Search Results - "Médevielle, François"
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1
Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny
Published in eLife (05-10-2021)“…Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know little about its biological…”
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2
The on/off of Pax6 controls the tempo of neuronal differentiation in the developing spinal cord
Published in Developmental biology (15-05-2007)“…During neurogenesis, complex networks of genes act sequentially to control neuronal differentiation. In the neural tube, the expression of Pax6, a…”
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3
A long range distal enhancer controls temporal fine-tuning of PAX6 expression in neuronal precursors
Published in Developmental biology (15-04-2018)“…Proper embryonic development relies on a tight control of spatial and temporal gene expression profiles in a highly regulated manner. One good example is the…”
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4
Control of G 2 Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex
Published in The Journal of neuroscience (15-02-2023)“…During development, cortical neurons are produced in a temporally regulated sequence from apical progenitors, directly or indirectly, through the production of…”
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5
The CDC25B phosphatase shortens the G2 phase of neural progenitors and promotes efficient neuron production
Published in Development (Cambridge) (15-03-2012)“…During embryonic development, changes in cell cycle kinetics have been associated with neurogenesis. This observation suggests that specific cell cycle…”
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6
Identification of the Amino Acid Subsets Accounting for the Ligand Binding Specificity of a Glutamate Receptor
Published in Neuron (Cambridge, Mass.) (01-11-1996)“…In a situation so far unique among neurotransmitter receptors, glutamate receptors share amino acid sequence similarities with the bacterial periplasmic…”
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7
FGF signalling controls the timing of Pax6 activation in the neural tube
Published in Development (Cambridge) (01-11-2000)“…We have recently demonstrated that Pax6 activation occurs in phase with somitogenesis in the spinal cord. Here we show that the presomitic mesoderm exerts an…”
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Activation of Pax6 depends on somitogenesis in the chick embryo cervical spinal cord
Published in Development (Cambridge) (01-02-1999)“…Pax6 is a paired-type homeobox gene expressed in discrete regions of the central nervous system. In the spinal cord of 7- to 10-somite-stage chicken embryos,…”
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9
Identification of an unexpected link between the Shh pathway and a G2/M regulator, the phosphatase CDC25B
Published in Developmental biology (01-06-2006)“…Sonic hedgehog (Shh) signaling controls numerous aspects of vertebrate development, including proliferation of precursors in different organs. Identification…”
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10
The CDC25B phosphatase shortens the G2 phase of neural progenitors and promotes efficient neuron production
Published in Journal of cell science (15-03-2012)Get full text
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11
Specific regulation of cyclins D1 and D2 by FGF and Shh signaling coordinates cell cycle progression, patterning, and differentiation during early steps of spinal cord development
Published in Developmental biology (15-09-2004)“…In the vertebrate embryo, spinal cord elongation requires FGF signaling that promotes the continuous development of the posterior nervous system by maintaining…”
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12
Control of G2 Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex
Published in The Journal of neuroscience (15-02-2023)“…During development, cortical neurons are produced in a temporally regulated sequence from apical progenitors, directly or indirectly, through the production of…”
Get full text
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13
Function of a key cell cycle regulator, the CDC25B phosphatase, during neurogenesis
Published in Developmental biology (15-07-2008)Get full text
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14
Chicken Neuronal Acetylcholine Receptor α2-Subunit Gene Exhibits Neuron-Specific Expression in the Brain and Spinal Cord of Transgenic Mice
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-1993)“…Transgenic mice carrying the complete structural gene of the α 2 subunit of the chicken neuronal nicotinic acetylcholine receptor (nAChR) and 7 kilobase pairs…”
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15
Identification by differential display of a chicken tolloid-related metalloprotease specifically expressed in the caudal notochord
Published in Mechanisms of development (01-08-2000)“…While the ventralizing factor Sonic hedgehog is expressed in the entire notochord (Development 121 (1995) 2537) the latter displays distinct ventralizing…”
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16
Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor
Published in The EMBO journal (01-04-1996)“…The chick cerebellar kainate (KA) binding protein (KBP), a member of the family of ionotropic glutamate receptors, harbours a glycine‐rich (GxGxxG) motif known…”
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