Search Results - "Lynn, Bert"
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Application of lithium cationization tandem mass spectrometry for structural analysis of lignin model oligomers with β-β′ and β-O-4′ linkages
Published in Analytical and bioanalytical chemistry (01-08-2022)“…Structural elucidation of lignin degradation products is a requirement for successfully developing lignin valorization technology. Most of mass…”
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Pretreatment of lignocellulosic biomass using Fenton chemistry
Published in Bioresource technology (01-06-2014)“…•We investigated the viability of Fenton chemistry for biomass pretreatment.•We assessed pretreatment using enzymatic and microbial fermentation…”
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Characterization and sequencing of lithium cationized β-O-4 lignin oligomers using higher-energy collisional dissociation mass spectrometry
Published in Analytica chimica acta (24-01-2019)“…The prospect of developing new bio-based products from lignin partially depends on the development of effective analytical techniques to characterize the end…”
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Application of Chloride Adduct Ionization Tandem Mass Spectrometry for Characterizing and Sequencing Synthetic Lignin Model Compounds
Published in Energy & fuels (17-05-2018)“…The need for renewable bioenergy sources has renewed interest in lignin chemistry; however, structural elucidation and characterization of lignin degradation…”
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Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry analysis for characterization of lignin oligomers using cationization techniques and 2,5‐dihydroxyacetophenone (DHAP) matrix
Published in Rapid communications in mass spectrometry (30-04-2019)“…Rationale Effective analytical techniques are needed to characterize lignin products for the generation of renewable carbon sources. Application of…”
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Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease
Published in Neurobiology of aging (01-08-2006)“…Previous studies show increased levels of lipid peroxidation and neurotoxic by-products of lipid peroxidation including 4-hydroxynonenal (HNE) and acrolein in…”
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The study of the chromatographic behavior and a mass spectrometric approach to differentiating the diastereomer pair of the β-O-4 lignin dimer series
Published in Analytical and bioanalytical chemistry (01-06-2021)“…Lignin and lignans are natural products found in plant cell walls. Lignin research has historically focused on lignin degradation techniques in the hope of…”
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A comparative study of the electrospray ionization response of β‐O‐4′ lignin model compounds
Published in Journal of mass spectrometry. (01-06-2019)“…Electrospray ionization mass spectrometry has recently become the technique of choice for rapid characterization of lignin degradation products. However, the…”
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Nucleic acid oxidation: an early feature of Alzheimer's disease
Published in Journal of neurochemistry (01-01-2014)“…Studies of oxidative damage during the progression of Alzheimer's disease (AD) suggest its central role in disease pathogenesis. To investigate levels of…”
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Understanding Laccase–Ionic Liquid Interactions toward Biocatalytic Lignin Conversion in Aqueous Ionic Liquids
Published in ACS sustainable chemistry & engineering (07-10-2019)“…Lignin is a crucial component of plant matter; however, it is also largely responsible for the recalcitrance of lignocellulosic biomass when subjected to…”
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Microfluidic capillary zone electrophoresis mass spectrometry analysis of alkaloids in Lobelia cardinalis transgenic and mutant plant cell cultures
Published in Electrophoresis (01-11-2019)“…Application of a microfluidic CE* device for CZE‐MS allows for fast, rapid, and in‐depth analysis of large sample sets. This microfluidic CZE‐MS device, the…”
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Interaction of lignin-derived dimer and eugenol-functionalized silica nanoparticles with supported lipid bilayers
Published in Colloids and surfaces, B, Biointerfaces (01-07-2020)“…[Display omitted] •Silica nanoparticles functionalized with lignin molecules using click chemistry.•Interaction of nanoparticles with lipid bilayers…”
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Complexation of Lignin Dimers with β‑Cyclodextrin and Binding Stability Analysis by ESI-MS, Isothermal Titration Calorimetry, and Molecular Dynamics Simulations
Published in The journal of physical chemistry. B (03-03-2022)“…Lignin derived from lignocellulosic biomass is the largest source of renewable bioaromatics present on earth and requires environmentally sustainable…”
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Experimental and Molecular Dynamics Simulation Study of the Effects of Lignin Dimers on the Gel-to-Fluid Phase Transition in DPPC Bilayers
Published in The journal of physical chemistry. B (03-10-2019)“…High resolution differential scanning calorimetry (DSC) and molecular dynamics (MD) simulations were used to investigate the effect of three lignin dimers on…”
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Pharmacokinetic and metabolic analysis of an Alzheimer's disease therapeutic in rat serum via microfluidic CZE–MS
Published in Biomedical chromatography (01-01-2022)“…Sensitive, high‐throughput methods for pharmacokinetic (PK) profiling are essential for potential therapeutics during critical stages of clinical trials. The…”
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Antimicrobial Properties of Corn Stover Lignin Fractions Derived from Catalytic Transfer Hydrogenolysis in Supercritical Ethanol with a Ru/C Catalyst
Published in ACS sustainable chemistry & engineering (21-12-2020)“…Converting lignin to value-added products at high yields provides an avenue for making ethanol biorefineries more profitable while reducing the carbon…”
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An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice
Published in Nature medicine (01-11-2003)“…The study and treatment of age-related macular degeneration (AMD), a leading cause of blindness, has been hampered by a lack of animal models. Here we report…”
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Proteomic identification of nitrated proteins in Alzheimer's disease brain
Published in Journal of neurochemistry (01-06-2003)“…Nitration of tyrosine in biological conditions represents a pathological event that is associated with several neurodegenerative diseases, such as amyotrophic…”
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A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury
Published in Brain injury (23-02-2018)“…Background: Although elevated serum levels of visinin-like protein 1 (VILIP-1), a neuron-specific calcium sensor protein, are associated with ischaemic stroke,…”
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