Search Results - "Mévélec, Marie Noelle"

Key Limitations and New Insights Into the Toxoplasma gondii Parasite Stage Switching for Future Vaccine Development in Human, Livestock, and Cats by Mévélec, Marie-Noëlle, Lakhrif, Zineb, Dimier-Poisson, Isabelle

“…Toxoplasmosis is a parasitic disease affecting human, livestock and cat. Prophylactic strategies would be ideal to prevent infection. In a One Health…”
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Engineering and Functional Evaluation of Neutralizing Antibody Fragments Against Congenital Toxoplasmosis by di Tommaso, Anne, Juste, Matthieu O, Lakhrif, Zineb, Mévélec, Marie-Noëlle, Borowczyk, Coraline, Hammeni, Pierre, Désoubeaux, Guillaume, Van Langendonck, Nathalie, Debierre-Grockiego, Françoise, Aubrey, Nicolas, Dimier-Poisson, Isabelle

“…Abstract Maternal-fetal transmission of Toxoplasma gondii tachyzoites acquired during pregnancy has potentially dramatic consequences for the fetus. Current…”
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Co-delivery of PLGA nanoparticles loaded with rSAG1 antigen and TLR ligands: An efficient vaccine against chronic toxoplasmosis by Allahyari, Mojgan, Golkar, Majid, Fard-Esfahani, Pezhman, Dimier-Poisson, Isabelle, Mévélec, Marie-Noëlle

“…Although vaccination is a promising approach for the control of toxoplasmosis, there is currently no commercially available human vaccine. Adjuvants such as…”
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Targeted Delivery of Toxoplasma gondii Antigens to Dendritic Cells Promote Immunogenicity and Protective Efficiency against Toxoplasmosis by Lakhrif, Zineb, Moreau, Alexis, Hérault, Bruno, Di-Tommaso, Anne, Juste, Matthieu, Moiré, Nathalie, Dimier-Poisson, Isabelle, Mévélec, Marie-Noëlle, Aubrey, Nicolas

“…Toxoplasmosis is a major public health problem and the development of a human vaccine is of high priority. Efficient vaccination against requires both a…”
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Nasal administration of recombinant Neospora caninum secreting IL-15/IL-15Rα inhibits metastatic melanoma development in lung by Battistoni, Arthur, Lantier, Louis, di Tommaso, Anne, Ducournau, Céline, Lajoie, Laurie, Samimi, Mahtab, Coënon, Loïs, Rivière, Clément, Epardaud, Mathieu, Hertereau, Leslie, Poupée-Beaugé, Agathe, Rieu, Juliette, Mévélec, Marie-Noëlle, Lee, Gordon Scott, Moiré, Nathalie, Germon, Stephanie, Dimier-Poisson, Isabelle

“…BackgroundMetastases are the leading cause of mortality in many cancer types and lungs are one of the most common sites of metastasis alongside the liver,…”
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Immunological responses induced by a DNA vaccine expressing RON4 and by immunogenic recombinant protein RON4 failed to protect mice against chronic toxoplasmosis by Rashid, Imran, Hedhli, Dorsaf, Moiré, Nathalie, Pierre, Josette, Debierre-Grockiego, Françoise, Dimier-Poisson, Isabelle, Mévélec, Marie Noëlle

“…Highlights ► We produced recombinant RON4 protein and eukaryotic plasmids expressing RON4. ► We immunized CBA/J mice intranasally or intramuscularly. ► Humoral…”
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Specific Cell Targeting by Toxoplasma gondii Displaying Functional Single-Chain Variable Fragment as a Novel Strategy; A Proof of Principle by Aljieli, Muna, Rivière, Clément, Lantier, Louis, Moiré, Nathalie, Lakhrif, Zineb, Boussemart, Anne-France, Cnudde, Thomas, Lajoie, Laurie, Aubrey, Nicolas, Ahmed, Elhadi M, Dimier-Poisson, Isabelle, Di-Tommaso, Anne, Mévélec, Marie-Noëlle

“…holds significant therapeutic potential; however, its nonspecific invasiveness results in off-target effects. The purpose of this study is to evaluate whether…”
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The antigen-specific response to Toxoplasma gondii profilin, a TLR11/12 ligand, depends on its intrinsic adjuvant properties by Hedhli, Dorsaf, Moiré, Nathalie, Akbar, Haroon, Laurent, Fabrice, Héraut, Bruno, Dimier-Poisson, Isabelle, Mévélec, Marie Noëlle

“…Agonists that activate Toll-like receptors (TLR) are potential vaccine adjuvants. In particular, Toxoplasma gondii profilin (TgPRF) is recognized by TLR11/12…”
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Neospora caninum: a new class of biopharmaceuticals in the therapeutic arsenal against cancer by Lantier, Louis, Poupée-Beaugé, Agathe, di Tommaso, Anne, Ducournau, Céline, Epardaud, Mathieu, Lakhrif, Zineb, Germon, Stéphanie, Debierre-Grockiego, Françoise, Mévélec, Marie-Noëlle, Battistoni, Arthur, Coënon, Loïs, Deluce-Kakwata-Nkor, Nora, Velge-Roussel, Florence, Beauvillain, Céline, Baranek, Thomas, Lee, Gordon Scott, Kervarrec, Thibault, Touzé, Antoine, Moiré, Nathalie, Dimier-Poisson, Isabelle

“…BackgroundMicroorganisms that can be used for their lytic activity against tumor cells as well as inducing or reactivating antitumor immune responses are a…”
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The MIC3 Gene of Toxoplasma gondii Is a Novel Potent Vaccine Candidate against Toxoplasmosis by Ismael, Alaa Bassuny, Sekkai, Dalila, Collin, Christine, Bout, Daniel, Mévélec, Marie-Noëlle

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Evaluation of protective effect of DNA vaccination with genes encoding antigens GRA4 and SAG1 associated with GM-CSF plasmid, against acute, chronical and congenital toxoplasmosis in mice by Mévélec, Marie-Noëlle, Bout, Daniel, Desolme, Benoît, Marchand, Hervé, Magné, Rémy, Bruneel, Odile, Buzoni-Gatel, Dominique

“…To develop a multiantigenic vaccine against toxoplasmosis, two Toxoplasma gondii antigens, SAG1 and GRA4 selected on the basis of previous immunological and…”
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Mic1-3 Knockout of Toxoplasma gondii Is a Successful Vaccine against Chronic and Congenital Toxoplasmosis in Mice by Ismael, Alaa Bassuny, Dimier-Poisson, Isabelle, Lebrun, Maryse, Dubremetz, Jean-François, Bout, Daniel, Mévélec, Marie-Noëlle

“…BackgroundWe evaluated a new vaccine, Mic1-3KO, against both chronic and congenital toxoplasmosis in mice. Mic1-3KO is a mutant strain of Toxoplasma gondii RH…”
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Protection against Lethal Neospora caninum Infection in Mice Induced by Heterologous Vaccination with a mic1 mic3 Knockout Toxoplasma gondii Strain by Penarete-Vargas, Diana Marcela, Mévélec, Marie Noelle, Dion, Sarah, Sèche, Edouard, Dimier-Poisson, Isabelle, Fandeur, Thierry

“…Neospora caninum and Toxoplasma gondii are closely related, obligate intracellular parasites infecting a wide range of vertebrate hosts and causing abortion…”
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Exploration and Modulation of Antibody Fragment Biophysical Properties by Replacing the Framework Region Sequences by Cnudde, Thomas, Lakhrif, Zineb, Bourgoin, Justine, Boursin, Fanny, Horiot, Catherine, Henriquet, Corinne, di Tommaso, Anne, Juste, Matthieu Olivier, Jiacomini, Isabella Gizzi, Dimier-Poisson, Isabelle, Pugnière, Martine, Mévélec, Marie-Nöelle, Aubrey, Nicolas

“…In order to increase the successful development of recombinant antibodies and fragments, it seems fundamental to enhance their expression and/or biophysical…”
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Protective immunity against Toxoplasma challenge in mice by coadministration of T. gondii antigens and Eimeria profilin-like protein as an adjuvant by Hedhli, Dorsaf, Dimier-Poisson, Isabelle, Judge, John W, Rosenberg, Barnett, Mévélec, Marie Noëlle

“…Abstract Toll-like receptor (TLR) ligands are attractive adjuvant candidates in vaccine development. Eimeria tenella profilin-like protein has recently been…”
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Mic1-3 Knockout Toxoplasma gondii is a good candidate for a vaccine against T. gondii-induced abortion in sheep by Mévélec, Marie-Noëlle, Ducournau, Céline, Bassuny Ismael, Alaa, Olivier, Michel, Sèche, Edouard, Lebrun, Maryse, Bout, Daniel, Dimier-Poisson, Isabelle

“…This study assessed the effectiveness of a mutant strain of Toxoplasma gondii (RH strain) lacking the mic1 and mic3 genes (Mic1-3KO) against Toxoplasma…”
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Further analysis of protection induced by the MIC3 DNA vaccine against T. gondii : CD4 and CD8 T cells are the major effectors of the MIC3 DNA vaccine-induced protection, both Lectin-like and EGF-like domains of MIC3 conferred protection by Ismael, Alaa Bassuny, Hedhli, Dorsaf, Cérède, Odile, Lebrun, Maryse, Dimier-Poisson, Isabelle, Mévélec, Marie-Noëlle

“…Abstract The present study was conducted mainly to evaluate the contribution of the cellular and the humoral responses in protection conferred by the MIC3 DNA…”
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Protective Mucosal Th2 Immune Response against Toxoplasma gondii by Murine Mesenteric Lymph Node Dendritic Cells by Dimier-Poisson, Isabelle, Aline, Fleur, Mévélec, Marie-Noëlle, Beauvillain, Céline, Buzoni-Gatel, Dominique, Bout, Daniel

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Induction of protective immunity against toxoplasmosis in mice by immunization with Toxoplasma gondii RNA by Dimier-Poisson, Isabelle, Aline, Fleur, Bout, Daniel, Mévélec, Marie-Noëlle

“…Toxoplasma gondii enters the mucosal surfaces of the host, and so immunity at these sites is of major interest. Due to the compartmentalization of the immune…”
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Induction of protective immunity against toxoplasmosis in mice by DNA immunization with a plasmid encoding Toxoplasma gondii GRA4 gene by Desolme, Benoı̂t, Mévélec, Marie-Noëlle, Buzoni-Gatel, Dominique, Bout, Daniel

“…GRA4 is a dense granule protein of Toxoplasma gondii that is a candidate for vaccination against this parasite. We have inserted the entire coding sequence of…”
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