Search Results - "Lyzogubov, V. V."

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy by Obrosova, Irina G., Xu, Weizheng, Lyzogubov, Valeriy V., Ilnytska, Olga, Mashtalir, Nazar, Vareniuk, Igor, Pavlov, Ivan A., Zhang, Jie, Slusher, Barbara, Drel, Viktor R.

“…Evidence that poly(ADP-ribose) polymerase (PARP) activation plays an important role in diabetic complications is emerging. This study evaluated the role of…”
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PHF19 inhibition as a therapeutic target in multiple myeloma by Schinke, Carolina D., Bird, Jordan T., Qu, Pingping, Yaccoby, Shmuel, Lyzogubov, Valeriy V., Shelton, Randal, Ling, Wen, Boyle, Eileen M., Deshpande, Sharyu, Byrum, Stephanie D., Washam, Charity, Mackintosh, Samuel, Stephens, Owen, Thanendrarajan, Sharmilan, Zangari, Maurizio, Shaughnessy, John, Zhan, Fenghuang, Barlogie, Bart, van Rhee, Frits, Walker, Brian A

“…Epigenetic deregulation is increasingly recognized as a contributing pathological factor in multiple myeloma (MM). In particular tri-methylation of H3 lysine…”
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A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice by Drel, Viktor R., Pacher, Pal, Vareniuk, Igor, Pavlov, Ivan, Ilnytska, Olga, Lyzogubov, Valeriy V., Tibrewala, Jyoti, Groves, John T., Obrosova, Irina G.

“…Whereas an important role of free radicals and oxidants in peripheral diabetic neuropathy is well established, the contribution of nitrosative stress and, in…”
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Poly(ADP-Ribose) Polymerase Inhibition Alleviates Experimental Diabetic Sensory Neuropathy by ILNYTSKA, Olga, LYZOGUBOV, Valeriy V, STEVENS, Martin J, DREL, Viktor R, MASHTALIR, Nazar, PACHER, Pal, YOREK, Mark A, OBROSOVA, Irina G

“…Poly(ADP-Ribose) Polymerase Inhibition Alleviates Experimental Diabetic Sensory Neuropathy Olga Ilnytska 1 , Valeriy V. Lyzogubov 1 , Martin J. Stevens 2 ,…”
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Relationship between Complement Membrane Attack Complex, Chemokine (C-C Motif) Ligand 2 (CCL2) and Vascular Endothelial Growth Factor in Mouse Model of Laser-induced Choroidal Neovascularization by Liu, Juan, Jha, Purushottam, Lyzogubov, Valeriy V., Tytarenko, Ruslana G., Bora, Nalini S., Bora, Puran S.

“…The present study investigated the interactions among the complement membrane attack complex (MAC), CCL2, and VEGF that occur in vivo during the development of…”
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Expression of adiponectin in choroidal tissue and inhibition of laser induced choroidal neovascularization by adiponectin by Bora, Puran S., Kaliappan, Sankaranarayanan, Lyzogubov, Valeriy V., Tytarenko, Ruslana G., Thotakura, Sushma, Viswanathan, Tito, Bora, Nalini S.

“…The aim of this study was to investigate the role of adiponectin (APN) in a mouse model of laser induced choroidal neovascularization (CNV). We have shown by…”
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Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient ( ob/ob) mice by Vareniuk, Igor, Pavlov, Ivan A., Drel, Viktor R., Lyzogubov, Valeriy V., Ilnytska, Olga, Bell, Seth R., Tibrewala, Jyoti, Groves, John T., Obrosova, Irina G.

“…Nitrosative stress contributes to nerve conduction slowing, thermal hypoalgesia, and impaired nitrergic innervation in animal models of Type 1 diabetes. The…”
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Immunohistochemical analysis of NaPi2b protein (MX35 antigen) expression and subcellular localization in human normal and cancer tissues by Kiyamova, R, Shyian, M, Lyzogubov, V V, Usenko, V S, Gout, T, Filonenko, V

“…To study the expression profile of the NaPi2b protein and its localization in breast, ovarian and lung cancer cells in relation to normal tissues adjacent to…”
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Relationship between the complement system, risk factors and prediction models in age-related macular degeneration by Bora, Nalini S., Matta, Bharati, Lyzogubov, Valeriy V., Bora, Puran S.

“…•Association of complement system with AMD risk factors and AMD prediction models.•This information would improve our understanding of AMD pathology.•Could…”
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The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration–Like Phenotype by Lyzogubov, Valeriy V, Bora, Puran S, Wu, Xiaobo, Horn, Leah E, de Roque, Ryan, Rudolf, Xeniya V, Atkinson, John P, Bora, Nalini S

“…In the mouse, membrane cofactor protein (CD46), a key regulator of the alternative pathway of the complement system, is only expressed in the eye and on the…”
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High-fat diet-induced neuropathy of pre-diabetes and obesity : Effects of healthy diet and aldose reductase inhibition by OBROSOVA, Irina G, ILNYTSKA, Olga, LYZOGUBOV, Valeriy V, PAVLOV, Ivan A, MASHTALIR, Nazar, NADLER, Jerry L, DREL, Viktor R

“…Subjects with dietary obesity and pre-diabetes have an increased risk for developing both nerve conduction slowing and small sensory fiber neuropathy. Animal…”
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The leptin-deficient (ob/ob) mouse : A new animal model of peripheral neuropathy of type 2 diabetes and obesity by DREL, Viktor R, MASHTALIR, Nazar, ILNYTSKA, Olga, SHIN, Jeho, FEI LI, LYZOGUBOV, Valeriy V, OBROSOVA, Irina G

“…Whereas functional, metabolic, neurotrophic, and morphological abnormalities of peripheral diabetic neuropathy (PDN) have been extensively explored in…”
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Polyethylene Glycol (PEG)-induced Mouse Model of Choroidal Neovascularization by Lyzogubov, Valeriy V., Tytarenko, Ruslana G., Liu, Juan, Bora, Nalini S., Bora, Puran S.

“…In this study, we describe a new method for inducing choroidal neovascularization (CNV) in C57BL/6 mice, an animal model of wet age-related macular…”
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Polyethylene glycol induced mouse model of retinal degeneration by Lyzogubov, Valeriy V., Bora, Nalini S., Tytarenko, Ruslana G., Bora, Puran S.

“…Age-related macular degeneration (AMD) is a leading cause of irreversible blindness. This study was done to characterize dry AMD-like changes in mouse retinal…”
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Role of Ocular Complement Factor H in a Murine Model of Choroidal Neovascularization by Lyzogubov, Valeriy V, Tytarenko, Ruslana G, Jha, Purushottam, Liu, Juan, Bora, Nalini S, Bora, Puran S

“…The objective of this study was to explore the relationship between local (ie, ocular) complement factor H (CFH) and choroidal neovascularization (CNV)…”
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Involvement of human beta-defensin-2 in proliferation of transformed cells of human cervix by Markeeva, N, Lysovskiy, I, Zhuravel, E, Soldatkina, M, Lyzogubov, V, Usenko, V, Potapov, V, Pogrebnoy, P

“…To evaluate the influence of human beta-defensin-2 (hBD-2) on viability and proliferation of cultured human epithelial cells and the patterns of hBD-2…”
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Inhibitory role of adiponectin peptide I on rat choroidal neovascularization by Lyzogubov, Valeriy V., Tytarenko, Ruslana G., Bora, Nalini S., Bora, Puran S.

“…Age-related macular degeneration (AMD) is a leading cause of central blindness in the elderly population. The wet type of AMD is characterized by extensive…”
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Recombinant Membrane-targeted Form of CD59 Inhibits the Growth of Choroidal Neovascular Complex in Mice by Bora, Nalini S., Jha, Purushottam, Lyzogubov, Valeriy V., Kaliappan, Sankaranarayanan, Liu, Juan, Tytarenko, Ruslana G., Fraser, Deborah A., Morgan, B. Paul, Bora, Puran S.

“…This study was designed to explore the effect of recombinant, membrane-targeted CD59 (rCD59-APT542) on the growth and size of fully developed neovascular…”
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Effect of aspirin on models of retinal pigment epithelium pathology by Goyal, Sunali, Lyzogubov, Valeriy V, Ali, Omair, Bora, Puran S, Bora, Nalini S, Uwaydat, Sami H

“…Background To characterize the effect of aspirin (ASA) in mouse models of choroidal neovascularization (CNV) and retinal degeneration. Methods In vivo: Male…”
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The effect of nicotine on anti-vascular endothelial growth factor therapy in a mouse model of neovascular age-related macular degeneration by Davis, Stephen J, Lyzogubov, Valeriy V, Tytarenko, Ruslana G, Safar, Ammar N, Bora, Nalini S, Bora, Puran S

“…The purpose of this article is to evaluate the effect of nicotine on anti-vascular endothelial growth factor therapy in the treatment of neovascular…”
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