Search Results - "Lyons, Yasmin A"
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Sequencing of mutational hotspots in cancer-related genes in small cell neuroendocrine cervical cancer
Published in Gynecologic oncology (01-06-2016)“…Abstract Objectives Small cell cervical cancer is a rare malignancy with limited treatment options for recurrent disease. We sought to determine if tumor…”
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Combined VEGFR and MAPK pathway inhibition in angiosarcoma
Published in Scientific reports (30-04-2021)“…Angiosarcoma is an aggressive malignancy of endothelial cells that carries a high mortality rate. Cytotoxic chemotherapy can elicit clinical responses, but the…”
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Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy
Published in Oncotarget (14-11-2017)“…Anti-angiogenesis therapy has shown clinical benefit in patients with high-grade serous ovarian cancer (HGSC), but adaptive resistance rapidly emerges. Thus,…”
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Immune cell profiling in cancer: molecular approaches to cell-specific identification
Published in NPJ precision oncology (15-08-2017)“…The immune system has many important regulatory roles in cancer development and progression. Given the emergence of effective immune therapies against many…”
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Multimodal perioperative pain protocol for gynecologic laparotomy is associated with reduced hospital length of stay
Published in The journal of obstetrics and gynaecology research (01-03-2021)“…Objectives The primary objective was to evaluate the impact of a multimodal perioperative pain regimen on length of hospital stay for patients undergoing…”
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Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers
Published in Cell reports (Cambridge) (01-11-2016)“…Even though hyperthermia is a promising treatment for cancer, the relationship between specific temperatures and clinical benefits and predictors of…”
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Response to MEK inhibitor in small cell neuroendocrine carcinoma of the cervix with a KRAS mutation
Published in Gynecologic oncology reports (01-12-2014)“…Highlights • Molecular testing may play a role in the determination of targeted therapy treatment options. • Targeted therapy provides treatment options for…”
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Perioperative inhibition of β-adrenergic and COX2 signaling in a clinical trial in breast cancer patients improves tumor Ki-67 expression, serum cytokine levels, and PBMCs transcriptome
Published in Brain, behavior, and immunity (01-10-2018)“…•Even before surgery, we observed pro-inflammatory/pro-metastatic responses in breast cancer patients.•Propranolol (β-blocker) and etodolac (COX2 inhibitor)…”
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Gynecologic Oncology: Challenges of Minimally Invasive Surgery In a Field of Maximal Complexities
Published in Clinical obstetrics and gynecology (01-03-2020)“…Minimally invasive surgery has become a standard in the surgical treatment for many women with gynecologic cancers. Within the scope of minimally invasive…”
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Abstract 723: Distinguishing macrophages by a unique gene signature to measure response to treatment
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Objectives: Tumor-associated macrophage infiltration is associated with poor prognosis, making macrophage depletion an ideal therapy. This study aims…”
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A rectovaginal septum mass in a BRCA1 positive patient years after risk reducing surgery: A case report
Published in Gynecologic oncology reports (01-05-2021)“…•Rectovaginal septum mass in BRCA1 positive patient after risk reducing BSO years prior.•Papillary serous carcinoma presenting as a rectovaginal septum…”
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Non‐16/18 high‐risk HPV infection predicts disease persistence and progression in women with an initial interpretation of LSIL
Published in Cancer cytopathology (01-07-2015)“…BACKGROUND The current management strategy for women with low‐grade squamous intraepithelial lesions (LSILs) is inefficient and expensive because of the…”
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Certain fusion genes are associated with clinical outcomes in high grade serous ovarian cancer
Published in Gynecologic oncology (01-11-2020)Get full text
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Identification of novel long non-coding RNAs in ovarian cancer and their impact on overall survival
Published in Gynecologic oncology (01-11-2020)Get full text
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Multimodal perioperative pain protocol for Gynecologic Oncology laparotomy reduces length of hospital stay
Published in Gynecologic oncology (01-07-2019)Get full text
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Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP)
Published in Oncogene (08-02-2018)“…Anti-vascular endothelial growth factor (VEGF) therapy has demonstrated efficacy in treating human metastatic cancers, but therapeutic resistance is a…”
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Abstract A026: Identifying mechanisms to target in combination with trametinib to improve therapeutic efficacy in low-grade serous ovarian cancer
Published in Cancer research (Chicago, Ill.) (04-03-2024)“…Abstract Low-grade serous ovarian cancer (LGSOC) has recently been characterized as a unique subtype of ovarian cancer with distinct molecular characteristics,…”
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Abstract 788: Less is more: macrophage depletion via CSF1/CSF1R pathway improves anti-VEGF therapy after adaptive resistance
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Objectives: Anti-angiogenesis therapy shows clinical benefit in patients with high-grade serous ovarian cancer (HGSC), but adaptive resistance…”
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