Search Results - "Mély, Stephane"
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Emergence of Zaire Ebola Virus Disease in Guinea
Published in The New England journal of medicine (09-10-2014)“…In March 2014, an outbreak of Ebola virus disease associated with a high fatality rate was identified in Guinea, with evidence of ongoing person-to-person…”
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Unique human immune signature of Ebola virus disease in Guinea
Published in Nature (London) (05-05-2016)“…Fatal Ebola virus disease is characterized by a high proportion of CD4 + and CD8 + T cells expressing the inhibitory molecules CTLA-4 and PD-1, correlating…”
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Long-lasting severe immune dysfunction in Ebola virus disease survivors
Published in Nature communications (24-07-2020)“…Long-term follow up studies from Ebola virus disease (EVD) survivors (EBOV_S) are lacking. Here, we evaluate immune and gene expression profiles in 35 Guinean…”
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4
Activation of cGAS/STING pathway upon paramyxovirus infection
Published in iScience (25-06-2021)“…During inflammatory diseases, cancer, and infection, the cGAS/STING pathway is known to recognize foreign or self-DNA in the cytosol and activate an innate…”
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Detection of Crimean-Congo haemorrhagic fever virus in Hyalomma marginatum ticks, southern France, May 2022 and April 2023
Published in Euro surveillance : bulletin européen sur les maladies transmissibles (08-02-2024)“…Crimean-Congo haemorrhagic fever (CCHF), a potentially severe zoonotic viral disease causing fever and haemorrhagic manifestations in humans. As the…”
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Crimean-Congo hemorrhagic fever virus replication imposes hyper-lipidation of MAP1LC3 in epithelial cells
Published in Autophagy (02-10-2020)“…Crimean-Congo hemorrhagic fever virus (CCHFV) is a virus that causes severe liver dysfunctions and hemorrhagic fever, with high mortality rate. Here, we show…”
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Lassa fever in Benin: description of the 2014 and 2016 epidemics and genetic characterization of a new Lassa virus
Published in Emerging microbes & infections (01-01-2020)“…We report two outbreaks of Lassa fever that occurred in Benin in 2014 and 2016 with 20 confirmed cases and 50% (10/20) mortality. Benin was not previously…”
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Heparan sulfate-dependent enhancement of henipavirus infection
Published in mBio (10-03-2015)“…Nipah virus and Hendra virus are emerging, highly pathogenic, zoonotic paramyxoviruses that belong to the genus Henipavirus. They infect humans as well as…”
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Natural History of Sudan ebolavirus to Support Medical Countermeasure Development
Published in Vaccines (Basel) (16-06-2022)“…Sudan ebolavirus (SUDV) is one of four members of the Ebolavirus genus known to cause Ebola Virus Disease (EVD) in humans, which is characterized by…”
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A 40 months follow-up of Ebola virus disease survivors in Guinea (Postebogui) reveals longterm detection of Ebola viral RNA in semen and breast milk
Published in Open forum infectious diseases (08-11-2019)“…Abstract Background With the increasing frequency and impact of Ebola virus disease (EVD) outbreaks illustrated by recent epidemics, good knowledge on extent…”
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Characterization and analytical validation of a new antigenic rapid diagnostic test for Ebola virus disease detection
Published in PLoS neglected tropical diseases (01-01-2020)“…Hemorrhagic fever outbreaks are difficult to diagnose and control in part because of a lack of low-cost and easily accessible diagnostic structures in…”
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A 40 months follow-up of Ebola virus disease survivors in Guinea (Postebogui) reveals long-term detection of Ebola viral Ribonucleic Acid in semen and breast milk
Published in Open forum infectious diseases (08-11-2019)“…Background: With the increasing frequency and impact of Ebola virus disease (EVD) outbreaks illustrated by recent epidemics, a good understanding of the extent…”
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13
Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report
Published in The New England journal of medicine (16-04-2014)“…: In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a…”
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14
Temporal and spatial analysis of the 2014–2015 Ebola virus outbreak in West Africa
Published in Nature (London) (06-08-2015)“…Analysis of 179 new Ebola virus sequences from patient samples collected in Guinea between March 2014 and January 2015 shows how different lineages evolved and…”
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Crimean-Congo hemorrhagic fever virus replication imposes hyper-lipidation of MAP1LC3 in epithelial cells
Published in Autophagy (02-10-2020)Get full text
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16
Analysis of Diagnostic Findings From the European Mobile Laboratory in Guéckédou, Guinea, March 2014 Through March 2015
Published in The Journal of infectious diseases (15-10-2016)“…Background. A unit of the European Mobile Laboratory (EMLab) consortium was deployed to the Ebola virus disease (EVD) treatment unit in Guéckédou, Guinea, from…”
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A 40-Month Follow-Up of Ebola Virus Disease Survivors in Guinea (PostEbogui) Reveals Long-Term Detection of Ebola Viral Ribonucleic Acid in Semen and Breast Milk
Published in Open forum infectious diseases (01-12-2019)“…With the increasing frequency and impact of Ebola virus disease (EVD) outbreaks illustrated by recent epidemics, a good understanding of the extent of viral…”
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Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea
Published in PLoS medicine (01-03-2016)“…Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at…”
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Correction: Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea
Published in PLoS medicine (01-04-2016)“…[This corrects the article DOI: 10.1371/journal.pmed.1001967.]…”
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Experimental Treatment with Favipiravir for Ebola Virus Disease
Published in PLoS medicine (01-03-2016)“…Background Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola…”
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