Search Results - "MÖSSNER, R"

New insights into hidradenitis suppurativa: is lipocalin‐2 acting as an amplifier? by Mossner, R

“…Linked Article: Wolk et al. Br J Dermatol 2017; 177: 1385–1393…”
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A multicentre open‐label study of apremilast in palmoplantar pustulosis (APLANTUS) by Wilsmann‐Theis, D., Kromer, C., Gerdes, S., Linker, C., Magnolo, N., Sabat, R., Reich, K., Mössner, R.

“…Background Palmoplantar pustulosis (PPP) is a chronic skin disease with painful erythematous scaly or crusty lesions and pustules on the palms and soles…”
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The genetic basis for most patients with pustular skin disease remains elusive by Mössner, R., Wilsmann‐Theis, D., Oji, V., Gkogkolou, P., Löhr, S., Schulz, P., Körber, A., Prinz, J.C., Renner, R., Schäkel, K., Vogelsang, L., Peters, K.‐P., Philipp, S., Reich, K., Ständer, H., Jacobi, A., Weyergraf, A., Kingo, K., Kõks, S., Gerdes, S., Steinz, K., Schill, T., Griewank, K. G., Müller, M., Frey, S., Ebertsch, L., Uebe, S., Sticherling, M., Sticht, H., Hüffmeier, U.

“…Summary Background Rare variants in the genes IL36RN, CARD14 and AP1S3 have been identified to cause or contribute to pustular skin diseases, primarily…”
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Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017 by Hiemke, C, Bergemann, N, Clement, H W, Conca, A, Deckert, J, Domschke, K, Eckermann, G, Egberts, K, Gerlach, M, Greiner, C, Gründer, G, Haen, E, Havemann-Reinecke, U, Hefner, G, Helmer, R, Janssen, G, Jaquenoud, E, Laux, G, Messer, T, Mössner, R, Müller, M J, Paulzen, M, Pfuhlmann, B, Riederer, P, Saria, A, Schoppek, B, Schoretsanitis, G, Schwarz, M, Gracia, M Silva, Stegmann, B, Steimer, W, Stingl, J C, Uhr, M, Ulrich, S, Unterecker, S, Waschgler, R, Zernig, G, Zurek, G, Baumann, P

“…Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug concentrations in blood to optimize pharmacotherapy. It considers the…”
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Epidemiology and clinical pattern of psoriatic arthritis in Germany: a prospective interdisciplinary epidemiological study of 1511 patients with plaque-type psoriasis by Reich, K., Krüger, K., Mössner, R., Augustin, M.

“…Summary Background  Because psoriatic arthritis (PsA) usually develops years after the first manifestation of skin symptoms, in many cases the initial…”
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Changing within the same class: efficacy of brodalumab in plaque psoriasis after treatment with an IL-17A blocker - a retrospective multicenter study by Kromer, C, Wilsmann-Theis, D, Gerdes, S, Krebs, S, Pinter, A, Philipp, S, Mössner, R

“…Biologic switching is common in psoriasis patients with non-response to or adverse events under therapy with a biologic. However, evidence on efficacy of…”
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Successful therapy with anakinra in a patient with generalized pustular psoriasis carrying IL36RN mutations by Hüffmeier, U., Wätzold, M., Mohr, J., Schön, M.P., Mössner, R.

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Erythema nodosum-like lesions during BRAF inhibitor therapy: Report on 16 new cases and review of the literature by Mössner, R., Zimmer, L., Berking, C., Hoeller, C., Loquai, C., Richtig, E., Kähler, K.C., Hassel, J.C., Gutzmer, R., Ugurel, S.

“…Importance BRAF inhibitors have been licensed for the therapy of BRAF‐mutated melanoma. Recently, inflammatory skin lesions clinically resembling erythema…”
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Early endothelial progenitor cells and vascular stiffness in psoriasis and psoriatic arthritis by Patschan, D, Sugiarto, N, Henze, E, Mößner, R, Mohr, J, Müller, G A, Patschan, S

“…Both psoriasis (Ps) and psoriasis arthritis (PsA) have been associated with increased cardiovascular risk. Also, both are characterized by increased…”
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Venlafaxine’s therapeutic reference range in the treatment of depression revised: a systematic review and meta-analysis by Lense, X.M., Hiemke, C., Funk, C.S.M., Havemann-Reinecke, U., Hefner, G., Menke, A., Mössner, R., Riemer, T.G., Scherf-Clavel, M., Schoretsanitis, G., Gründer, G., Hart, X.M.

“…Introduction The selective serotonin and norepinephrine reuptake inhibitor venlafaxine is among the most prescribed antidepressant drugs worldwide and,…”
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The challenge of palmoplantar pustulosis therapy: Are Interleukin‐23 inhibitors an option? by Poortinga, S., Balakirski, G., Kromer, C., Mössner, R., Schön, M.P., Bieber, T., Wilsmann‐Theis, D.

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A functional serotonin transporter gene polymorphism is associated with migraine with aura by MARZINIAK, M, MÖSSNER, R, SCHMITT, A, LESCH, K. P, SOMMER, C

“…An association study was performed in 197 migraineurs with regard to a functional serotonin (5-HT) transporter (5-HTT) gene promoter polymorphism that leads to…”
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Allelic variation in 5-HT1A receptor expression is associated with anxiety- and depression-related personality traits by STROBEL, A, GUTKNECHT, L, ROTHE, C, REIF, A, MÖSSNER, R, ZENG, Y, BROCKE, B, LESCH, K.-P

“…The 5-HT1A receptor plays a critical role in the pathophysiology of anxiety and depression as well as in the mode of action of anxiolytic and antidepressant…”
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Lack of the serotonin transporter in mice reduces locomotor activity and leads to gender-dependent late onset obesity by Üçeyler, N, Schutt, M, Palm, F, Vogel, C, Meier, M, Schmitt, A, Lesch, K.P, Mossner, R, Sommer, C

“…Objective: Mice deficient of the serotonin transporter (5-HTT ko) mice have a reduced brain serotonin content and develop late-onset obesity. To elucidate the…”
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Long-term follow-up of 22 psoriatic patients treated with ixekizumab after failure of secukinumab by Amschler, K, Phillip, S, Mohr, J, Wilsmann-Theis, D, Poortinga, S, Gerdes, S, Mössner, R

“…Switching of biologic agents in treatment of plaque psoriasis is a common strategy. Only a few studies are available on switching between IL17A-blockers. In a…”
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Long-term follow-up of 22 psoriatic patients treated with ixekizumab after failure of secukinumab by Amschler, K, Phillip, S, Mohr, J, Wilsmann-Theis, D, Poortinga, S, Gerdes, S, Mössner, R

“…The original article was published on February 15, 2020 and corrected on March 26, 2020. The revised version of the article amends the table and figure, while…”
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Glucocorticoid‐regulated human serotonin transporter (5‐HTT) expression is modulated by the 5‐HTT gene‐promotor‐linked polymorphic region by Glatz, K., Mössner, R., Heils, A., Lesch, K. P.

“…Mood, emotion and cognition are modulated by serotonergic neurotransmission, while the physiological function of serotonergic synapses depends on serotonin…”
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A multicenter DeCOG study on predictors of vemurafenib therapy outcome in melanoma: pretreatment impacts survival by Ugurel, S., Loquai, C., Kähler, K., Hassel, J., Berking, C., Zimmer, L., Haubitz, I., Satzger, I., Müller-Brenne, T., Mikhaimer, N.C., Becker, J.C., Kilian, K.J., Schadendorf, D., Heinzerling, L., Kaatz, M., Utikal, J., Göppner, D., Pföhler, C., Pflugfelder, A., Mössner, R., Gutzmer, R.

“…This multicenter retrospective study investigated clinical characteristics as predictors of the outcome of treatment with the BRAF inhibitor vemurafenib in…”
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αCaMKII controls the establishment of cocaine's reinforcing effects in mice and humans by Easton, A C, Lourdusamy, A, Havranek, M, Mizuno, K, Solati, J, Golub, Y, Clarke, T-K, Vallada, H, Laranjeira, R, Desrivières, S, Moll, G H, Mössner, R, Kornhuber, J, Schumann, G, Giese, K P, Fernandes, C, Quednow, B B, Müller, C P

“…Although addiction develops in a considerable number of regular cocaine users, molecular risk factors for cocaine dependence are still unknown. It was proposed…”
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Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders? by Lesch, Klaus-Peter, Mössner, Rainald

“…Serotonin (5-HT) is an important regulator of morphogenetic activities during early central nervous system development, including cell proliferation,…”
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