Search Results - "Médici, Rosario"
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Synthetic Activity of Recombinant Whole Cell Biocatalysts Containing 2‐Deoxy‐D‐ribose‐5‐phosphate Aldolase from Pectobacterium atrosepticum
Published in Chembiochem : a European journal of chemical biology (05-07-2022)“…In nature 2‐deoxy‐D‐ribose‐5‐phosphate aldolase (DERA) catalyses the reversible formation of 2‐deoxyribose 5‐phosphate from D‐glyceraldehyde 3‐phosphate and…”
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Biological production of monoethanolamine by engineered Pseudomonas putida S12
Published in Journal of biotechnology (10-09-2013)“…•A new engineered strain of P. putida S12 was constructed for the production of monoethanolamine.•Growth inhibition was observed above 100mM of MEA.•P. putida…”
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A comparative study on phosphotransferase activity of acid phosphatases from Raoultella planticola and Enterobacter aerogenes on nucleosides, sugars, and related compounds
Published in Applied microbiology and biotechnology (01-04-2014)“…Natural and modified nucleoside-5′-monophosphates and their precursors are valuable compounds widely used in biochemical studies. Bacterial nonspecific acid…”
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Use of Citrobacter koseri whole cells for the production of arabinonucleosides: A larger scale approach
Published in Process biochemistry (1991) (01-12-2012)“…► C. koseri cells catalyzed the transglycosylation of arabinonucleosides. ► Fludarabine, vidarabine and diaminopurine arabinoside were obtained in good yields…”
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5
Discovery and Engineering of an Aldehyde Tolerant 2-deoxy-D-ribose 5-phosphate Aldolase (DERA) from Pectobacterium atrosepticum
Published in Catalysts (01-08-2020)“…DERA (2-Deoxy-D-ribose 5-phosphate aldolase) is the only known aldolase that accepts two aldehyde substrates, which makes it an attractive catalyst for the…”
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A High-Throughput Screening Assay for Amino Acid Decarboxylase Activity
Published in Advanced synthesis & catalysis (01-09-2011)“…The development of sensitive and easy‐to‐apply high‐throughput screening methods is a common need in modern biocatalysis. With these powerful analytical tools…”
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Biocatalysed halogenation of nucleobase analogues
Published in Biotechnology letters (01-10-2011)“…The synthesis of halogenated nucleosides and nucleobases is of interest due to their chemical and pharmacological applications. Herein, the enzymatic…”
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Synthesis of 9-β-d-arabinofuranosylguanine by combined use of two whole cell biocatalysts
Published in Bioorganic & medicinal chemistry letters (01-08-2009)“…The synthesis of the anti leukemic agent 9-β-d-arabinofuranosylguanine employing two whole cell biocatalysts is reported. Unlike the preparation of other…”
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Arthrobacter oxydans as a biocatalyst for purine deamination
Published in FEMS microbiology letters (01-12-2008)“…Deaminases are enzymes that catalyze the hydrolysis of amino groups of nucleosides or their bases. Because these enzymes play important roles in nucleotide…”
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Rhodococcus strains as source for ene-reductase activity
Published in Applied microbiology and biotechnology (01-07-2018)“…Rhodococcus strains are ubiquitous in nature and known to metabolise a wide variety of compounds. At the same time, asymmetric reduction of C=C bonds is…”
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Biocatalytic approaches applied to the synthesis of nucleoside prodrugs
Published in Biotechnology advances (01-09-2015)“…Nucleosides are valuable bioactive molecules, which display antiviral and antitumour activities. Diverse types of prodrugs are designed to enhance their…”
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Enzymatic hydration activity assessed by selective spectrophotometric detection of alcohols: A novel screening assay using oleate hydratase as a model enzyme
Published in Biotechnology journal (01-06-2014)“…Hydroxy fatty acids (HFAs) are high‐added‐value compounds, which are incorporated in polymers, lubricants, emulsifiers and stabilizers and have potential…”
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Coupled biocatalysts applied to the synthesis of nucleosides
Published in Nucleic Acids Symposium Series (2008)“…Abstract Biocatalytic procedures offer a good alternative to the chemical synthesis of nucleosides since biocatalyzed reactions are regio- and stereoselective…”
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