Search Results - "Ménade, Marie"

Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation by Trempe, Jean-François, Sauvé, Véronique, Grenier, Karl, Seirafi, Marjan, Tang, Matthew Y., Ménade, Marie, Al-Abdul-Wahid, Sameer, Krett, Jonathan, Wong, Kathy, Kozlov, Guennadi, Nagar, Bhushan, Fon, Edward A., Gehring, Kalle

“…Mutations in the PARK2 (parkin) gene are responsible for an autosomal recessive form of Parkinson's disease. The parkin protein is a RING-in-between-RING E3…”
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Single-particle electron microscopy structure of UDP-glucose:glycoprotein glucosyltransferase suggests a selectivity mechanism for misfolded proteins by Calles-Garcia, Daniel, Yang, Meng, Soya, Naoto, Melero, Roberto, Ménade, Marie, Ito, Yukishige, Vargas, Javier, Lukacs, Gergely L., Kollman, Justin M., Kozlov, Guennadi, Gehring, Kalle

“…The enzyme UDP-glucose:glycoprotein glucosyltransferase (UGGT) mediates quality control of glycoproteins in the endoplasmic reticulum by attaching glucose to…”
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Local Activation of Yeast ASH1 mRNA Translation through Phosphorylation of Khd1p by the Casein Kinase Yck1p by Paquin, Nicolas, Ménade, Marie, Poirier, Guillaume, Donato, Damiane, Drouet, Emmanuel, Chartrand, Pascal

“…In S. cerevisiae, the ASH1 mRNA is localized at the bud tip of late-anaphase cells, resulting in the exclusive sorting of Ash1p to the daughter cell nucleus…”
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Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein by Kozlov, Guennadi, Ménade, Marie, Rosenauer, Angelika, Nguyen, Long, Gehring, Kalle

“…MLLE (previously known as PABC) is a peptide-binding domain that is found in poly(A)-binding protein (PABP) and EDD (E3 isolated by differential display), a…”
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High-Throughput Screening for Ligands of the HEPN Domain of Sacsin by Li, Xinlu, Ménade, Marie, Kozlov, Guennadi, Hu, Zheping, Dai, Zheng, McPherson, Peter S, Brais, Bernard, Gehring, Kalle

“…Sacsin is a large protein implicated in the neurodevelopmental and neurodegenerative disease autosomal recessive spastic ataxia of Charlevoix-Saguenay…”
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Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations by Ménade, Marie, Kozlov, Guennadi, Trempe, Jean-François, Pande, Harshit, Shenker, Solomon, Wickremasinghe, Sihara, Li, Xinlu, Hojjat, Hamed, Dicaire, Marie-Josée, Brais, Bernard, McPherson, Peter S., Wong, Michael J.H., Young, Jason C., Gehring, Kalle

“…Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disease that is caused by mutations in the SACS gene. The product of…”
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Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family by Trempe, Jean-François, Šašková, Klára Grantz, Sivá, Monika, Ratcliffe, Colin D. H., Veverka, Václav, Hoegl, Annabelle, Ménade, Marie, Feng, Xin, Shenker, Solomon, Svoboda, Michal, Kožíšek, Milan, Konvalinka, Jan, Gehring, Kalle

“…The eukaryotic Ddi1 family is defined by a conserved retroviral aspartyl protease-like (RVP) domain found in association with a ubiquitin-like (UBL) domain…”
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Sacsin, mutated in the ataxia ARSACS, regulates intermediate filament assembly and dynamics by Gentil, Benoit J., Lai, Gia-Thanh, Menade, Marie, Larivière, Roxanne, Minotti, Sandra, Gehring, Kalle, Chapple, J.-Paul, Brais, Bernard, Durham, Heather D.

“…ABSTRACT Loss of sacsin, a large 520 kDa multidomain protein, causes autosomal recessive spastic ataxia of the Charlevoix‐Saguenay, one of the most common…”
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Structural and functional studies of Sacsin by Menade, Marie, Kozlov, Guennadi, Gehring, Kalle

“…Abstract only Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an early-onset neurodegenerative disorder caused by mutations in the SACS…”
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Structure of parkin reveals the mechanism of autoinhibition by Seirafi, Marjan, Trempe, Jean-Francois, Sauve, Veronique, Kozlov, Guennadi, Menade, Marie, Nagar, Bhushan, Gehring, kalle

“…Abstract only Mutations in the gene park2 that codes for a RING-In-Between-RING (RBR) E3 ubiquitin ligase are responsible for an autosomal recessive form of…”
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Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase by Matta-Camacho, Edna, Kozlov, Guennadi, Menade, Marie, Gehring, Kalle

“…UBR5 ubiquitin ligase (also known as EDD, Rat100 or hHYD) is a member of the E3 protein family of HECT (homologous to E6‐AP C‐terminus) ligases as it contains…”
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