Search Results - "Lynn, Helen E."

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  1. 1

    Deactivation of Sphingosine Kinase 1 by Protein Phosphatase 2A by Barr, Renae K., Lynn, Helen E., Moretti, Paul A.B., Khew-Goodall, Yeesim, Pitson, Stuart M.

    Published in The Journal of biological chemistry (12-12-2008)
    “…Sphingosine kinase 1 (SK1) is an important regulator of cellular signaling that has been implicated in a broad range of cellular processes. Cell exposure to a…”
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    Journal Article
  2. 2

    Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation by Pitson, Stuart M, Moretti, Paul A.B, Zebol, Julia R, Lynn, Helen E, Xia, Pu, Vadas, Mathew A, Wattenberg, Binks W

    Published in The EMBO journal (15-10-2003)
    “…Sphingosine kinase 1 is an agonist‐activated signalling enzyme that catalyses the formation of sphingosine 1‐phosphate, a lipid second messenger that has been…”
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    Journal Article
  3. 3

    Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling by Pitson, Stuart M, Xia, Pu, Leclercq, Tamara M, Moretti, Paul A B, Zebol, Julia R, Lynn, Helen E, Wattenberg, Binks W, Vadas, Mathew A

    Published in The Journal of experimental medicine (03-01-2005)
    “…Sphingosine kinase (SK) 1 catalyzes the formation of the bioactive lipid sphingosine 1-phosphate, and has been implicated in several biological processes in…”
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    Journal Article
  4. 4

    The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1 by Zebol, Julia R., Hewitt, Niamh M., Moretti, Paul A.B., Lynn, Helen E., Lake, Julie A., Li, Peng, Vadas, Mathew A., Wattenberg, Binks W., Pitson, Stuart M.

    “…Sphingosine kinase 1 (SK1) catalyses the generation of sphingosine 1-phosphate (S1P), a bioactive phospholipid that influences a diverse range of cellular…”
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    Journal Article
  5. 5