Search Results - "Ménard, Vincent"
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Modulation of the UGT2B7 enzyme activity by C-terminally truncated proteins derived from alternative splicing
Published in Drug metabolism and disposition (01-12-2013)“…The enzyme UGT2B7 is one of the most active UDP-glucuronosyltransferases (UGTs) involved in drug metabolism and in maintaining homeostasis of endogenous…”
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2
Sleep habits, academic performance, and the adolescent brain structure
Published in Scientific reports (09-02-2017)“…Here we report the first and most robust evidence about how sleep habits are associated with regional brain grey matter volumes and school grade average in…”
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3
Circulating Estrogens in Endometrial Cancer Cases and Their Relationship with Tissular Expression of Key Estrogen Biosynthesis and Metabolic Pathways
Published in The journal of clinical endocrinology and metabolism (01-06-2010)“…Background: Endometrial cancer is the most common gynecological malignancy. Estrogen exposure is strongly associated with endometrial cancer. Whereas this…”
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4
Production of a new tissue-engineered adipose substitute from human adipose-derived stromal cells
Published in Biomaterials (2007)“…Abstract Adipose tissue is an accessible and abundant source of mesenchymal stem cells for soft-tissue reconstruction. In an attempt to create a novel,…”
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5
Transcriptional diversity at the UGT2B7 locus is dictated by extensive pre-mRNA splicing mechanisms that give rise to multiple mRNA splice variants
Published in Pharmacogenetics and genomics (01-10-2011)“…OBJECTIVEUGT2B7 is a key member of the UDP-glucuronosyltransferase (UGT) family that participates in glucuronidation of endogenous compounds and…”
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6
Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population
Published in Human mutation (01-04-2009)“…The UDP-glucuronosyltransferase UGT1 locus is composed of nine exon 1s, each flanked by a unique promoter region, and common exons (2, 3, 4, and the…”
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7
Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism
Published in Human mutation (01-09-2009)“…UGT2B17 and UGT2B28 are among the most commonly deleted genes in humans and encode members of the uridine diphosphate (UDP)-glucuronosyltransferase 2B (UGT2B)…”
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8
Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation
Published in Pharmacogenetics and genomics (01-03-2010)“…BACKGROUND AND AIMSUGT2B4 is a member of the UDP-glucuronosyltransferase (UGT) superfamily, a major detoxifying system in humans. UGT2B4 is involved in bile…”
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Expression of UGT2B7 is driven by two mutually exclusive promoters and alternative splicing in human tissues: changes from prenatal life to adulthood and in kidney cancer
Published in Pharmacogenetics and genomics (01-12-2013)“…OBJECTIVEUDP-glucuronosyltransferase 2B7 (UGT2B7) plays a major detoxification role in commonly prescribed drugs and endogenous lipophilic molecules…”
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10
A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3
Published in Pharmacogenetics and genomics (01-07-2007)“…UGT1A3 is one of the most efficient at conjugating estrone, a precursor for biosynthesis of estradiol in peripheral tissues. We established the genetic…”
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11
Impact of long-lasting moderate-intensity stage cycling event on cardiac function in young female athletes: A case study
Published in PloS one (04-10-2022)“…PurposeEffects of intense and/or prolonged exercise have been studied extensively in male athletes. Nevertheless, data are scare on the effect of long duration…”
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12
Impact of long-lasting moderate-intensity stage cycling event on cardiac function in young female athletes: A case study
Published in PloS one (04-10-2022)“…Purpose Effects of intense and/or prolonged exercise have been studied extensively in male athletes. Nevertheless, data are scare on the effect of long…”
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13
Non-Specific Low Back Pain: An Inductive Exploratory Analysis through Factor Analysis and Deep Learning for Better Clustering
Published in Brain sciences (01-06-2023)“…Non-specific low back pain (NSLBP) is a significant and pervasive public health issue in contemporary society. Despite the widespread prevalence of NSLBP, our…”
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Corrigendum: Cardiac function and autonomic cardiac function during a multi-stage cycling event: a brief report
Published in Frontiers in sports and active living (2024)“…[This corrects the article DOI: 10.3389/fspor.2024.1356577.]…”
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Cardiac function and autonomic cardiac function during a multi-stage cycling event: a brief report
Published in Frontiers in sports and active living (29-07-2024)“…Prolonged and repeated exercise performed during an ultra-endurance event can induce general and cardiac fatigue known as exercise-induced cardiac fatigue. Our…”
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Enhanced Pulmonary Artery Radiodensity in Pulmonary Arterial Hypertension: A Sign of Early Calcification?
Published in American journal of respiratory and critical care medicine (15-03-2019)“…[...]mean PApwa was increased in all PAH subtypes, and this observation could not be explained by differences in hematologic parameters or aortic radiodensity…”
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Cardiac Events in World-class Athletes: An Internet-based Study
Published in Medicine and science in sports and exercise (19-07-2022)Get full text
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UGT genomic diversity: beyond gene duplication
Published in Drug metabolism reviews (01-02-2010)“…The human uridine diphospho (UDP)-glucuronosyltransferase (UGT) superfamily comprises enzymes responsible for a major biotransformation phase II pathway: the…”
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Cardiac Events in World-Class Athletes: An Internet-Based Study
Published in Medicine and science in sports and exercise (01-12-2022)“…PURPOSEThis study aimed at assessing the prevalence of adverse cardiac events, as identified in the media, in world-class athletes according to their sex and…”
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What a good boy! Deciphering the efficiency of detection dogs
Published in Frontiers in analytical science (30-08-2022)“…Dogs have a powerful olfactory system, which is used in many areas of the police and military to detect drugs, human remains, and explosives, among other…”
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