Search Results - "Mäkinen, Elina"

Intrinsic running capacity associates with hippocampal electrophysiology and long-term potentiation in rats by Mäkinen, Elina E., Lensu, Sanna, Wikgren, Jan, Pekkala, Satu, Koch, Lauren G., Britton, Steven L., Nokia, Miriam S.

“…•Hippocampal long-term potentiation (LTP) is greater in high-fit than low-fit rats.•LTP correlates with the occurrence rate of dentate spikes and gamma…”
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Prebiotic Xylo-Oligosaccharides Ameliorate High-Fat-Diet-Induced Hepatic Steatosis in Rats by Lensu, Sanna, Pariyani, Raghunath, Mäkinen, Elina, Yang, Baoru, Saleem, Wisam, Munukka, Eveliina, Lehti, Maarit, Driuchina, Anastasiia, Lindén, Jere, Tiirola, Marja, Lahti, Leo, Pekkala, Satu

“…Understanding the importance of the gut microbiota (GM) in non-alcoholic fatty liver disease (NAFLD) has raised the hope for therapeutic microbes. We have…”
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Foods for Special Dietary Needs: Non-dairy Plant-based Milk Substitutes and Fermented Dairy-type Products by Mäkinen, Outi Elina, Wanhalinna, Viivi, Zannini, Emanuele, Arendt, Elke Karin

“…A growing number of consumers opt for plant-based milk substitutes for medical reasons or as a lifestyle choice. Medical reasons include lactose intolerance,…”
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Gastrointestinal Symptoms and Dopamine Transporter Asymmetry in Early Parkinson's Disease by Murtomäki, Kirsi, Mertsalmi, Tuomas, Jaakkola, Elina, Mäkinen, Elina, Levo, Reeta, Nojonen, Tanja, Eklund, Mikael, Nuuttila, Simo, Lindholm, Kari, Pekkonen, Eero, Joutsa, Juho, Noponen, Tommi, Ihalainen, Toni, Kaasinen, Valtteri, Scheperjans, Filip

“…Background The neurophysiological correlates of gastrointestinal symptoms (GISs) in Parkinson's disease (PD) are not well understood. It has been proposed that…”
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Diagnostic value of micrographia in Parkinson’s disease: a study with [123I]FP-CIT SPECT by Eklund, Mikael, Nuuttila, Simo, Joutsa, Juho, Jaakkola, Elina, Mäkinen, Elina, Honkanen, Emma A., Lindholm, Kari, Vahlberg, Tero, Noponen, Tommi, Ihalainen, Toni, Murtomäki, Kirsi, Nojonen, Tanja, Levo, Reeta, Mertsalmi, Tuomas, Scheperjans, Filip, Kaasinen, Valtteri

“…Micrographia is a common symptom of Parkinson’s disease (PD), and it may precede other motor symptoms. Despite the high prevalence of micrographia in PD, its…”
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Rats bred for low intrinsic aerobic exercise capacity link obesity with brain inflammation and reduced structural plasticity of the hippocampus by Mäkinen, Elina, Lensu, Sanna, Honkanen, Markus, Laitinen, Paavo, Wikgren, Jan, Koch, Lauren G., Britton, Steven L., Kainulainen, Heikki, Pekkala, Satu, Nokia, Miriam S.

“…[Display omitted] Increasing evidence shows obesity and poor metabolic health are associated with cognitive deficits, but the mechanistic connections have yet…”
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Visual versus automated analysis of [I-123]FP-CIT SPECT scans in parkinsonism by Mäkinen, Elina, Joutsa, Juho, Johansson, Jarkko, Mäki, Maija, Seppänen, Marko, Kaasinen, Valtteri

“…The clinical evaluation of dopamine transporter (DAT) SPECT scans typically relies on visual analysis in combination with an automated semi-quantitative…”
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Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease by Driuchina, Anastasiia, Hintikka, Jukka, Lehtonen, Marko, Keski-Rahkonen, Pekka, O'Connell, Thomas, Juvonen, Risto, Kuula, Juho, Hakkarainen, Antti, Laukkanen, Jari A, Mäkinen, Elina, Lensu, Sanna, Pietiläinen, Kirsi H, Pekkala, Satu

“…Numerous studies have described specific metabolites as biomarkers of severe liver diseases, but very few have measured gut microbiota (GM)-produced…”
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Dopamine transporter binding in the brain is linked to irritable bowel syndrome in Parkinson's disease by Murtomäki, Kirsi, Joutsa, Juho, Mertsalmi, Tuomas, Jaakkola, Elina, Mäkinen, Elina, Levo, Reeta, Eklund, Mikael, Nuuttila, Simo, Pekkonen, Eero, Noponen, Tommi, Ihalainen, Toni, Kaasinen, Valtteri, Scheperjans, Filip

“…Background Gastrointestinal symptoms are common in Parkinson's disease (PD), but their neurophysiological correlates are not well understood. We recently…”
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Diagnostic accuracy of glabellar tap sign for Parkinson’s disease by Nuuttila, Simo, Eklund, Mikael, Joutsa, Juho, Jaakkola, Elina, Mäkinen, Elina, Honkanen, Emma A., Lindholm, Kari, Noponen, Tommi, Ihalainen, Toni, Murtomäki, Kirsi, Nojonen, Tanja, Levo, Reeta, Mertsalmi, Tuomas, Scheperjans, Filip, Kaasinen, Valtteri

“…Glabellar tap or reflex (GR) is an old bedside clinical test used in the diagnostics of Parkinson’s disease (PD), but its diagnostic value is unclear. This…”
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Tuning Clinical Recruitment around Cultural Taboos in a Human Microbiome Study by Mäkinen, Elina I.

“…Human microbial communities are bodies of microorganisms that reside in or on different body parts. Importantly, they have been found to affect human health…”
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Burden of non-motor symptoms in unclear parkinsonism and tremor: A study with [123I]FP-CIT SPECT by Jaakkola, Elina, Joutsa, Juho, Mäkinen, Elina, Noponen, Tommi, Pitkonen, Miia, Levo, Reeta, Mertsalmi, Tuomas, Scheperjans, Filip, Kaasinen, Valtteri

“…Non-motor symptoms (NMSs) are clearly more prevalent in Parkinson's disease (PD) patients compared to healthy individuals. However, NMSs are also common in the…”
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Floating door sign does not differentiate Parkinson’s disease from essential tremor by Räty, Valtteri, Eklund, Mikael, Nuuttila, Simo, Jaakkola, Elina, Mäkinen, Elina, Murtomäki, Kirsi, Nojonen, Tanja, Levo, Reeta, Mertsalmi, Tuomas, Joutsa, Juho, Scheperjans, Filip, Kaasinen, Valtteri

“…Diagnostic usefulness of the floating door sign was tested in 144 PD patients, 41 essential tremor patients and 38 controls. There were no differences in the…”
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Fecal microbiome alterations in treatment-naive de novo Parkinson’s disease by Boertien, Jeffrey M., Murtomäki, Kirsi, Pereira, Pedro A. B., van der Zee, Sygrid, Mertsalmi, Tuomas H., Levo, Reeta, Nojonen, Tanja, Mäkinen, Elina, Jaakkola, Elina, Laine, Pia, Paulin, Lars, Pekkonen, Eero, Kaasinen, Valtteri, Auvinen, Petri, Scheperjans, Filip, van Laar, Teus

“…Gut microbiota alterations in Parkinson’s disease (PD) have been found in several studies and are suggested to contribute to the pathogenesis of PD. However,…”
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Dopamine transporter binding in symptomatic controls and healthy volunteers: Considerations for neuroimaging trials by Honkanen, Emma A., Eklund, Mikael, Nuuttila, Simo, Noponen, Tommi, Jaakkola, Elina, Mäkinen, Elina, Hirvilammi, Risto, Seppänen, Marko, Lindholm, Kari, Scheperjans, Filip, Parkkola, Riitta, Joutsa, Juho, Varrone, Andrea, Kaasinen, Valtteri

“…•Symptomatic controls have higher putaminal DAT binding than healthy controls.•The difference could be due to selection/self-selection bias or…”
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Risky Business: Meeting the Structural Needs of Transdisciplinary Science by Wise, Paul H., Shaw, Gary M., Druzin, Maurice L., Darmstadt, Gary L., Quaintance, Cecele, Mäkinen, Elina, Relman, David A., Quake, Stephen R., Butte, Atul J., Angst, Martin S., Muglia, Louis J., Macones, George, Driscoll, Deborah, Ober, Carole, Simpson, Joe Leigh, Katz, Michael, Howse, Jennifer, Stevenson, David K.

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Power and knowledge negotiations in a collectivity of practice: From peripheralization to epistemological suspicion by Mäkinen, Elina I

“…Knowledge co-creation at the boundaries of communities of practice (CoPs) can lead to heightened tensions and power struggles. This study examines how power…”
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Hedgehogs, foxes, and global science ecosystems: Decoding universities' research profiles across fields with nested ecological networks by Gomez, Charles J., Lieberman, Dahlia, Mäkinen, Elina I.

“…Modern scientific research evokes ecological imagery and metaphors, given that it is global, interdependent, and diverse. Ecological network structures—like…”
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The Power of Peer Review on Transdisciplinary Discovery by Mäkinen, Elina I.

“…This study examines the tension between the academic evaluation system and the development of unconventional research agendas. While scholars have studied the…”
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Making Sense of Science, University, and Industry: Sensemaking Narratives of Finnish and Israeli Scientists by Mäkinen, Elina I., Sapir, Adi

“…Academic entrepreneurship and the commercialization of science have transformed higher education in recent decades. Although there is ample research on the…”
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