Search Results - "Lyons, Michael J."
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Influence of young adult cognitive ability and additional education on later-life cognition
Published in Proceedings of the National Academy of Sciences - PNAS (05-02-2019)“…How and when education improves cognitive capacity is an issue of profound societal importance. Education and later-life education-related factors, such as…”
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Distinct Genetic Influences on Cortical Surface Area and Cortical Thickness
Published in Cerebral cortex (New York, N.Y. 1991) (01-11-2009)“…Neuroimaging studies examining the effects of aging and neuropsychiatric disorders on the cerebral cortex have largely been based on measures of cortical…”
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VETSA: The Vietnam Era Twin Study of Aging
Published in Twin research and human genetics (01-02-2013)“…The Vietnam Era Twin Study of Aging (VETSA) is a longitudinal behavioral genetic study with a primary focus on cognitive and brain aging in men. It comprises a…”
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Genetic topography of brain morphology
Published in Proceedings of the National Academy of Sciences - PNAS (15-10-2013)“…Animal data show that cortical development is initially patterned by genetic gradients largely along three orthogonal axes. We previously reported differences…”
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Hierarchical Genetic Organization of Human Cortical Surface Area
Published in Science (American Association for the Advancement of Science) (30-03-2012)“…Surface area of the cerebral cortex is a highly heritable trait, yet little is known about genetic influences on regional cortical differentiation in humans…”
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Long-term blood pressure patterns in midlife and dementia in later life: Findings from the Framingham Heart Study
Published in Alzheimer's & dementia (01-10-2023)“…Long-term blood pressure (BP) measures, such as visit-to-visit BP variability (BPV) and cumulative BP, are strong indicators of cardiovascular risks. This…”
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Multimedia screening of contaminants of emerging concern (CECS) in coastal urban watersheds in southern California (USA)
Published in Environmental toxicology and chemistry (01-08-2016)“…To examine the occurrence and fate of contaminants of emerging concern (CECs) and inform future monitoring of CECs in coastal urban waterways, water, sediment,…”
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A Traitlike Dimension of Subjective Memory Concern Over 30 Years Among Adult Male Twins
Published in JAMA psychiatry (Chicago, Ill.) (01-07-2023)“…Subjective memory concern has long been considered a state-related indicator of impending cognitive decline or dementia. The possibility that subjective memory…”
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Associations between depression and cardiometabolic health: A 27-year longitudinal study
Published in Psychological medicine (01-10-2022)“…Clarifying the relationship between depression symptoms and cardiometabolic and related health could clarify risk factors and treatment targets. The objective…”
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Genetic Influences on Cortical Regionalization in the Human Brain
Published in Neuron (Cambridge, Mass.) (17-11-2011)“…Animal data demonstrate that the development of distinct cortical areas is influenced by genes that exhibit highly regionalized expression patterns. In this…”
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Interactive effects of testosterone and cortisol on hippocampal volume and episodic memory in middle-aged men
Published in Psychoneuroendocrinology (01-05-2018)“…•Research suggests that testosterone influences hippocampal structure and function.•The interaction of testosterone with other hormones is rarely…”
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Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia
Published in Nature communications (12-10-2018)“…Germline mutations in the ubiquitously expressed ACTB , which encodes β-cytoplasmic actin (CYA), are almost exclusively associated with Baraitser-Winter…”
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The Genetic Association Between Neocortical Volume and General Cognitive Ability Is Driven by Global Surface Area Rather Than Thickness
Published in Cerebral cortex (New York, N.Y. 1991) (01-08-2015)“…Total gray matter volume is associated with general cognitive ability (GCA), an association mediated by genetic factors. It is expectable that total…”
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Evidence and a Computational Explanation of Cultural Differences in Facial Expression Recognition
Published in Emotion (Washington, D.C.) (01-12-2010)“…Facial expressions are crucial to human social communication, but the extent to which they are innate and universal versus learned and culture dependent is a…”
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occurrence and fate of chemicals of emerging concern in coastal urban rivers receiving discharge of treated municipal wastewater effluent
Published in Environmental toxicology and chemistry (01-02-2014)“…To inform future monitoring and assessment of chemicals of emerging concern (CECs) in coastal urban watersheds, the occurrence and fate of more than 60…”
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Cognitive Reserve and Related Constructs: A Unified Framework Across Cognitive and Brain Dimensions of Aging
Published in Frontiers in aging neuroscience (27-05-2022)“…Cognitive reserve and related constructs are valuable for aging-related research, but consistency and clarification of terms is needed as there is still no…”
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Body mass trajectories and cortical thickness in middle-aged men: a 42-year longitudinal study starting in young adulthood
Published in Neurobiology of aging (01-07-2019)“…Evidence strongly suggests that being overweight or obese at midlife confers significantly higher risk for Alzheimer's disease and greater brain atrophy later…”
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Genetic and environmental influences on the size of specific brain regions in midlife: The VETSA MRI study
Published in NeuroImage (Orlando, Fla.) (15-01-2010)“…The impact of genetic and environmental factors on human brain structure is of great importance for understanding normative cognitive and brain aging as well…”
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Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome
Published in Clinical epigenetics (27-04-2019)“…ADNP syndrome is a rare Mendelian disorder characterized by global developmental delay, intellectual disability, and autism. It is caused by truncating…”
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Moderate Alcohol Use Is Associated with Reduced Cardiovascular Risk in Middle-Aged Men Independent of Health, Behavior, Psychosocial, and Earlier Life Factors
Published in Nutrients (24-05-2022)“…We examined whether the often-reported protective association of alcohol with cardiovascular disease (CVD) risk could arise from confounding. Our sample…”
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