Search Results - "MÖLLER, Lennart"

Size-dependent toxicity of metal oxide particles—A comparison between nano- and micrometer size by Karlsson, Hanna L., Gustafsson, Johanna, Cronholm, Pontus, Möller, Lennart

“…Toxicological studies have shown increased toxicity of nanoparticles (<100 nm) compared to micrometer particles of the same composition, which has raised…”
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Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes by Karlsson, Hanna L, Cronholm, Pontus, Gustafsson, Johanna, Möller, Lennart

“…Since the manufacture and use of nanoparticles are increasing, humans are more likely to be exposed occupationally or via consumer products and the…”
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Time trends in survival and causes of death in multiple myeloma: a population-based study from Germany by Eisfeld, Christine, Kajüter, Hiltraud, Möller, Lennart, Wellmann, Ina, Shumilov, Evgenii, Stang, Andreas

“…Steady evolution of therapies has improved prognosis of patients with multiple myeloma (MM) over the past two decades. Yet, knowledge about survival trends and…”
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Surface Characteristics, Copper Release, and Toxicity of Nano- and Micrometer-Sized Copper and Copper(II) Oxide Particles: A Cross-Disciplinary Study by Midander, Klara, Cronholm, Pontus, Karlsson, Hanna L., Elihn, Karine, Möller, Lennart, Leygraf, Christofer, Wallinder, Inger Odnevall

“…An interdisciplinary and multianalytical research effort is undertaken to assess the toxic aspects of thoroughly characterized nano‐ and micrometer‐sized…”
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The effects on DNA migration of altering parameters in the comet assay protocol such as agarose density, electrophoresis conditions and durations of the enzyme or the alkaline treatments by Ersson, Clara, Möller, Lennart

“…The single cell gel electrophoresis (comet assay) is a popular method for measuring DNA migration as an estimate of DNA damage. No standardised comet assay…”
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Copper-based nanoparticles induce high toxicity in leukemic HL60 cells by Rodhe, Ylva, Skoglund, Sara, Odnevall Wallinder, Inger, Potácová, Zuzana, Möller, Lennart

“…•High cytotoxicity of copper-based nanoparticles in HL60 cells.•Cu NPs were the most cytotoxic particles followed by CuCl2 and CuO NPs.•Cu NPs were less stable…”
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Mortality from prostate cancer in the years 2007-2021 in North Rhine-Westphalia, Germany by Claaßen, Kevin, Karpinski, Madeleine, Kajüter, Hiltraud, Hüsing, Johannes, Möller, Lennart, Wellmann, Ina, Grünwald, Viktor, Hadaschik, Boris, Albers, Peter, Stang, Andreas

“…The crude mortality rate and the lifetime mortality risk from prostate cancer in Germany are above international average. However age-standardised mortality…”
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Subway Particles Are More Genotoxic than Street Particles and Induce Oxidative Stress in Cultured Human Lung Cells by Karlsson, Hanna L, Nilsson, Lennart, Möller, Lennart

“…Epidemiological studies have shown an association between airborne particles and a wide range of adverse health effects. The mechanisms behind these effects…”
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Bioaccessibility, bioavailability and toxicity of commercially relevant iron- and chromium-based particles: in vitro studies with an inhalation perspective by Hedberg, Yolanda, Gustafsson, Johanna, Karlsson, Hanna L, Möller, Lennart, Odnevall Wallinder, Inger

“…Production of ferrochromium alloys (FeCr), master alloys for stainless steel manufacture, involves casting and crushing processes where particles inevitably…”
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Mechanisms Related to the Genotoxicity of Particles in the Subway and from Other Sources by Karlsson, Hanna L, Holgersson, Åsa, Möller, Lennart

“…Negative health effects of airborne particles have clearly been shown in epidemiological studies. People get exposed to particles from various sources such as…”
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Comparison of genotoxic and inflammatory effects of particles generated by wood combustion, a road simulator and collected from street and subway by Karlsson, Hanna L., Ljungman, Anders G., Lindbom, John, Möller, Lennart

“…The health effects of exposure to airborne particles are of increasing concern in society. In order to protect public health, a clarification of the toxic…”
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Assessment and reduction of comet assay variation in relation to DNA damage: studies from the European Comet Assay Validation Group by Møller, Peter, Möller, Lennart, Godschalk, Roger W. L., Jones, George D. D.

“…The alkaline single cell gel electrophoresis (comet) assay has become a widely used method for the detection of DNA damage and repair in cells and tissues…”
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DNA adduct and tumor formations in rats after intratracheal administration of the urban air pollutant 3-nitrobenzanthrone by Nagy, Eszter, Zeisig, Magnus, Kawamura, Ken, Hisamatsu, Yoshiharu, Sugeta, Akiko, Adachi, Shuichi, Möller, Lennart

“…3-Nitrobenzanthrone (3-NBA) has been isolated from diesel exhaust and airborne particles and identified as a potent direct-acting mutagen in vitro and…”
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DNA oxidative damage and strand breaks in young healthy individuals: a gender difference and the role of life style factors by Hofer, Tim, Karlsson, Hanna L, Möller, Lennart

“…The aim of this study was to analyze background levels of DNA damage in young (19-31 years) non-smoking individuals and to correlate damage to gender and life…”
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Effect of sonication and serum proteins on copper release from copper nanoparticles and the toxicity towards lung epithelial cells by Cronholm, Pontus, Midander, Klara, Karlsson, Hanna L., Elihn, Karine, Wallinder, Inger Odnevall, Möller, Lennart

“…Abstract Different methodological settings can influence particle characteristics and toxicity in nanotoxicology. The aim of this study was to investigate how…”
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Cellular dose of partly soluble Cu particle aerosols at the air-liquid interface using an in vitro lung cell exposure system by Elihn, Karine, Cronholm, Pontus, Karlsson, Hanna L, Midander, Klara, Odnevall Wallinder, Inger, Möller, Lennart

“…There is currently a need to develop and test in vitro systems for predicting the toxicity of nanoparticles. One challenge is to determine the actual cellular…”
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Vitamins at physiological levels cause oxidation to the DNA nucleoside deoxyguanosine and to DNA—alone or in synergism with metals by BERGSTROM, Therese, ERSSON, Clara, BERGMAN, Jan, MÖLLER, Lennart

“…Vitamins with antioxidant properties have the ability to act as pro-oxidants, inducing oxidative damage and oxidative stress as opposed to preventing it. While…”
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Vitamin A and C compounds permitted in supplements differ in their abilities to affect cell viability, DNA and the DNA nucleoside deoxyguanosine by Bergström, Therese, Bergman, Jan, Möller, Lennart

“…In accordance with the European Parliament and Council's directive, vitamin A and C supplements can include any of four (vitamin A) or five (vitamin C)…”
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Glycaemic status in relation to oxidative stress and inflammation in well-controlled type 2 diabetes subjects by Rytter, Elisabet, Vessby, Bengt, Åsgård, Rikard, Johansson, Clara, Sjödin, Anders, Abramsson-Zetterberg, Lilianne, Möller, Lennart, Basu, Samar

“…The aim of the present observational study was to investigate the relationships between glycaemic status and levels of oxidative stress and inflammation in…”
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The Effect of Sea Buckthorn Supplement on Oral Health, Inflammation, and DNA Damage in Hemodialysis Patients: A Double-Blinded, Randomized Crossover Study by Rodhe, Ylva, MSc, Lic Med Sci, Woodhill, Therese, MSc, Thorman, Royne, DDS, PhD, Möller, Lennart, PhD, Hylander, Britta, MD, PhD

“…Objective Chronic kidney disease is associated with inflammation, oxidative stress, malnutrition, poor oral health, and mouth dryness. The objective of this…”
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