Search Results - "Lynn, Helen E."
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Deactivation of Sphingosine Kinase 1 by Protein Phosphatase 2A
Published in The Journal of biological chemistry (12-12-2008)“…Sphingosine kinase 1 (SK1) is an important regulator of cellular signaling that has been implicated in a broad range of cellular processes. Cell exposure to a…”
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Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation
Published in The EMBO journal (15-10-2003)“…Sphingosine kinase 1 is an agonist‐activated signalling enzyme that catalyses the formation of sphingosine 1‐phosphate, a lipid second messenger that has been…”
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Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling
Published in The Journal of experimental medicine (03-01-2005)“…Sphingosine kinase (SK) 1 catalyzes the formation of the bioactive lipid sphingosine 1-phosphate, and has been implicated in several biological processes in…”
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The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1
Published in The international journal of biochemistry & cell biology (01-04-2009)“…Sphingosine kinase 1 (SK1) catalyses the generation of sphingosine 1-phosphate (S1P), a bioactive phospholipid that influences a diverse range of cellular…”
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