Search Results - "Möbest, D."

Serum-free ex vivo expansion of CD34+ hematopoietic progenitor cells by Möbest, Dieter, Mertelsmann, Roland, Henschler, Reinhard

“…In an effort to obtain defined culture conditions for ex vivo expansion of hematopoietic stem and progenitor cells which avoid the supplementation of serum, we…”
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Evaluation of processed bovine cancellous bone matrix seeded with syngenic osteoblasts in a critical size calvarial defect rat model by Kneser, U., Stangenberg, L., Ohnolz, J., Buettner, O., Stern‐Straeter, J., Möbest, D., Horch, R. E., Stark, G. B., Schaefer, D. J.

“…Introduction: Biologic bone substitutes may offer alternatives to bone grafting procedures. The aim of this study was to evaluate a preformed bone substitute…”
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Adhesion and Migration Are Differentially Regulated in Hematopoietic Progenitor Cells by Cytokines and Extracellular Matrix by Strobel, Eva-Susanne, Möbest, Dieter, von Kleist, Sabine, Dangel, Matthias, Ries, Stefan, Mertelsmann, Roland, Henschler, Reinhard

“…The conditions that control the migratory status of hematopoietic progenitor cells on extracellular matrix (ECM) and that decide whether a cell migrates or…”
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Novel integrin-dependent platelet malfunction in siblings with leukocyte adhesion deficiency-III (LAD-III) caused by a point mutation in FERMT3 by Jurk, Kerstin, Schulz, Ansgar S, Kehrel, Beate E, Räpple, Daniel, Schulze, Harald, Möbest, Dieter, Friedrich, Wilhelm W, Omran, Heymut, Deak, Erika, Henschler, Reinhard, Scheele, Jürgen S, Zieger, Barbara

“…Leukocyte adhesion deficiency-III (LAD-III) also called leukocyte adhesion deficiency-1/variant (LAD1v) is a rare congenital disease caused by defective…”
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Differential Kinetics of Primitive Hematopoietic Cells Assayed In Vitro and In Vivo During Serum‐Free Suspension Culture of CD34+ Blood Progenitor Cells by Möbest, Dieter, Goan, Silvia‐Renate, Junghahn, Ilse, Winkler, Julia, Fichtner, Iduna, Becker, Michael, de Lima‐Hahn, Elisete, Mertelsmann, Roland, Henschler, Reinhard

“…So far, blood progenitor cells (BPC) expanded ex vivo in the absence of stromal cells have not been demonstrated to reconstitute hematopoiesis in myeloablated…”
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Transforming growth factor‐beta 1 delays formation of granulocyte‐macrophage colony‐forming cells, but spares more primitive progenitors during ex vivo expansion of CD34+ haemopoietic progenitor cells by Garbe, Annette, Spyridonidis, Alexandros, Möbest, Dieter, Schmoor, Claudia, Mertelsmann, Roland, Henschler, Reinhard

“…Ex vivo culture and expansion of autologous haemopoietic transplants has been developed to improve tumour cell purging and accelerate haemopoietic…”
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Efficient serum-free retroviral gene transfer into primitive human hematopoietic progenitor cells by a defined, high-titer, nonconcentrated vector-containing medium by Glimm, H, Flügge, K, Möbest, D, Hofmann, V M, Postmus, J, Henschler, R, Lange, W, Finke, J, Kiem, H P, Schulz, G, Rosenthal, F, Mertelsmann, R, von Kalle, C

“…Defined serum-free conditions have great conceptual advantages for the biological safety and standardization of clinical gene transfer into hematopoietic stem…”
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SDF-1α-induced intracellular calcium transient involves Rho GTPase signalling and is required for migration of hematopoietic progenitor cells by Henschler, Reinhard, Piiper, Albrecht, Bistrian, Roxana, Möbest, Dietrich

“…Signalling through the chemokine stromal derived factor (SDF)-1α and its receptor CXCR4 has been recognized as a key event in the migratory response of…”
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Role of the monomeric GTPase Rho in hematopoietic progenitor cell migration and transplantation by Göttig, Stephan, Möbest, Dietrich, Rüster, Brigitte, Grace, Bithiah, Winter, Sylvia, Seifried, Erhard, Gille, Jens, Wieland, Thomas, Henschler, Reinhard

“…To investigate the role of the monomeric guanosine triphosphatase (GTPase) Rho on migration of hematopoietic progenitor cells (HPC), we employed different…”
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Differentiation of osteoblasts in three-dimensional culture in processed cancellous bone matrix: quantitative analysis of gene expression based on real-time reverse transcription-polymerase chain reaction by Stangenberg, Lars, Schaefer, Dirk J, Buettner, Olaf, Ohnolz, Jan, Möbest, Dieter, Horch, Raymund E, Stark, G Björn, Kneser, Ulrich

“…Processed bovine cancellous bone (PBCB) is an attractive material for tissue engineering of bone. It is biocompatible, osteoconductive, nonimmunogenic, and…”
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