.•3…”
Get full text

A clinical and time savings evaluation of a deep learning automatic contouring algorithm by Ginn, John S., Gay, Hiram A., Hilliard, Jessica, Shah, Jainil, Mistry, Nilesh, Möhler, Christian, Hugo, Geoffrey D., Hao, Yao

“…Automatic contouring algorithms may streamline clinical workflows by reducing normal organ-at-risk (OAR) contouring time. Here we report the first…”
Get full text

[I206] Dual energy CT for improved range prediction in proton therapy: What can we gain? by Richter, Christian, Wohlfahrt, Patrick, Möhler, Christian, Greilich, Steffen

“…For about a decade, dual-energy CT (DECT) has been clinically available, mainly for radiology applications. In contrast, in the field of radiotherapy DECT has…”
Get full text

Clinical Validation of Siemens’ Syngo.via Automatic Contouring System by Pera, Óscar, Martínez, Álvaro, Möhler, Christian, Hamans, Bob, Vega, Fernando, Barral, Fernando, Becerra, Nuria, Jimenez, Rafael, Fernandez-Velilla, Enric, Quera, Jaume, Algara, Manuel

“…The manual delineation of organs at risk is a process that requires a great deal of time both for the technician and for the physician. Availability of…”
Get full text