Search Results - "Mínguez, Sandra Santos"

Co-occurrence of cohesin complex and Ras signaling mutations during progression from myelodysplastic syndromes to secondary acute myeloid leukemia by Martín-Izquierdo, Marta, Abáigar, María, Hernández-Sánchez, Jesús M, Tamborero, David, López-Cadenas, Félix, Ramos, Fernando, Lumbreras, Eva, Madinaveitia-Ochoa, Andrés, Megido, Marta, Labrador, Jorge, Sánchez-Real, Javier, Olivier, Carmen, Dávila, Julio, Aguilar, Carlos, Rodríguez, Juan N, Martín-Nuñez, Guillermo, Santos-Mínguez, Sandra, Miguel-García, Cristina, Benito, Rocío, Díez-Campelo, María, Hernández-Rivas, Jesús M

“…Myelodysplastic syndromes (MDS) are hematological disorders at high risk of progression to secondary acute myeloid leukemia (sAML). However, the mutational…”
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Lifestyles, arterial aging, and its relationship with the intestinal and oral microbiota (MIVAS III study): a research protocol for a cross-sectional multicenter study by Lugones-Sánchez, Cristina, Santos-Mínguez, Sandra, Salvado, Rita, González-Sánchez, Susana, Tamayo-Morales, Olaya, Hoya-González, Amaya, Ramírez-Manent, José I, Magallón-Botaya, Rosa, Quesada-Rico, José A, Garcia-Cubillas, Miriam D, Rodríguez-Sánchez, Emiliano, Gómez-Marcos, Manuel A, Benito-Sanchez, Rocío, Mira, Alex, Hernandez-Rivas, Jesus M, Garcia-Ortiz, Luis

“…The microbiota is increasingly recognized as a significant factor in the pathophysiology of many diseases, including cardiometabolic diseases, with lifestyles…”
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Novel variants in GALE cause syndromic macrothrombocytopenia by disrupting glycosylation and thrombopoiesis by Marín-Quílez, Ana, Di Buduo, Christian Andrea, Díaz-Ajenjo, Lorena, Abbonante, Vittorio, Vuelta, Elena, Soprano, Paolo Maria, Miguel-García, Cristina, Santos-Mínguez, Sandra, Serramito-Gómez, Inmaculada, Ruiz-Sala, Pedro, Peñarrubia, María Jesús, Pardal, Emilia, Hernández-Rivas, Jesús María, González-Porras, José Ramón, García-Tuñón, Ignacio, Benito, Rocío, Rivera, José, Balduini, Alessandra, Bastida, José María

“…•GALE is expressed during late-stage megakaryopoiesis, regulating the glycosylation and surface exposure of GPIbα and β1 integrin.•Novel GALE variants cause…”
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Gut microbiota and its relationship with early vascular ageing in a Spanish population (MIVAS study) by Salvado, Rita, Santos‐Minguez, Sandra, Lugones‐Sánchez, Cristina, Gonzalez‐Sánchez, Susana, Tamayo‐Morales, Olaya, Quesada‐Rico, José A., Benito, Rocío, Rodríguez‐Sánchez, Emiliano, Gómez‐Marcos, Manuel A., Casado‐Vicente, Verónica, Guimarães‐Cunha, Pedro, Hernandez‐Rivas, Jesús M., Mira, Alex, García‐Ortiz, Luis, Hernández‐Sánchez, Jesús Mª, Maderuelo‐Fernández, José A, Agudo‐Conde, Cristina, Cabo‐Laso, Ángela, Sánchez‐Salgado, Benigna, Martín‐González, Mª Pilar, Garcia, Ana Garcia‐Puente, Hoya‐González, Amaya, Magallón‐Botaya, Rosa, Mar Martínez, María, Garcia Cubillas, Miriam D, Ramírez‐Manent, Ignacio, Gallardo‐Alfaro, Laura

“…Background Gut microbiota and its by‐products are increasingly recognized as having a decisive role in cardiovascular diseases. The aim is to study the…”
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TRAF3 alterations are frequent in del‐3′IGH chronic lymphocytic leukemia patients and define a specific subgroup with adverse clinical features by Pérez‐Carretero, Claudia, Hernández‐Sánchez, María, González, Teresa, Quijada‐Álamo, Miguel, Martín‐Izquierdo, Marta, Santos‐Mínguez, Sandra, Miguel‐García, Cristina, Vidal, María‐Jesús, García‐De‐Coca, Alfonso, Galende, Josefina, Pardal, Emilia, Aguilar, Carlos, Vargas‐Pabón, Manuel, Dávila, Julio, Gascón‐Y‐Marín, Isabel, Hernández‐Rivas, José‐Ángel, Benito, Rocío, Hernández‐Rivas, Jesús‐María, Rodríguez‐Vicente, Ana‐Eugenia

“…Interstitial 14q32 deletions involving IGH gene are infrequent events in chronic lymphocytic leukemia (CLL), affecting less than 5% of patients. To date,…”
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Clinical, biological, and prognostic implications of SF3B1 co-occurrence mutations in very low/low- and intermediate-risk MDS patients by Janusz, Kamila, Izquierdo, Marta Martín, Cadenas, Félix López, Ramos, Fernando, Sánchez, Jesús María Hernández, Lumbreras, Eva, Robledo, Cristina, del Real, Javier Sánchez, Caballero, Juan Carlos, Collado, Rosa, Bernal, Teresa, Pedro, Carme, Insunza, Andrés, de Paz, Raquel, Xicoy, Blanca, Salido, Eduardo, García, Joaquín Sánchez, Mínguez, Sandra Santos, García, Cristina Miguel, Muñoz, Ana María Simón, Barba, Mercedes Sánchez, Rivas, Jesús María Hernández, Abáigar, María, Campelo, María Díez

“…SF3B1 is a highly mutated gene in myelodysplastic syndrome (MDS) patients, related to a specific subtype and parameters of good prognosis in MDS without excess…”
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Gut microbiota composition and arterial stiffness measured by pulse wave velocity: case–control study protocol (MIVAS study) by Salvado, Rita, Santos-Minguez, Sandra, Agudo-Conde, Cristina, Lugones-Sanchez, Cristina, Cabo-Laso, Angela, Mª Hernandez-Sanchez, Jesus, Benito, Rocio, Rodriguez-Sanchez, Emiliano, Gomez-Marcos, Manuel A, Hernandez-Rivas, Jesus M, Guimarães Cunha, Pedro, Garcia-Ortiz, Luis, Investigators, MIVAS

“…IntroductionIntestinal microbiota is arising as a new element in the physiopathology of cardiovascular diseases. A healthy microbiota includes a balanced…”
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ZMYM3 Mutations Cooperate with NOTCH1 Alterations, Reduce Histone H4 Acetylation and Promote Apoptosis Evasion in Chronic Lymphocytic Leukemia by Rodríguez-Sánchez, Alberto, Quijada Álamo, Miguel, Perez Carretero, Claudia, Corchete Sanchez, Luis Antonio, Villaverde Ramiro, Angela, Miguel-García, Cristina, Santos-Mínguez, Sandra, Valls, Julio Davila, Garcia de Coca, Alfonso, Olazabal, Julio, Benito Sanchez, Maria Rocio, Rodriguez, Ana E., Hernández-Rivas, Jesús María

“…Introduction: Recent next-generation sequencing (NGS) studies have identified up to 200 recurrently mutated genes in chronic lymphocytic leukemia (CLL), the…”
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Mutually-Exclusive Pathways between IKZF1plus and RAS Mutations and TP53 double-Hit Alterations Lead Relapse in B-Other, Ph-like and Hyperdiploidy Genetic Groups in Adult B-Cell Acute Lymphoblastic Leukemia by Navas Acosta, Josgrey Del Valle Del Valle, González, Teresa, Serramito-Gómez, Inmaculada, Villaverde Ramiro, Angela, Miguel-García, Cristina, Santos-Mínguez, Sandra, Ribera, Jordi, Granada, Isabel, Morgades, Mireia, Sanchez, Ricardo, Such, Esperanza, Barrera, Susana, Ciudad, Juana, Orfao, Alberto, Valls, Julio Davila, De Las Heras, Natalia, Fuster, José, Garcia de Coca, Alfonso, Labrador, Jorge, Queizan Hernandez, Jose Antonio, Mendoza, María Carmen, Riesco, Susana, Martín, Sandra, Ribera, Josep-Maria, Benito Sanchez, Maria Rocio, Hernández-Rivas, Jesús María

“…Introduction: Adult B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a hematologic malignancy characterized by a high genetic heterogeneity and high…”
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Mutually-Exclusive Pathways between IKZF1 plus and RAS Mutations and TP53 double-Hit Alterations Lead Relapse in B-Other, Ph-like and Hyperdiploidy Genetic Groups in Adult B-Cell Acute Lymphoblastic Leukemia by Navas Acosta, Josgrey Del Valle Del Valle, González, Teresa, Serramito-Gómez, Inmaculada, Villaverde Ramiro, Angela, Miguel-García, Cristina, Santos-Mínguez, Sandra, Ribera, Jordi, Granada, Isabel, Morgades, Mireia, Sanchez, Ricardo, Such, Esperanza, Barrera, Susana, Ciudad, Juana, Orfao, Alberto, Valls, Julio Davila, De Las Heras, Natalia, Fuster, José, Garcia de Coca, Alfonso, Labrador, Jorge, Queizan Hernandez, Jose Antonio, Mendoza, María Carmen, Riesco, Susana, Martín, Sandra, Ribera, Josep-Maria, Benito Sanchez, Maria Rocio, Hernández-Rivas, Jesús María

“…Introduction: Adult B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a hematologic malignancy characterized by a high genetic heterogeneity and high…”
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IKZF1 Deletions Are Markers of Treatment Resistance in Adult Ph-Negative B-Cell Acute Lymphoblastic Leukemia Patients Treated within the Ongoing Risk-Adapted Pethema LAL19 Trial by Ribera, Jordi, Granada, Isabel, González, Teresa, Morgades, Mireia, Garcia, Olga, Sanchez, Ricardo, Such, Esperanza, Barrena, Susana, Ciudad, Juana, Soriano, Beatriz, Benito, Rocio, Avetisyan, Gayane, Lumbreras, Eva, Miguel-García, Cristina, Santos-Mínguez, Sandra, Zamora, Lurdes, Mallo, Mar, González-Gil, Celia, Genescà, Eulàlia, Lopes, Thaysa, Hernández-Rivas, Jesus Maria, Orfao, Alberto, Ribera, Josep-Maria

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Identification By Whole Exome Sequencing of the Molecular Defect in a Novel Gene Related to Glycosylation in Two Unrelated Families with Syndromic Macrothrombocytopenia by Marín-Quílez, Ana, Vuelta, Elena, Santos-Mínguez, Sandra, Miguel-García, Cristina, Ruíz-Sala, Pedro, Palma-Barqueros, Veronica, Díaz-Ajenjo, Lorena, Serramito-Gómez, Inmaculada, Peñarrubia, Maria Jesús, Pardal, Emilia, Castiñeiras-Ramos, Daisy, González-Porras, José Ramón, Rivera, Jose, Benito, Rocio, Hernández-Rivas, Jesus Maria, García-Tuñón, Ignacio, Bastida, Jose Maria

“…Introduction Inherited thrombocytopenias (ITs) are a heterogeneous group of rare platelet disorders. which lead not only to increased bleeding, but also to…”
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Sequential Study By RNA-Seq Shows a Reduction in Inflammation and a Cell Cycle Activation in T-Lymphocytes from Myelodysplastic Syndrome with Del(5q) after Lenalidomide Treatment in Patients Included in the “Sintra-REV” Clinical Trial by Del Rey, Mónica, Corchete, Luis A, González, Teresa, López Cadenas, Félix, Lumbreras, Eva, Martín Izquierdo, Marta, Santos-Mínguez, Sandra, Toribio, Sofía M, Xicoy, Blanca, Sánchez-García, Joaquín, Bernal, Teresa, Sanz, Guillermo F, Nomdedeu, Benet, Fenaux, Pierre, Hernández Rivas, Jesús M, Diez-Campelo, Maria

“…Introduction: Lenalidomide is a potent drug with pleiotropic effects in patients with myelodysplastic syndrome (MDS) with deletion of the long arm of…”
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Clinical and Biological Impact of TP53 Alterations in Del(11q) Chronic Lymphocytic Leukemia by Pérez Carretero, Claudia, Quijada Álamo, Miguel, Hernandez-Sanchez, Maria, Rodriguez, Ana E., Herrero, Ana B, Hernández-Sánchez, Jesus M, Martín Izquierdo, Marta, González, Teresa, Santos-Mínguez, Sandra, Miguel-García, Cristina, Rubio-Martínez, Araceli, García de Coca, Alfonso, Dávila, Julio, Hernandez, Jose-Angel, Benito, Rocio, Ordóñez, José Luis, Hernández-Rivas, Jesus Maria

“…Large-scale next-generation sequencing (NGS) studies have suggested common patterns of co-occurrence or mutual exclusivity between genetic alterations in…”
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Genomic Instability and a Preferential Involvement of Ras Pathway in the Myelodysplastic Syndromes Evolution to Secondary Acute Myeloid Leukemia by Martín Izquierdo, Marta, Abáigar, María, Hernández-Sánchez, Jesus M, López Cadenas, Félix, Ramos, Fernando, Lumbreras, Eva, Madinaveitia-Ochoa, Andrés, Megido, Marta, Labrador, Jorge, Sánchez del Real, Javier, Olivier, Carmen, Dávila, Julio, Aguilar, Carlos, Rodríguez, Juan Nicolás, Martín-Nuñez, Guillermo, Santos-Mínguez, Sandra, Benito, Rocio, Del Cañizo, Consuelo, Díez-Campelo, María, Hernández-Rivas, Jesús María

“…Myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) are hematological disorders at high risk of progression to acute myeloid leukemia…”
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Chronic Lymphocytic Leukemia Patients with IGH Rearrangements Are Characterized By a Distinct Genetic Landscape with Prognostic Implications by Pérez Carretero, Claudia, Hernandez-Sanchez, Maria, Gonzalez, Teresa, Quijada Álamo, Miguel, Martín Izquierdo, Marta, Hernández-Sánchez, Jesus M, Santos-Mínguez, Sandra, Vidal, María-Jesús, García de Coca, Alfonso, Aguilar, Carlos, Vargas-Pabón, Manuel, Alonso, Sara, Sierra, Magdalena, Rubio-Martínez, Araceli, Dávila, Julio, Díaz-Valdés, José R, Queizan, Jose Antonio, Hernandez-Rivas, Jose Angel, Mateos, Maria-Victoria, Benito, Rocio, Rodriguez, Ana E., Hernández-Rivas, Jesús-María

“…Background: Chromosome 14q32 rearrangements involving the immunoglobulin heavy chain gene (IGH) affect less than 5% of chronic lymphocytic leukemia (CLL)…”
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TRAF3 alterations are frequent in del-3'IGH chronic lymphocytic leukemia patients and define a specific subgroup with adverse clinical features by Pérez-Carretero, Claudia, Hernández-Sánchez, María, González, Teresa, Quijada-Álamo, Miguel, Martín-Izquierdo, Marta, Santos-Mínguez, Sandra, Miguel-García, Cristina, Vidal, María-Jesús, García-De-Coca, Alfonso, Galende, Josefina, Pardal, Emilia, Aguilar, Carlos, Vargas-Pabón, Manuel, Dávila, Julio, Gascón-Y-Marín, Isabel, Hernández-Rivas, José-Ángel, Benito, Rocío, Hernández-Rivas, Jesús-María, Rodríguez-Vicente, Ana-Eugenia

“…Interstitial 14q32 deletions involving IGH gene are infrequent events in chronic lymphocytic leukemia (CLL), affecting less than 5% of patients. To date,…”
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Dissecting the role of TP53 alterations in del(11q) chronic lymphocytic leukemia by Quijada‐Álamo, Miguel, Pérez‐Carretero, Claudia, Hernández‐Sánchez, María, Rodríguez‐Vicente, Ana‐Eugenia, Herrero, Ana‐Belén, Hernández‐Sánchez, Jesús‐María, Martín‐Izquierdo, Marta, Santos‐Mínguez, Sandra, del Rey, Mónica, González, Teresa, Rubio‐Martínez, Araceli, García de Coca, Alfonso, Dávila‐Valls, Julio, Hernández‐Rivas, José‐Ángel, Parker, Helen, Strefford, Jonathan C., Benito, Rocío, Ordóñez, José‐Luis, Hernández‐Rivas, Jesús‐María

“…Background Several genetic alterations have been identified as driver events in chronic lymphocytic leukemia (CLL) pathogenesis and oncogenic evolution…”
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