Search Results - "Lytle, Kelli A."

Omega-3 polyunsaturated fatty acids as a treatment strategy for nonalcoholic fatty liver disease by Jump, Donald B, Lytle, Kelli A, Depner, Christopher M, Tripathy, Sasmita

“…Obese and type 2 diabetic (T2DM) patients have a high prevalence of nonalcoholic fatty liver disease (NAFLD). NAFLD is a continuum of chronic liver diseases…”
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Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible? by Lytle, Kelli A, Jump, Donald B

“…Nonalcoholic fatty liver disease (NAFLD) is a major public health burden in western societies. The progressive form of NAFLD, nonalcoholic steatohepatitis…”
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Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice by Lytle, Kelli A, Wong, Carmen P, Jump, Donald B

“…Nonalcoholic fatty liver disease (NAFLD) is a major public health concern in western societies. Nonalcoholic steatohepatitis (NASH), the progressive form of…”
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Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr−/− mice by targeting the TGFβ-Smad3 pathway by Lytle, Kelli A., Depner, Christopher M., Wong, Carmen P., Jump, Donald B.

“…DHA (22:6,ω3), but not EPA (20:5,ω3), attenuates Western diet (WD)-induced hepatic fibrosis in a Ldlr−/− mouse model of nonalcoholic steatohepatitis. We…”
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Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr−/− mice by Jump, Donald B., Depner, Christopher M., Tripathy, Sasmita, Lytle, Kelli A.

“…The prevalence of non-alcoholic fatty liver disease (NAFLD) has increased in parallel with central obesity and is now the most common chronic liver disease in…”
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Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice[S] by Tripathy, Sasmita, Lytle, Kelli A., Stevens, Robert D., Bain, James R., Newgard, Christopher B., Greenberg, Andrew S., Huang, Li-Shin, Jump, Donald B.

“…Nonalcoholic fatty liver disease is a major public health concern in the obese and type 2 diabetic populations. The high-fat lard diet induces obesity and…”
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A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male Ldlr -/- Mice by García-Jaramillo, Manuel, Lytle, Kelli A, Spooner, Melinda H, Jump, Donald B

“…Nonalcoholic fatty liver disease (NAFLD) is a major public health problem worldwide. NAFLD ranges in severity from benign steatosis to nonalcoholic…”
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Ceramide concentrations in liver, plasma, and very low‐density lipoproteins of humans with severe obesity by Lytle, Kelli A., Chung, Jin Ook, Bush, Nikki C., Triay, Jessica M., Jensen, Michael D.

“…We investigated the relationships between ceramide species concentrations in liver, plasma and very low‐density lipoproteins (VLDL) particles of humans with…”
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Insulin-Stimulated Muscle Glucose Uptake and Insulin Signaling in Lean and Obese Humans by Ramos, Paola A, Lytle, Kelli A, Delivanis, Danae, Nielsen, Søren, LeBrasseur, Nathan K, Jensen, Michael D

“…Abstract Purpose Skeletal muscle is the primary site for insulin-stimulated glucose disposal, and muscle insulin resistance is central to abnormal glucose…”
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Potential for Dietary ω-3 Fatty Acids to Prevent Nonalcoholic Fatty Liver Disease and Reduce the Risk of Primary Liver Cancer by Jump, Donald B, Depner, Christopher M, Tripathy, Sasmita, Lytle, Kelli A

“…Nonalcoholic fatty liver disease (NAFLD) has increased in parallel with central obesity, and its prevalence is anticipated to increase as the obesity epidemic…”
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Senescent cells in human adipose tissue: A cross‐sectional study by Espinosa De Ycaza, Ana Elena, Søndergaard, Esben, Morgan‐Bathke, Maria, Carranza Leon, Barbara Gisella, Lytle, Kelli A., Ramos, Paola, Kirkland, James L., Tchkonia, Tamar, Jensen, Michael D.

“…Objective Adipose tissue (AT) senescence is associated with AT dysfunction in rodents, but little is known about human AT senescence. The study goal was to…”
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Hepatic Fatty Acid Balance and Hepatic Fat Content in Humans With Severe Obesity by Lytle, Kelli A, Bush, Nikki C, Triay, Jessica M, Kellogg, Todd A, Kendrick, Michael L, Swain, James M, Gathaiya, Nicola W, Hames, Kazanna C, Jensen, Michael D

“…Nonalcoholic fatty liver disease can lead to hepatic inflammation/damage. Understanding the physiological mechanisms that contribute to excess hepatic lipid…”
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Adipocyte Proteins and Storage of Endogenous Fatty Acids in Visceral and Subcutaneous Adipose Tissue in Severe Obesity by Lytle, Kelli A., Bush, Nikki C., Triay, Jessica M., Kellogg, Todd A., Kendrick, Michael L., Swain, James M., Gathaiya, Nicola W., Hames, Kazanna C., Jensen, Michael D.

“…Objective This study tested whether substrate concentrations or fatty acid storage proteins predict storage of endogenous lipids in visceral adipose tissue…”
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The Soluble Fiber α-Cyclodextrin Does Not Increase the Fecal Losses of Dietary Fat in Adults-A Double-Blind, Randomized, Placebo-Controlled, Crossover Trial by Lytle, Kelli A, Harteneck, Debra A, Noble, Anthony M, Jensen, Michael D

“…α-Cyclodextrin (α-CD), a soluble dietary fiber, may improve abnormal plasma lipids and promote weight loss. Preliminary evidence suggests that it may exert…”
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Dietary docosahexaenoic acid (DHA) halts progression of nonalcoholic steatohepatitis (NASH), but does not promote fibrosis remission in Ldlr −/− mice by Lytle, Kelli A., Wong, Carmen, Jump, Donald

“…Abstract only Nonalcoholic fatty liver disease (NAFLD) is a major public health concern. NASH, the progressive form of NAFLD, is characterized by…”
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Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr.sup.-/- Mice Reversible? by Lytle, Kelli A, Jump, Donald B

“…Background Nonalcoholic fatty liver disease (NAFLD) is a major public health burden in western societies. The progressive form of NAFLD, nonalcoholic…”
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Potential for Dietary ω-3 Fatty Acids to Prevent Nonalcoholic Fatty Liver Disease and Reduce the Risk of Primary Liver Cancer123 by Jump, Donald B, Depner, Christopher M, Tripathy, Sasmita, Lytle, Kelli A

“…Nonalcoholic fatty liver disease (NAFLD) has increased in parallel with central obesity, and its prevalence is anticipated to increase as the obesity epidemic…”
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Hepatic Fatty Acid Balance and Hepatic Fat Content in Severely Obese Humans by Lytle, Kelli A, Bush, Nikki C, Triay, Jessica M, Kellogg, Todd A, Kendrick, Michael L, Swain, James M, Gathaiya, Nicola W, Hames, Kazanna C, Jensen, Michael D

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