Search Results - "Lyon, David C"

A Disynaptic Relay from Superior Colliculus to Dorsal Stream Visual Cortex in Macaque Monkey by Lyon, David C., Nassi, Jonathan J., Callaway, Edward M.

“…The superior colliculus (SC) is the first station in a subcortical relay of retinal information to extrastriate visual cortex. Ascending SC projections pass…”
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Projections between visual cortex and pulvinar in the rat by Scholl, Leo R., Foik, Andrzej T., Lyon, David C.

“…The extrageniculate visual pathway, which carries visual information from the retina through the superficial layers of the superior colliculus and the…”
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Brain-wide reconstruction of inhibitory circuits after traumatic brain injury by Frankowski, Jan C., Tierno, Alexa, Pavani, Shreya, Cao, Quincy, Lyon, David C., Hunt, Robert F.

“…Despite the fundamental importance of understanding the brain’s wiring diagram, our knowledge of how neuronal connectivity is rewired by traumatic brain injury…”
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In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration by Choi, Elliot H., Suh, Susie, Foik, Andrzej T., Leinonen, Henri, Newby, Gregory A., Gao, Xin D., Banskota, Samagya, Hoang, Thanh, Du, Samuel W., Dong, Zhiqian, Raguram, Aditya, Kohli, Sajeev, Blackshaw, Seth, Lyon, David C., Liu, David R., Palczewski, Krzysztof

“…Leber congenital amaurosis (LCA) is the most common cause of inherited retinal degeneration in children. LCA patients with RPE65 mutations show accelerated…”
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Monosynaptic Restriction of Transsynaptic Tracing from Single, Genetically Targeted Neurons by Wickersham, Ian R., Lyon, David C., Barnard, Richard J.O., Mori, Takuma, Finke, Stefan, Conzelmann, Karl-Klaus, Young, John A.T., Callaway, Edward M.

“…There has never been a wholesale way of identifying neurons that are monosynaptically connected either to some other cell group or, especially, to a single…”
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Orientation Tuning of the Suppressive Extraclassical Surround Depends on Intrinsic Organization of V1 by Hashemi-Nezhad, Maziar, Lyon, David C.

“…The intrinsic functional architecture of early cortical areas in highly visual mammals is characterized by the presence of domains and pinwheels, with…”
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Tracing Inputs to Inhibitory or Excitatory Neurons of Mouse and Cat Visual Cortex with a Targeted Rabies Virus by Liu, Yong-Jun, Ehrengruber, Markus U., Negwer, Moritz, Shao, Han-Juan, Cetin, Ali H., Lyon, David C.

“…Background: Cortical inhibition plays a critical role in controlling and modulating cortical excitation, and a more detailed understanding of the neuronal…”
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case for primate V3 by Lyon, David C, Connolly, Jason D

“…The visual system in primates is represented by a remarkably large expanse of the cerebral cortex. While more precise investigative studies that can be…”
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Pulvinar contributions to the dorsal and ventral streams of visual processing in primates by Kaas, Jon H, Lyon, David C

“…Abstract The visual pulvinar is part of the dorsal thalamus, and in primates it is especially well developed. Recently, our understanding of how the visual…”
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Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision by Lewandowski, Dominik, Foik, Andrzej T, Smidak, Roman, Choi, Elliot H, Zhang, Jianye, Hoang, Thanh, Tworak, Aleksander, Suh, Susie, Leinonen, Henri, Dong, Zhiqian, Pinto, Antonio Fm, Tom, Emily, Luu, Jennings, Lee, Joan, Ma, Xiuli, Bieberich, Erhard, Blackshaw, Seth, Saghatelian, Alan, Lyon, David C, Skowronska-Krawczyk, Dorota, Tabaka, Marcin, Palczewski, Krzysztof

“…Adiponectin receptor 1 (ADIPOR1) is a lipid and glucose metabolism regulator that possesses intrinsic ceramidase activity. Mutations of the ADIPOR1 gene have…”
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Traumatic brain injury to primary visual cortex produces long-lasting circuit dysfunction by Frankowski, Jan C., Foik, Andrzej T., Tierno, Alexa, Machhor, Jiana R., Lyon, David C., Hunt, Robert F.

“…Primary sensory areas of the mammalian neocortex have a remarkable degree of plasticity, allowing neural circuits to adapt to dynamic environments. However,…”
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Dynamics of extraclassical surround modulation in three types of V1 neurons by Liu, Yong-Jun, Hashemi-Nezhad, Maziar, Lyon, David C

“…Visual stimuli outside of the classical receptive field (CRF) can influence the response of neurons in primary visual cortex (V1). While recording single units…”
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Functional organization of motor cortex of adult macaque monkeys is altered by sensory loss in infancy by Qi, Hui-Xin, Jain, Neeraj, Collins, Christine E, Lyon, David C, Kaas, Jon H

“…When somatosensory cortex (S1) is deprived of some of its inputs after section of ascending afferents in the dorsal columns of the spinal cord, it reorganizes…”
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Connectional and Architectonic Evidence for Dorsal and Ventral V3, and Dorsomedial Area in Marmoset Monkeys by Lyon, David C, Kaas, Jon H

“…The existence of a third visual area, V3, along the outer margin of V2 was originally proposed for primates on the basis of projections from V1. The evidence…”
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Visual Response Characteristics in Lateral and Medial Subdivisions of the Rat Pulvinar by Foik, Andrzej T., Scholl, Leo R., Lean, Georgina A., Lyon, David C.

“…[Display omitted] •Pulvinar (LP) neurons share some features of V1 neurons in rodent.•1/4 of LP cells were tuned to orientation, compared to 1/2 in V1.•Larger…”
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Cortical and thalamic connections of the parietal ventral somatosensory area in marmoset monkeys (Callithrix jacchus) by Qi, Hui-Xin, Lyon, David C., Kaas, Jon H.

“…Microelectrode mapping methods were used to define the parietal ventral somatosensory area (PV) on the upper bank of the lateral sulcus in five marmosets…”
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Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing by Suh, Susie, Choi, Elliot H., Leinonen, Henri, Foik, Andrzej T., Newby, Gregory A., Yeh, Wei-Hsi, Dong, Zhiqian, Kiser, Philip D., Lyon, David C., Liu, David R., Palczewski, Krzysztof

“…Cytosine base editors and adenine base editors (ABEs) can correct point mutations predictably and independent of Cas9-induced double-stranded DNA breaks (which…”
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Cell type specific tracing of the subcortical input to primary visual cortex from the basal forebrain by Lean, Georgina A., Liu, Yong‐Jun, Lyon, David C.

“…The basal forebrain provides cholinergic inputs to primary visual cortex (V1) that play a key modulatory role on visual function. While basal forebrain…”
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Stress induced aging in mouse eye by Xu, Qianlan, Rydz, Cezary, Nguyen Huu, Viet Anh, Rocha, Lorena, Palomino La Torre, Claudia, Lee, Irene, Cho, William, Jabari, Mary, Donello, John, Lyon, David C., Brooke, Robert T., Horvath, Steve, Weinreb, Robert N., Ju, Won‐Kyu, Foik, Andrzej, Skowronska‐Krawczyk, Dorota

“…Aging, a universal process that affects all cells in an organism, is a major risk factor for a group of neuropathies called glaucoma, where elevated…”
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V1 connections reveal a series of elongated higher visual areas in the California ground squirrel, Otospermophilus beecheyi by Negwer, Moritz, Liu, Yong‐Jun, Schubert, Dirk, Lyon, David C.

“…For studies of visual cortex organization, mouse is becoming an increasingly more often used model. In addition to its genetic tractability, the relatively…”
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