Search Results - "Mänz, M."

Inequality indices to monitor geographic differences in incidence, mortality and fatality rates over time during the COVID-19 pandemic by Manz, Kirsi M, Mansmann, Ulrich

“…It is of interest to explore the variability in how the COVID-19 pandemic evolved geographically during the first twelve months. To this end, we apply…”
Get full text

Challenges in diagnosis and management of neutropenia upon exposure to immune-checkpoint inhibitors: meta-analysis of a rare immune-related adverse side effect by Boegeholz, J, Brueggen, C S, Pauli, C, Dimitriou, F, Haralambieva, E, Dummer, R, Manz, M G, Widmer, C C

“…Cancer immunotherapy via immune-checkpoint inhibition (ICI) by antibodies against cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and cell death protein 1…”
Get full text

Histamine H3 Receptor Function Biases Excitatory Gain in the Nucleus Accumbens by Manz, Kevin M., Becker, Jennifer C., Grueter, Carrie A., Grueter, Brad A.

“…Histamine (HA), a wake-promoting monoamine implicated in stress-related arousal states, is synthesized in histidine decarboxylase–expressing hypothalamic…”
Get full text

Impact of a Patient Blood Management monitoring and feedback programme on allogeneic blood transfusions and related costs by Kaserer, A., Rössler, J., Braun, J., Farokhzad, F., Pape, H.‐C., Dutkowski, P., Plass, A., Horisberger, T., Volbracht, J., Manz, M. G., Spahn, D. R.

“…Summary A Patient Blood Management programme was established at the University Hospital of Zurich, along with a monitoring and feedback programme, at the…”
Get full text

Longitudinal microbiome investigation throughout prion disease course reveals pre- and symptomatic compositional perturbations linked to short-chain fatty acid metabolism and cognitive impairment in mice by Losa, Marco, Morsy, Yasser, Emmenegger, Marc, Manz, Salomon M, Schwarz, Petra, Aguzzi, Adriano, Scharl, Michael

“…Commensal intestinal bacteria shape our microbiome and have decisive roles in preserving host metabolic and immune homeostasis. They conspicuously impact…”
Get full text

Calcium-Permeable AMPA Receptors Promote Endocannabinoid Signaling at Parvalbumin Interneuron Synapses in the Nucleus Accumbens Core by Manz, Kevin M., Ghose, Dipanwita, Turner, Brandon D., Taylor, Anne, Becker, Jennifer, Grueter, Carrie A., Grueter, Brad A.

“…Synaptic plasticity is a key mechanism of learning and memory. Synaptic plasticity mechanisms within the nucleus accumbens (NAc) mediate differential…”
Get full text

Lenalidomide added to standard intensive treatment for older patients with AML and high-risk MDS by Ossenkoppele, G. J., Breems, D. A., Stuessi, G., van Norden, Y., Bargetzi, M., Biemond, B. J., A von dem Borne, P., Chalandon, Y., Cloos, J., Deeren, D., Fehr, M., Gjertsen, B., Graux, C., Huls, G., Janssen, J. J. J. W., Jaspers, A., Jongen-Lavrencic, M., de Jongh, E., Klein, S. K., van der Klift, M., van Marwijk Kooy, M., Maertens, J., Michaux, L., van der Poel, M. W. M., van Rhenen, A., Tick, L., Valk, P., Vekemans, M. C., van der Velden, W. J. F. M., de Weerdt, O., Pabst, T., Manz, M., Löwenberg, B.

“…More effective treatment modalities are urgently needed in patients with acute myeloid leukemia (AML) of older age. We hypothesized that adding lenalidomide to…”
Get full text

Efficacy and side effects of immune checkpoint inhibitors in the treatment of colorectal cancer by Manz, Salomon M., Losa, Marco, Fritsch, Ralph, Scharl, Michael

“…Colorectal cancers (CRCs) remain one of the most common and challenging neoplasia in the Western world. The response rate of immunotherapeutic treatment…”
Get full text

SNAP25 differentially contributes to Gi/o-coupled receptor function at glutamatergic synapses in the nucleus accumbens by Manz, Kevin M., Zepeda, José C., Zurawski, Zack, Hamm, Heidi E., Grueter, Brad A.

“…The nucleus accumbens (NAc) guides reward-related motivated behavior implicated in pathological behavioral states, including addiction and depression. These…”
Get full text

Trichuris trichiura infection and its relation to environmental factors in Mbeya region, Tanzania: A cross-sectional, population-based study by Manz, Kirsi M, Clowes, Petra, Kroidl, Inge, Kowuor, Dickens O, Geldmacher, Christof, Ntinginya, Nyanda E, Maboko, Leonard, Hoelscher, Michael, Saathoff, Elmar

“…The intestinal nematode Trichuris trichiura is among the most common causes of human infectious disease worldwide. As for other soil-transmitted nematodes, its…”
Get full text

Comparative therapeutic value of post-remission approaches in patients with acute myeloid leukemia aged 40–60 years by Cornelissen, J J, Versluis, J, Passweg, J R, van Putten, W L J, Manz, M G, Maertens, J, Beverloo, H B, Valk, P J M, van Marwijk Kooy, M, Wijermans, P W, Schaafsma, M R, Biemond, B J, Vekemans, M-C, Breems, D A, Verdonck, L F, Fey, M F, Jongen-Lavrencic, M, Janssen, J J W M, Huls, G, Kuball, J, Pabst, T, Graux, C, Schouten, H C, Gratwohl, A, Vellenga, E, Ossenkoppele, G, Löwenberg, B

“…The preferred type of post-remission therapy (PRT) in patients with acute myeloid leukemia (AML) in first complete remission (CR1) is a subject of continued…”
Get full text

Relations of Serum Ascorbic Acid and α-tocopherol to Periodontal Disease by Iwasaki, M., Manz, M.C., Taylor, G.W., Yoshihara, A., Miyazaki, H.

“…Low concentrations of serum anti-oxidants, including ascorbic acid and α-tocopherol, are associated with higher risks of many inflammatory diseases that…”
Get full text

Schistosoma haematobium infection and environmental factors in Southwestern Tanzania: A cross-sectional, population-based study by Manz, Kirsi M., Kroidl, Inge, Clowes, Petra, Gerhardt, Martina, Nyembe, Wilbrod, Maganga, Lucas, Assisya, Weston, Ntinginya, Nyanda E., Berger, Ursula, Hoelscher, Michael, Saathoff, Elmar

“…Schistosomiasis is a leading cause of morbidity in Africa. Understanding the disease ecology and environmental factors that influence its distribution is…”
Get full text

Relationship between Saturated Fatty Acids and Periodontal Disease by Iwasaki, M., Manz, M.C., Moynihan, P., Yoshihara, A., Muramatsu, K., Watanabe, R., Miyazaki, H.

“…Saturated fatty acids (SFAs) produce an inflammatory response. Hyperinflammation is now recognized as one of the key underlying etiologic factors in…”
Get full text

Comparative value of post-remission treatment in cytogenetically normal AML subclassified by NPM1 and FLT3-ITD allelic ratio by Versluis, J, in ‘t Hout, F E M, Devillier, R, van Putten, W L J, Manz, M G, Vekemans, M -C, Legdeur, M -C, Passweg, J R, Maertens, J, Kuball, J, Biemond, B J, Valk, P J M, van der Reijden, B A, Meloni, G, Schouten, H C, Vellenga, E, Pabst, T, Willemze, R, Löwenberg, B, Ossenkoppele, G, Baron, F, Huls, G, Cornelissen, J J

“…Post-remission treatment (PRT) in patients with cytogenetically normal (CN) acute myeloid leukemia (AML) in first complete remission (CR1) is debated. We…”
Get full text

Correction: Lenalidomide added to standard intensive treatment for older patients with AML and high-risk MDS by Ossenkoppele, G. J., Breems, D. A., Stuessi, G., van Norden, Y., Bargetzi, M., Biemond, B. J., A von dem Borne, P., Chalandon, Y., Cloos, J., Deeren, D., Fehr, M., Gjertsen, B., Graux, C., Huls, G., Janssen, J. J. J. W., Jaspers, A., Jongen-Lavrencic, M., de Jongh, E., Klein, S. K., van der Klift, M., van Marwijk Kooy, M., Maertens, J., Michaux, L., van der Poel, M. W. M., van Rhenen, A., Tick, L., Valk, P., Vekemans, M. C., van der Velden, W. J. F. M., de Weerdt, O., Pabst, T., Manz, M., Löwenberg, B.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Patch-clamp and multi-electrode array electrophysiological analysis in acute mouse brain slices by Manz, Kevin M., Siemann, Justin K., McMahon, Douglas G., Grueter, Brad A.

“…Patch-clamp and multi-electrode array electrophysiology techniques are used to measure dynamic functional properties of neurons. Whole-cell and cell-attached…”
Get full text

Addition of the nuclear export inhibitor selinexor to standard intensive treatment for elderly patients with acute myeloid leukemia and high risk myelodysplastic syndrome by Janssen, J. J. W. M., Löwenberg, B., Manz, M., Biemond, B. J., Westerweel, P. E., Klein, S. K., Fehr, M., Sinnige, H. A. M., Efthymiou, A., Legdeur, M. C. J. C., Pabst, T., Gregor, M., van der Poel, M. W. M., Deeren, D., Tick, L. W., Jongen-Lavrencic, M., van Obbergh, F., Boersma, R. S., de Weerdt, O., Chalandon, Y., Heim, D., Spertini, O., van Sluis, G., Graux, C., Stüssi, G., van Norden, Y., Ossenkoppele, G. J.

“…Treatment results of AML in elderly patients are unsatisfactory. In an open label randomized phase II study, we investigated whether addition of the XPO1…”
Get full text

Distinct factors determine the kinetics of disease relapse in adults transplanted for acute myeloid leukaemia by Craddock, C., Versluis, J., Labopin, M., Socie, G., Huynh, A., Deconinck, E., Volin, L., Milpied, N., Bourhis, J. H., Rambaldi, A., Chevallier, P., Blaise, D., Manz, M., Vellenga, E., Vekemans, M‐C., Maertens, J., Passweg, J., Vyas, P., Schmid, C., Löwenberg, B., Ossenkoppele, G., Mohty, M., Cornelissen, J. J., Nagler, A.

“…Background Disease recurrence remains the major cause of death in adults with acute myeloid leukaemia (AML) treated using either intensive chemotherapy (IC) or…”
Get full text

Persistent organic pollutants in agricultural soils of central Germany by Manz, M, Wenzel, K.-D, Dietze, U, Schüürmann, G

“…Concentrations of persistent organic pollutants (HCHs, DDX, PCBs and HCB) were measured in topsoils from 11 agricultural fields in the lee of large disused…”
Get full text