Search Results - "Mário Antônio Spanó"
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Mutagenic, recombinogenic and carcinogenic potential of thiamethoxam insecticide and formulated product in somatic cells of Drosophila melanogaster
Published in Chemosphere (Oxford) (01-11-2017)“…Thiamethoxam (TMX) belongs to a class of neuro-active insecticides referred as neonicotinoids, while actara® (AC) is one of the most popular TMX-based products…”
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Assessment of the mutagenic, recombinogenic and carcinogenic potential of fipronil insecticide in somatic cells of Drosophila melanogaster
Published in Chemosphere (Oxford) (01-12-2016)“…Fipronil (FP) is an insecticide that belongs to the phenylpyrazole chemical family and is used to control pests by blocking GABA receptor at the entrance…”
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Assessment of mutagenic, recombinogenic and carcinogenic potential of titanium dioxide nanocristals in somatic cells of Drosophila melanogaster
Published in Food and chemical toxicology (01-02-2018)“…Nanoparticles have been widely used in several sectors and their long-term effect on the body and environment remains unknown. To evaluate the mutagenic,…”
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Mutagenicity and recombinogenicity evaluation of bupropion hydrochloride and trazodone hydrochloride in somatic cells of Drosophila melanogaster
Published in Food and chemical toxicology (01-09-2019)“…The aim of the present study was to appraise the mutagenic and recombinogenic potential of bupropion hydrochloride (BHc) and trazodone hydrochloride (THc). We…”
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Assessment of the carcinogenic potential of high intense-sweeteners through the test for detection of epithelial tumor clones (warts) in Drosophila melanogaster
Published in Food and chemical toxicology (01-03-2017)“…High intensity-sweeteners (HIS) are natural or synthetic substances, sweeter than sugar, providing sweetness without calories. Sweeteners are mainly used as an…”
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Modulatory effects of the antioxidant ascorbic acid on the direct genotoxicity of doxorubicin in somatic cells of Drosophila melanogaster
Published in Genetics and molecular biology (01-03-2007)“…In this study two different crosses involving the wing cell markers mwh and flr super(3)(standard (ST) cross and high bioactivation (HB) cross, the latter…”
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Evaluation of mutagenic, recombinogenic and carcinogenic potential of (+)-usnic acid in somatic cells of Drosophila melanogaster
Published in Food and chemical toxicology (01-10-2016)“…The main of this study was to evaluate the mutagenic and carcinogenic potential of (+) – usnic acid (UA), using Somatic Mutation and Recombination Test (SMART)…”
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Antigenotoxic effects of Mandevilla velutina (Gentianales, Apocynaceae) crude extract on cyclophosphamide-induced micronuclei in Swiss mice and urethane-induced somatic mutation and recombination in Drosophila melanogaster
Published in Genetics and molecular biology (2008)“…A Mandevilla velutina crude extract was investigated using the mouse micronucleus test (MNT) and the Drosophila melanogaster somatic mutation and recombination…”
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Comparative genotoxicity evaluation of imidazolinone herbicides in somatic cells of Drosophila melanogaster
Published in Food and chemical toxicology (2008)“…In the present study, five analogous herbicides, namely Imazapyr (IMZR), Imazapic (IMZC), Imazethapyr (IMZT), Imazamox (IMZX) and Imazaquin (IMZQ), were…”
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Genotoxicity of vesicular fluid and saline extract of Taenia solium metacestodes in somatic cells of Drosophila melanogaster
Published in Environmental and molecular mutagenesis (01-05-2006)“…Neurocysticercosis, the most common parasitic disease of the central nervous system, is caused by cysticerci of the helminth Taenia solium, which is prevalent…”
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Absence of genotoxicity of a phytotherapeutic extract from Stryphnodendron adstringens (Mart.) Coville in somatic and germ cells of Drosophila melanogaster
Published in Environmental and molecular mutagenesis (2003)“…Stryphnodendron adstringens (Mart.) Coville, a medicinal plant that grows in the “cerrados” (a savanna ecosystem) of Brazil, popularly known as “Barbatimão,”…”
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Protective effects of proanthocyanidins of grape ( Vitis vinifera L.) seeds on DNA damage induced by Doxorubicin in somatic cells of Drosophila melanogaster
Published in Food and chemical toxicology (01-07-2009)“…Proanthocyanidins (PAs), also known as condensed tannins, are naturally occurring oligomers and polymers of flavan-3-ol monomer units widely found in the…”
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A comparative study of the modulatory effects of (−)-cubebin on the mutagenicity/recombinogenicity induced by different chemical agents
Published in Food and chemical toxicology (01-05-2013)“…(1)…”
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Modulatory effects of metformin on mutagenicity and epithelial tumor incidence in doxorubicin-treated Drosophila melanogaster
Published in Food and chemical toxicology (01-08-2017)“…Metformin (MET) is an anti-diabetic drug used to prevent hepatic glucose release and increase tissue insulin sensitivity. Diabetic cancer patients are on…”
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Assessment of the genotoxic potential of two zinc oxide sources (amorphous and nanoparticles) using the in vitro micronucleus test and the in vivo wing somatic mutation and recombination test
Published in Food and chemical toxicology (01-10-2015)“…In this study, we evaluated the toxic and genotoxic potential of zinc oxide nanoparticles (ZnO NPs) of 20 nm and the mutagenic potential of these ZnO NPs as…”
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Avaliação do efeito modulador da levedura de cerveja (Saccharomyces cerevisiae M.) sobre a genotoxicidade induzida pela doxorrubicina em Drosophila melanogaster
Published in Revista de Biologia Neotropical (Online) (26-02-2014)“…O teste de mutação e recombinação somática (SMART) em Drosophila melanogaster foi utilizado para avaliar o potencial de genotoxicidade e antigenotoxicidade do…”
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Assessment of carcinogenic potential of soft drinks of cola, diet cola, orange and lemon, produced in the city of Uberlândia, Minas Gerais state, Brazil
Published in Bioscience journal (01-07-2016)“…Soft drinks are industrialized unfermented beverages, free of alcohol, carbonated, rich in artificial flavors and sugar. The intense consumption of such…”
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Modulatory effects of Tabebuia impetiginosa (Lamiales, Bignoniaceae) on doxorubicin-induced somatic mutation and recombination in Drosophila melanogaster
Published in Genetics and molecular biology (01-01-2009)“…The wing Somatic Mutation and Recombination Test (SMART) in D. melanogaster was used to study genotoxicity of the medicinal plant Tabebuia impetiginosa…”
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Mutagenic evaluation of combined paclitaxel and cisplatin treatment in somatic cells of Drosophila melanogaster
Published in Mutation research (02-02-2010)“…Recent studies have added paclitaxel (PAC) to traditional cisplatin (CIS) regimen to treat squamous cell carcinoma of the head and neck. The target of these…”
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Detection of micronuclei in peripheral erythrocytes of Cyprinus carpio exposed to metallic mercury
Published in Environmental and molecular mutagenesis (1997)“…Cyprinus carpio fish (carp), exposed to elemental or metallic mercury (Hg0) at concentrations of 2.0, 20.0, and 200.0 mg per liter of water, were kept in…”
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