Search Results - "Míquel, Joaquín"

Adaptive immune response during hepatitis C virus infection by Larrubia, Juan Ramón

“…Hepatitis C virus(HCV)infection affects about 170 million people worldwide and it is a major cause of liver cirrhosis and hepatocellular carcinoma.HCV is a…”
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HBsAg level defines different clinical phenotypes of HBeAg(-) chronic HBV infection related to HBV polymerase-specific CD8 + cell response quality by Peña-Asensio, Julia, Calvo-Sánchez, Henar, Miquel-Plaza, Joaquín, Sanz-de-Villalobos, Eduardo, González-Praetorius, Alejandro, Delgado-Fernandez, Alberto, Torralba, Miguel, Larrubia, Juan-Ramón

“…HBe-antigen(Ag)-negative chronic hepatitis B virus (HBV) infection is characterized by little liver fibrosis progression and vigorous HBV-multispecific CD8…”
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Hepatitis C virus-specific cytotoxic T cell response restoration after treatment-induced hepatitis C virus control by Larrubia, Juan-Ramón, Moreno-Cubero, Elia, Miquel, Joaquín, Sanz-de-Villalobos, Eduardo

“…Hepatitis C virus(HCV)-specific cytotoxic T cell(CTL) response plays a major role in viral control during spontaneous infection resolution. These cells develop…”
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IL-15 boosts activated HBV core-specific CD8+ progenitor cells via metabolic rebalancing in persistent HBV infection by Peña-Asensio, Julia, Calvo-Sánchez, Henar, Miquel, Joaquín, Sanz-de-Villalobos, Eduardo, González-Praetorius, Alejandro, Torralba, Miguel, Larrubia, Juan-Ramón

“…A rebalance between energy supply and demand in HBV-specific-CD8+ activated progenitor (AP) cells could restore the functionality of proliferative progeny (PP)…”
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Gamma-Chain Receptor Cytokines & PD-1 Manipulation to Restore HCV-Specific CD8 + T Cell Response during Chronic Hepatitis C by Peña-Asensio, Julia, Calvo, Henar, Torralba, Miguel, Miquel, Joaquín, Sanz-de-Villalobos, Eduardo, Larrubia, Juan-Ramón

“…Hepatitis C virus (HCV)-specific CD8 T cell response is essential in natural HCV infection control, but it becomes exhausted during persistent infection…”
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SAT-374-YI IL-15 plus anti-PDL-1 restores CD8 T-cell response against core but not against polymerase in chronic hepatitis B with extreme exhaustion-associated factors by Sánchez, Henar Calvo, Asensio, Julia Peña, Míquel, Joaquín, Villalobos, Eduardo Sanz-de, Delgado, Alberto, Torralba, Miguel, Praetorius, Alejandro González, Larrubia, Juan Ramon

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FRI-381 Detection of functional HBV-specific CD8+ response is associated with significant decrease of HBsAg level after treatment withdrawal in eAg (-)chronic hepatitis B by Sánchez, Henar Calvo, Asensio, Julia Peña, Míquel, Joaquín, Villalobos, Eduardo Sanz-de, Delgado, Alberto, Torralba, Miguel, Praetorius, Alejandro González, Larrubia, Juan Ramon

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Bacteremia with Raoultella planticola in the setting of acute pancreatitis complicated with acute cholangitis by Merino Rodríguez, Esther, Rebolledo Olmedo, Susana, Miquel Plaza, Joaquín

“…The bacterium Raoultella planticola (R planticola) is a rare pathogen in humans. We report a case of mild acute pancreatitis (MAP) of biliary origin with…”
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Interleukin-15 restores the reactivity of the peripheral memory-like pool in the exhausted hepatitis B virus-specific CD8+ T cell population during persistent HBeAg(-) infection by Asensio, Julia Peña, Villalobos, Eduardo Sanz-de, Míquel, Joaquín, Praetorius, Alejandro González, Larrubia, Juan Ramón

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FRI356 - Interleukin-15 restores the reactivity of the peripheral memory-like pool in the exhausted hepatitis B virus-specific CD8+ T cell population during persistent HBeAg(-) infection by Asensio, Julia Peña, Villalobos, Eduardo Sanz-de, Míquel, Joaquín, Praetorius, Alejandro González, Larrubia, Juan Ramón

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Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C by Juan Ramón Larrubia Selma Benito-Martínez Joaquín Miquel Miryam Calvino Eduardo Sanz-de-Villalobos Trinidad Parra-Cid

“…Hepatitis C virus（HCV）-specific CD8^＋ T cells play an important role in the resolution of HCV infection. Nevertheless, during chronic hepatitis C these cells…”
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FRI-146-Long-term nucleos (t)ide-analogue treatment in chronic hepatitis B eAg (–) together with a low level of HBsAg leads to a nonexhausted HBV-specific T CD8+ response by Asensio, Julia Peña, Villalobos, Eduardo Sanz de, Míquel, Joaquín, Madejón, Antonio, Martin, Antonio Olveira, Praetorius, Alejandro González, Guerra, Andrea Martínez de la, Rey, Francisco Javier Garcia-Samaniego, Larrubia, Juan Ramón

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Anti-PD-1/PD-L1 Based Combination Immunotherapy to Boost Antigen-Specific CD8 + T Cell Response in Hepatocellular Carcinoma by Peña-Asensio, Julia, Calvo, Henar, Torralba, Miguel, Miquel, Joaquín, Sanz-de-Villalobos, Eduardo, Larrubia, Juan-Ramón

“…Thirty to fifty percent of hepatocellular carcinomas (HCC) display an immune class genetic signature. In this type of tumor, HCC-specific CD8 T cells carry out…”
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Model to predict on‐treatment restoration of functional HBV‐specific CD8+ cell response foresees off‐treatment HBV control in eAg‐negative chronic hepatitis B by Peña‐Asensio, Julia, Calvo, Henar, Miquel, Joaquín, Sanz‐de‐Villalobos, Eduardo, González‐Praetorius, Alejandro, Torralba, Miguel, Larrubia, Juan‐Ramón

“…Summary Background Hepatitis B virus (HBV)‐specific CD8+ cell response restoration during nucleos(t)ide analogue (NUC) treatment could lead to off‐treatment…”
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Letter: the probability to predict HBV‐specific CD8+ cell response derived from HLA‐A2+ may not foresee the functional cure well in Asian off‐therapy cohort—authors' reply by Peña‐Asensio, Julia, Calvo, Henar, Miquel, Joaquín, Sanz‐de‐Villalobos, Eduardo, González‐Praetorius, Alejandro, Torralba, Miguel, Larrubia, Juan‐Ramón

“…LINKED CONTENT This article is linked to Pena‐Asensio et al papers. To view these articles, visit https://doi.org/10.1111/apt.16850 and…”
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Tumor necrosis family receptor superfamily member 9/tumor necrosis factor receptor-associated factor 1 pathway on hepatitis C viral persistence and natural history by Peña-Asensio, Julia, Sanz-de-Villalobos, Eduardo, Miquel, Joaquín, Larrubia, Juan Ramón

“…Hepatitis C virus (HCV) infection is an excellent immunological model for understanding the mechanisms developed by non-cytopathic viruses and tumors to evade…”
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Is it possible to stop nucleos(t)ide analogue treatment in chronic hepatitis B patients? by Moreno-Cubero, Elia, Del Arco, Robert T Sánchez, Peña-Asensio, Julia, de Villalobos, Eduardo Sanz, Míquel, Joaquín, Larrubia, Juan Ramón

“…Chronic hepatitis B (CHB) remains a challenging global health problem, with nearly one million related deaths per year. Nucleos(t)ide analogue (NA) treatment…”
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Bacteremia with Raoultella planticola in the setting of acute pancreatitis complicated with acute cholangitis by Miquel-Plaza, Joaquin, Merino-Rodriguez, Esther, Rebolledo-Olmedo, Susana

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Hepatitis B virus kinetics after nucleos(t)ide-analogue withdrawal in chronic HBeAg(-) hepatitis correlates with HBV-specific CD8+ response and HBsAg level by Asensio, Julia Peña, Villalobos, Eduardo Sanz-de, Míquel, Joaquiń, Praetorius, Alejandro González, Larrubia, Juan Ramón

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FRI355 - Hepatitis B virus kinetics after nucleos(t)ide-analogue withdrawal in chronic HBeAg(-) hepatitis correlates with HBV-specific CD8+ response and HBsAg level by Asensio, Julia Peña, Villalobos, Eduardo Sanz-de, Míquel, Joaquiń, Praetorius, Alejandro González, Larrubia, Juan Ramón

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