Search Results - "Lyu, Guoliang"
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TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging
Published in Nature communications (02-07-2018)“…Cellular senescence is a well-orchestrated programmed process involved in age-related pathologies, tumor suppression and embryonic development. TGF-β/Smad is…”
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2
Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts
Published in Nucleic acids research (04-11-2020)“…Abstract The three-dimensional configuration of the chromatin architecture is known to be crucial for alterations in the transcriptional network; however, the…”
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3
Gene body methylation safeguards ribosomal DNA transcription by preventing PHF6-mediated enrichment of repressive histone mark H4K20me3
Published in The Journal of biological chemistry (01-10-2021)“…DNA methylation shows complex correlations with gene expression, and the role of promoter hypermethylation in repressing gene transcription has been well…”
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4
Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease
Published in BMC genomics (04-06-2018)“…Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants…”
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The chromatin remodeling factor CSB recruits histone acetyltransferase PCAF to rRNA gene promoters in active state for transcription initiation
Published in PloS one (07-05-2013)“…The promoters of poised rRNA genes (rDNA) are marked by both euchromatic and heterochromatic histone modifications and are associated with two transcription…”
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6
Addendum: TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging
Published in Nature communications (08-10-2018)Get full text
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7
On an approach to boosting a journal’s citation potential
Published in Scientometrics (15-09-2019)“…This study explored an approach to boosting a journal’s citation potential by proposing the Referenced Value of a journal (RFV j ) as a new measure for…”
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3' UTR lengthening as a novel mechanism in regulating cellular senescence
Published in Genome research (01-03-2018)“…Cellular senescence has been viewed as a tumor suppression mechanism and also as a contributor to individual aging. Widespread shortening of 3' untranslated…”
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Long Non-coding RNA ZFPM2-AS1: A Novel Biomarker in the Pathogenesis of Human Cancers
Published in Molecular biotechnology (01-07-2022)“…Due to their biological activities in regulating dosage compensation, epigenetics, and cell differentiation, long non-coding RNAs (lncRNA) have been recognized…”
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10
NuRD Blocks Reprogramming of Mouse Somatic Cells into Pluripotent Stem Cells
Published in Stem cells (Dayton, Ohio) (01-07-2013)“…Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by overexpression of a defined set of transcription factors requires epigenetic…”
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Changes in the position and volume of inactive X chromosomes during the G0/G1 transition
Published in Chromosome research (01-09-2018)“…In female mammals, each cell silences one X chromosome by converting it into transcriptionally inert heterochromatin. The inactivation is concomitant with…”
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Corrigendum: 3′ UTR lengthening as a novel mechanism in regulating cellular senescence
Published in Genome research (01-09-2020)Get full text
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13
Metastasis-related methyltransferase 1 (Merm1) represses the methyltransferase activity of Dnmt3a and facilitates RNA polymerase I transcriptional elongation
Published in Journal of molecular cell biology (01-01-2019)“…Stimulatory regulators for DNA methyltransferase activity, such as Dnmt3L and some Dnmt3b isoforms, affect DNA methylation patterns, thereby maintaining gene…”
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14
Addendum: TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging
Published in Nature communications (08-10-2018)Get full text
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15
The Chromatin Remodeling Factor CSB Recruits Histone Acetyltransferase PCAF to rRNA Gene Promoters in Active State for Transcription Initiation. e62668
Published in PloS one (01-05-2013)“…The promoters of poised rRNA genes (rDNA) are marked by both euchromatic and heterochromatic histone modifications and are associated with two transcription…”
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