Search Results - "Lynn, Frances"

A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis by Polman, Chris H, O'Connor, Paul W, Havrdova, Eva, Hutchinson, Michael, Kappos, Ludwig, Miller, David H, Phillips, J. Theodore, Lublin, Fred D, Giovannoni, Gavin, Wajgt, Andrzej, Toal, Martin, Lynn, Frances, Panzara, Michael A, Sandrock, Alfred W

“…This placebo-controlled, randomized trial of patients with relapsing multiple sclerosis demonstrated benefits of natalizumab (an α 4 integrin antagonist) in…”
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Best practice for analysis of shared clinical trial data by Hollis, Sally, Fletcher, Christine, Lynn, Frances, Urban, Hans-Joerg, Branson, Janice, Burger, Hans-Ulrich, Tudur Smith, Catrin, Sydes, Matthew R, Gerlinger, Christoph

“…Greater transparency, including sharing of patient-level data for further research, is an increasingly important topic for organisations who sponsor, fund and…”
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Zooarchaeological and palaeoenvironmental reconstruction of newly excavated Middle Pleistocene deposits from Elandsfontein, South Africa by Forrest, Frances Lynn

“…Increased consumption of animal tissue is arguably one of the most important adaptive transitions in early hominin behavior. A dietary shift toward regular…”
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Community-Scientist Collaboration in Environmental Research by LYNN, FRANCES M.

“…Community participation in governmental environmental decision making is firmly institutionalized. In recent years, citizens have also demanded involvement in…”
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Timed 25-Foot Walk: Direct evidence that improving 20% or greater is clinically meaningful in MS by HOBART, Jeremy, BLIGHT, Andrew R, GOODMAN, Andrew, LYNN, Frances, PUTZKI, Norman

“…In this study, we used data from clinical trials of dalfampridine (fampridine outside the United States) to re-examine the clinical meaningfulness of Timed…”
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Chemical Industry's Community Advisory Panels:  What Has Been Their Impact? by Lynn, Frances M, Busenberg, George, Cohen, Nevin, Chess, Caron

“…The American chemical industry is sponsoring over 300 community advisory panels (CAPs) at plants across the country to repair lost trust and credibility. CAPs…”
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Natalizumab plus Interferon Beta-1a for Relapsing Multiple Sclerosis by Rudick, Richard A, Stuart, William H, Calabresi, Peter A, Confavreux, Christian, Galetta, Steven L, Radue, Ernst-Wilhelm, Lublin, Fred D, Weinstock-Guttman, Bianca, Wynn, Daniel R, Lynn, Frances, Panzara, Michael A, Sandrock, Alfred W

“…In this randomized trial involving patients with relapsing multiple sclerosis who had had relapses despite treatment with interferon, natalizumab in…”
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Linking the Community and the University by Lynn, Frances M

“…Discusses research and service collaborations between universities and community-based organizations. Examines factors that promote effective…”
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Health-related quality of life in multiple sclerosis: effects of natalizumab by Rudick, Richard A., Miller, Deborah, Hass, Steve, Hutchinson, Michael, Calabresi, Peter A., Confavreux, Christian, Galetta, Steven L., Giovannoni, Gavin, Havrdova, Eva, Kappos, Ludwig, Lublin, Fred D., Miller, David H., O'Connor, Paul W., Phillips, J. Theodore, Polman, Chris H., Radue, Ernst-Wilhelm, Stuart, William H., Wajgt, Andrzej, Weinstock-Guttman, Bianca, Wynn, Daniel R., Lynn, Frances, Panzara, Michael A.

“…Objective To report the relationship between disease activity and health‐related quality of life (HRQoL) in relapsing multiple sclerosis, and the impact of…”
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The efficacy of natalizumab in patients with relapsing multiple sclerosis: subgroup analyses of AFFIRM and SENTINEL by Hutchinson, M., Kappos, L., Calabresi, P. A., Confavreux, C., Giovannoni, G., Galetta, S. L., Havrdova, E., Lublin, F. D., Miller, D. H., O’Connor, P. W., Phillips, J. T., Polman, C. H., Radue, E.-W., Rudick, R. A., Stuart, W. H., Wajgt, A., Weinstock-Guttman, B., Wynn, D. R., Lynn, F., Panzara, M. A.

“…The AFFIRM and SENTINEL studies showed that natalizumab was effective both as monotherapy and in combination with interferon beta (IFNβ)-1a in patients with…”
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Lentiviral Gene Therapy with Autologous Hematopoietic Stem and Progenitor Cells (HSPCs) for the Treatment of Severe Combined Immune Deficiency Due to Adenosine Deaminase Deficiency (ADA-SCID): Results in an Expanded Cohort by Kohn, Donald B., Shaw, Kit L., Garabedian, Elizabeth, Carbonaro-Sarracino, Denise Ann, Moore, Theodore B., De Oliveira, Satiro N., Crooks, Gay M., Tse, John, Shupien, Sally, Terrazas, Dayna, Davila, Alejandra, Icreverzi, Amalia, Yu, Allen, Chun, Krista M., Casas, Christian E., Barman, Provaboti, Coronel, Maritess, Campo Fernandez, Beatriz, Zhang, Ruixue, Hollis, Roger P., Uzowuru, Chilenwa, Ricketts, Hilory, Bayford, Jinhua Xu, Trevisan, Valentina, Arduini, Serena, Lynn, Frances, Kudari, Mahesh, Spezzi, Andrea, Reeves, Lilith, Cornetta, Kenneth, Sokolic, Robert A., Parrott, Roberta, Buckley, Rebecca, Booth, Claire, Candotti, Fabio, Malech, Harry L., Thrasher, Adrian J., Gaspar, H. Bobby

“…Background: Severe combined immunodeficiency due to adenosine deaminase deficiency (ADA-SCID) is a rare disorder caused by ADA gene mutations, leading to…”
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Additional efficacy endpoints from pivotal natalizumab trials in relapsing-remitting MS by Weinstock-Guttman, Bianca, Galetta, Steven L., Giovannoni, Gavin, Havrdova, Eva, Hutchinson, Michael, Kappos, Ludwig, O’Connor, Paul W., Phillips, J. Theodore, Polman, Chris, Stuart, William H., Lynn, Frances, Hotermans, Christophe

“…Standard clinical endpoints in multiple sclerosis (MS) studies, such as disability progression defined by the expanded disability status scale (EDSS) and…”
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Paracellular Transport of Soybean β‐Conglycinin using a Caco‐2/HT29‐MTX Co‐Culture by Wallace, Frances Lynn, Mahler, Gretchen J., Tan‐Wilson, Anna, Wilson, Karl A.

“…Abstract only Soybeans are one of the eight most prevalent food allergens and the β‐conglycinins have been determined to be one of the allergenic proteins…”
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Changes in NLRP3 Inflammasome After Mindfulness Training: An Ancillary Analysis of Data from the Shine Randomized Clinical Trial by Kutler, Lynn Frances

“…This ancillary analysis of data from the SHINE randomized clinical trial investigated the relationships between perceived stress, trait mindfulness, and NLRP3…”
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The Interplay of Science and Values in Assessing and Regulating Environmental Risks by Lynn, Frances M.

“…Focuses on role of science and scientists in the decisionmaking process for determining whether a product or technology is acceptably safe…”
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Expansion Thoracoplasty as a Life-Saving Procedure in an Adolescent With Severe Spinal Deformity and Sacral Agenesis by Mathews, Chelsea S, Bumpass, David B, McCullough, Frances Lynn, McCarthy, Richard E

“…Case report. To describe use of expansion thoracoplasty (ET) for severe thoracic insufficiency syndrome (TIS) in an adolescent with severe spinal deformity. ET…”
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Serotonin Functioning and Adolescents' Alcohol Use: A Genetically Informed Study Examining Mechanisms of Risk by Wang, Frances Lynn

“…The current study utilized data from two longitudinal samples to test mechanisms in the relation between a polygenic risk score indexing serotonin functioning…”
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XGBoost-Based Analysis of the Early-Stage Diabetes Risk Dataset by Sabejon, Jayson A., Rejas, Jeyhozaphat B., Lumacad, Gernel S., Zarate, Reymund L., Mendez, Edwin Anthony D., Tinoy, Frances Marie Lynn O.

“…Diabetes is a metabolic condition caused by either a lack of insulin production from the pancreas or insufficient utilization of insulin by the body. It is…”
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Practical Application of an Indigenous Research Framework and Two Qualitative Indigenous Research Methods: Sharing Circles and Anishnabe Symbold-Based Reflection by Canada, Lynn Frances Lavallee

“…Increasingly, research involving Indigenous people is being undertaken by Indigenous researchers, who bring forward world views that shape the approach of the…”
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A Pilot Study Assessing the Relationship Between Child Harming Thoughts and Postpartum Depression by Humenik, Amy Lynn Frances, Fingerhut, Randy

“…This pilot study explored relationships between postpartum mood and child harming thoughts. Fifty mothers from an outpatient pediatric office completed the…”
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