Search Results - "Lyu, Zhengbing"
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Shark IgNAR: The Next Broad Application Antibody in Clinical Diagnoses and Tumor Therapies?
Published in Marine drugs (01-09-2023)“…Antibodies represent a relatively mature detection means and serve as therapeutic drug carriers in the clinical diagnosis and treatment of cancer—among which…”
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Advantages of the zebrafish tumor xenograft model: the evaluation of efficacy in cancer therapy and the application to the study of lncRNAs
Published in Frontiers in immunology (30-09-2024)“…In the current preclinical anti-tumor researches, there is a general lack of an model that can quickly and efficiently screen effective anti-tumor drugs. As a…”
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5-Hydroxymethylcytosine: Far Beyond the Intermediate of DNA Demethylation
Published in International journal of molecular sciences (02-11-2024)“…Epigenetics plays a pivotal role in regulating gene expression and cellular differentiation. DNA methylation, involving the addition of methyl groups to…”
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Screening and anti-angiogenesis activity of Chiloscyllium plagiosum anti-human VEGFR2 single-domain antibody
Published in Clinical and experimental immunology (16-10-2024)“…Recently, the incidence of malignant tumors is on the rise and searching for new treatments on it has become the research priority. Blocking the vascular…”
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Screening and anti‐glioma activity of Chiloscyllium plagiosum anti‐human IL‐13Rα2 single‐domain antibody
Published in Immunology (01-09-2023)“…Glioblastoma is a common and fatal malignant tumour of the central nervous system, with high invasiveness. Conventional treatments for this disease, including…”
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IgNAR characterization and gene loci identification in whitespotted bamboo shark (Chiloscyllium plagiosum) genome
Published in Fish & shellfish immunology (01-02-2023)“…Single domain antibodies (sdAb) are promising candidates in cancer and anti-virus biotherapies for their unique structure characters. Though VHH and IgNAR have…”
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Antigen specific VNAR screening in whitespotted bamboo shark (Chiloscyllium plagiosum) with next generation sequencing
Published in Fish & shellfish immunology (01-07-2024)“…IgNAR exhibits significant promise in the fields of cancer and anti-virus biotherapies. Notably, the variable regions of IgNAR (VNAR) possess comparable…”
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Expression, Purification, and Anti-UV Irradiation Effect of RsSOD on HCE-T Human Corneal Epithelial Cells
Published in Genes (30-08-2024)“…Superoxide dismutase (SOD) is a class of enzymes that catalyze the disproportionation of superoxide anion radicals into hydrogen peroxide and oxygen. It can…”
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Ulp1 Regulates Cell Proliferation Through INO1 in Pichia pastoris
Published in Genes (13-11-2024)“…Background/Objectives: Ulp1 is a vital regulator of the cell cycle, with its absence leading to G2/M phase arrest in Saccharomyces cerevisiae. This study aims…”
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