Search Results - "Lyons, J.G."

PO-100: E6 viral protein ratio correlates with outcomes in human papillomavirus related oropharyngeal cancer by Hong, A, Zhang, X, Jones, D, Zhang, M, Lee, C.S, Lyons, J.G, Veillard, A.S, Rose, B

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O49. Snail1 and Snail2 inhibit the terminal differentiation of oral squamous cell carcinoma cells by repressing genes required for cornified envelope formation and release by Delic, N.C, Sou, P.W, Halliday, G.M, Lyons, J.G

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O48. Radiation-induced cell death of keratinocytes is enhanced by HPV16 oncoprotein E6∗ I: A possible mechanism for the improved clinical outcome of HPV positive oropharyngeal squamous cell carcinoma patients by Pang, E, Delic, N.C, Hong, A, Zhang, M, Rose, B.R, Lyons, J.G

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Transforming growth factor-beta 1 up-regulates type IV collagenase expression in cultured human keratinocytes by Salo, T, Lyons, J G, Rahemtulla, F, Birkedal-Hansen, H, Larjava, H

“…During the wound healing process lysis of basement membranes precedes keratinocyte migration into the wound bed. We studied, in vitro, whether this degradation…”
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Animal and translational models of SARS-CoV-2 infection and COVID-19 by Johansen, M. D., Irving, A., Montagutelli, X., Tate, M. D., Rudloff, I., Nold, M. F., Hansbro, N. G., Kim, R. Y., Donovan, C., Liu, G., Faiz, A., Short, K. R., Lyons, J. G., McCaughan, G. W., Gorrell, M. D., Cole, A., Moreno, C., Couteur, D., Hesselson, D., Triccas, J., Neely, G. G., Gamble, J. R., Simpson, S. J., Saunders, B. M., Oliver, B. G., Britton, W. J., Wark, P. A., Nold-Petry, C. A., Hansbro, P. M.

“…COVID-19 is causing a major once-in-a-century global pandemic. The scientific and clinical community is in a race to define and develop effective preventions…”
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Interleukin-1 beta and transforming growth factor-alpha/epidermal growth factor induce expression of M(r) 95,000 type IV collagenase/gelatinase and interstitial fibroblast-type collagenase by rat mucosal keratinocytes by Lyons, J.G., Birkedal-Hansen, B., Pierson, M.C., Whitelock, J.M., Birkedal-Hansen, H.

“…Rat mucosal keratinocytes serially propagated under permanently serum-free conditions responded to interleukin (IL)-1 beta/IL-alpha and to transforming growth…”
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Absolute quantitation of specific mRNAs in cell and tissue samples by comparative PCR by Martorana, A M, Zheng, G, Springall, F, Iland, H J, O'Grady, R L, Lyons, J G

“…A comparative PCR assay, for the absolute quantitation of specific mRNAs in cell and tissue samples, has been designed to overcome problems with previous…”
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BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours: Loss of BRM and BRG1 in skin cancer by Bock, V.L., Lyons, J.G., Huang, X.X.J., Jones, A.M., McDonald, L.A., Scolyer, R.A., Moloney, F.J., Barnetson, R.StC, Halliday, G.M.

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BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours by Bock, V.L., Lyons, J.G., Huang, X.X.J., Jones, A.M., McDonald, L.A., Scolyer, R.A., Moloney, F.J., Barnetson, R.StC, Halliday, G.M.

“…Summary Background  Nonmelanoma skin cancer is caused by exposure to ultraviolet radiation within sunlight. Actinic keratoses (AKs) are benign precursor…”
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O126. Cooperation between cancer cell clones: A new paradigm for the malignant progression of carcinomas by Lyons, J.G., Lobo, E., Myerscough, M.R.

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O47. The epithelial-mesenchymal transition inducer, Snail, inhibits terminal differentiation and promotes inflammation and invasion in squamous cell carcinomas by Lyons, J.G., Roue, N., Patel, V., Gutkind, J.S., Halliday, G.M.

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The interaction of metal ions and Marimastat with matrix metalloproteinase 9 by Underwood, C.K., Min, D., Lyons, J.G., Hambley, T.W.

“…The effect of a range of metal ions on the ability of Marimastat to inhibit matrix metalloproteinase 9 (MMP-9) was examined in a fluorescence based proteolytic…”
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Rat carcinoma cells in long-term, serum-free culture provide a continuing supply of collagenase by Stevenson, G A, Lyons, J G, Cameron, D A, O'Grady, R L

“…Neoplastic, epithelial cells derived from a spontaneously-arising rat mammary carcinoma have been cultured in a defined medium, in the absence of serum,…”
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