Search Results - "Mózes, Emese"
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Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit
Published in Journal of Alzheimer's disease (01-01-2013)“…Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β peptides (Aβ) as perivascular deposits and senile plaques in the brain. The intake…”
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Journal Article -
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Proteome-wide study of endoplasmic reticulum stress induced by thapsigargin in N2a neuroblastoma cells
Published in Neurochemistry international (01-01-2013)“…► Strong crosstalk between mitochondria and endoplasmic reticulum. ► Upregulated mitochondrial enzymes during endoplasmic reticulum stress. ► Potentially…”
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Journal Article -
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Alzheimer risk factors age and female sex induce cortical Aβ aggregation by raising extracellular zinc
Published in Molecular psychiatry (01-11-2020)“…Aging and female sex are the major risk factors for Alzheimer’s disease and its associated brain amyloid-β (Aβ) neuropathology, but the mechanisms mediating…”
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Journal Article -
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A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays
Published in Brain research bulletin (10-04-2012)“…Highlights ► Using brain tissue slices for measuring Aβ toxicity with MTT and LDH assay. ► Separate and simultaneous effect of OGD and Aβ on hippocampal slice…”
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Journal Article -
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Innovative Approach for the Application of MTT, LDH and Bis-ANS: Ex Vivo Modelling of the Extracellular Beta-Amyloid Precipitation
Published 01-01-2021“…1.1. Hippocampal slices for modelling events in Alzheimer’s diseaseAlzheimer’s disease (AD) results in progressive loss of tissue throughout the brain, in…”
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Dissertation -
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A novel application of the fluorescent dye bis-ANS for labeling neurons in acute brain slices
Published in Brain research bulletin (10-10-2011)“…Highlights ► Cell-impermeant oligomer specific fluorescent dye, bis-ANS. ► Labeling mechanically damaged but still viable neurons in acute brain slices. ► Both…”
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Journal Article -
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Alzheimer risk factors age and female sex induce cortical A[beta] aggregation by raising extracellular zinc
Published in Molecular psychiatry (01-11-2020)“…Aging and female sex are the major risk factors for Alzheimer's disease and its associated brain amyloid-[beta] (A[beta]) neuropathology, but the mechanisms…”
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Journal Article