Search Results - "Månsson, J."

Altered distribution of the gangliosides GM1 and GM2 in Alzheimer's disease by Pernber, Z, Blennow, K, Bogdanovic, N, Månsson, J-E, Blomqvist, M

“…Alzheimer's disease (AD) is a neurodegenerative disorder where β-amyloid tends to aggregate and form plaques. Lipid raft-associated ganglioside GM1 has been…”
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γ-Secretase-dependent amyloid-β is increased in Niemann-Pick type C: A cross-sectional study by MATTSSON, N, ZETTERBERG, H, BIANCONI, S, YANJANIN, N. M, FU, R, MANSSON, J.-E, PORTER, F. D, BLENNOW, K

“…Niemann-Pick disease type C (NPC) is an inherited disorder characterized by intracellular accumulation of lipids such as cholesterol and glycosphingolipids in…”
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Mucopolysaccharidosis type III (Sanfilippo disease) in Sweden: clinical presentation of 22 children diagnosed during a 30-year period by Malm, G, Månsson, J-E

“…Aim:  The aim of this study was to present the natural clinical course in children and adolescents with MPS III diagnosed during a 30‐year period in Sweden…”
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The glycolipid sulfatide protects insulin-producing cells against cytokine-induced apoptosis, a possible role in diabetes by Roeske-Nielsen, A., Dalgaard, L. T., Månsson, J.-E., Buschard, K.

“…Aims/hypothesis Cytokine‐induced apoptosis is recognised as a major cause of the decline in β‐cell mass that ultimately leads to type 1 diabetes mellitus…”
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Administration of Sulfatide to Ameliorate Type I Diabetes in Non‐Obese Diabetic Mice by Rhost, S., Löfbom, L., Månsson, J.‐E., Lehuen, A., Blomqvist, M., Cardell, S. L.

“…The endogenous glycosphingolipid sulfatide is a ligand for CD1d‐restricted type II natural killer T (NKT) lymphocytes. Through the action of these cells,…”
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The earliest MR imaging and proton MR spectroscopy abnormalities in adult-onset Krabbe disease by Wang, C., Melberg, A., Weis, J., Månsson, J.-E., Raininko, R.

“…Background –  Adult‐onset Krabbe disease is an uncommon form of leukodystrophy. Its magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS)…”
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Ventricular cerebrospinal fluid neurofilament protein levels decrease in parallel with white matter pathology after shunt surgery in normal pressure hydrocephalus by Tullberg, M., Blennow, K., Månsson, J.-E., Fredman, P., Tisell, M., Wikkelsö, C.

“…Normal pressure hydrocephalus (NPH) is characterized by disturbed cerebrospinal fluid (CSF) dynamics and white matter lesions (WML). Although the morphology of…”
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Elevated cerebrospinal fluid levels of prostaglandin E2 and 15‐(S)‐hydroxyeicosatetraenoic acid in multiple sclerosis by Mattsson, N., Yaong, M., Rosengren, L., Blennow, K., Månsson, J.‐E., Andersen, O., Zetterberg, H., Haghighi, S., Zho, I., Pratico, D.

“… Objective.  To test the hypothesis that the arachodinic acid metabolites prostaglandin E2 (PGE2) and 15‐(S)‐hydroxyeicosatetraenoic acid (15(S)‐HETE) in…”
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White matter changes in normal pressure hydrocephalus and Binswanger disease: specificity, predictive value and correlations to axonal degeneration and demyelination by Tullberg, M., Hultin, L., Ekholm, S., Månsson, J.-E., Fredman, P., Wikkelsø, C.

“…Objectives– To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic…”
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Alpha-mannosidosis: characterization of CNS pathology and correlation between CNS pathology and cognitive function by Borgwardt, L., Danielsen, E.R., Thomsen, C., Månsson, J.E., Taouatas, N., Thuesen, A.M., Olsen, K.J., Fogh, J., Dali, C.I., Lund, A.M.

“…Alpha‐mannosidosis (AM) (OMIM 248500) is a rare lysosomal storage disease. The understanding of the central nervous system (CNS) pathology is limited. This…”
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The g.1170C>T polymorphism of the 5′ untranslated region of the human alpha-galactosidase gene is associated with decreased enzyme expression—Evidence from a family study by Oliveira, J. P., Ferreira, S., Reguenga, C., Carvalho, F., Månsson, J.-E.

“…Summary Subnormal leukocyte α-galactosidase (α-Gal) activity was found during evaluation of an adolescent male with cryptogenic cerebrovascular small-vessel…”
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Children born extremely preterm show significant lower cognitive, language and motor function levels compared with children born at term, as measured by the Bayley-III at 2.5 years by Månsson, J, Stjernqvist, K

“…Aim To assess developmental outcomes of children aged 2.5 years born extremely preterm. Methods As a part of the population‐based Extremely Preterm Infants in…”
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CSF sulfatide distinguishes between normal pressure hydrocephalus and subcortical arteriosclerotic encephalopathy by Tullberg, M, Månsson, J-E, Fredman, P, Lekman, A, Blennow, K, Ekman, R, Rosengren, L E, Tisell, M, Wikkelsø, C

“…OBJECTIVES To examine the CSF concentrations of molecules reflecting demyelination, neuronal and axonal degeneration, gliosis, monoaminergic neuronal function,…”
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Effect of single-nucleotide polymorphisms of the 5′ untranslated region of the human α-galactosidase gene on enzyme activity, and their frequencies in Portuguese caucasians by Oliveira, J. P., Ferreira, S., Barceló, J., Gaspar, P., Carvalho, F., Sá Miranda, M. C., Månsson, J.-E.

“…Summary Background: The α-galactosidase gene ( GLA ) has three single-nucleotide polymorphisms in the 5′ untranslated region of exon 1, respectively g.1150G>A,…”
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Bone marrow stem cell-based gene transfer in a mouse model for metachromatic leukodystrophy: effects on visceral and nervous system disease manifestations by MATZNER, U, HARTMANN, D, LÜLLMANN-RAUCH, R, COENEN, R, ROTHERT, F, MANSSON, J.-E, FREDMAN, P, D'HOOGE, R, DE DEYN, P. P, GIESELMANN, V

“…Arylsulfatase A (ASA) knockout mice represent an animal model for the lysosomal storage disease metachromatic leukodystrophy (MLD). Stem cell gene therapy with…”
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Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane by Lusa, S, Blom, T S, Eskelinen, E L, Kuismanen, E, Månsson, J E, Simons, K, Ikonen, E

“…In mammalian cells, cholesterol is thought to associate with sphingolipids to form lateral membrane domains termed rafts. Increasing evidence suggests that…”
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Growth hormone treatment affects brain neurotransmitters and thyroxine [see comment] by Burman, P, Hetta, J, Wide, L, Månsson, J E, Ekman, R, Karlsson, F A

“…Binding sites specific for growth hormone have been identified in the brain, but the action of GH on the central nervous system is still poorly understood. In…”
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Late cerebral graft versus host reaction in a bone marrow transplanted girl with Hurler (MPS I) disease by Kyllerman, M, Himmelmann, K, Fasth, A, Nordborg, C, Månsson, J-E

“…A girl with Hurler disease (MPS IH) underwent allogeneic stem cell transplantation at 13 months of age with her one HLA-B antigen mismatch mother as donor. The…”
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Non-neurological surgery results in a neurochemical stress response by Anckarsäter, R., Zetterberg, H., Månsson, J.-E., Blennow, K., Anckarsäter, H.

“…There is a paucity of studies assessing changes in measures of human neurotransmission during stressful events, such as surgery. Thirty-five patients without…”
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Differences in cerebrospinal fluid dynamics do not affect the levels of biochemical markers in ventricular CSF from patients with aqueductal stenosis and idiopathic normal pressure hydrocephalus by Tisell, M., Tullberg, M., Månsson, J.-E., Fredman, P., Blennow, K., Wikkelsø, C.

“…To compare levels of biochemical markers in ventricular cerebrospinal fluid (vCSF) between patients with aqueductal stenosis (AS) and idiopathic normal…”
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