Search Results - "Lyng, Fiona"
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Discrimination of breast cancer from benign tumours using Raman spectroscopy
Published in PloS one (14-02-2019)“…Breast cancer is the most common cancer among women worldwide, with an estimated 1.7 million cases and 522,000 deaths in 2012. Breast cancer is diagnosed by…”
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Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women's Health Issue-A Review
Published in Molecules (Basel, Switzerland) (01-03-2023)“…This review focuses on recent advances and future perspectives in the use of Raman spectroscopy for cervical cancer, a global women's health issue. Cervical…”
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3
Reactive oxygen species and nitric oxide signaling in bystander cells
Published in PloS one (05-04-2018)“…It is now well accepted that radiation induced bystander effects can occur in cells exposed to media from irradiated cells. The aim of this study was to follow…”
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4
Abscopal Effects, Clastogenic Effects and Bystander Effects: 70 Years of Non-Targeted Effects of Radiation
Published in Radiation research (01-08-2024)“…In vitro and in vivo observations accumulated over several decades have firmly shown that the biological effects of ionizing radiation can spread from…”
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Women's contributions to radiobiology in Ireland; from small beginnings
Published in International journal of radiation biology (2022)“…To describe the contribution of women radiobiologists in Ireland to the development of the discipline internationally and at home and to discuss the history of…”
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Surface Enhanced Raman Spectroscopy for Quantitative Analysis: Results of a Large-Scale European Multi-Instrument Interlaboratory Study
Published in Analytical chemistry (Washington) (03-03-2020)“…Surface-enhanced Raman scattering (SERS) is a powerful and sensitive technique for the detection of fingerprint signals of molecules and for the investigation…”
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Raman spectral cytopathology for cancer diagnostic applications
Published in Nature protocols (01-07-2021)“…Raman spectroscopy can provide a rapid, label-free, nondestructive measurement of the chemical fingerprint of a sample and has shown potential for cancer…”
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Raman spectroscopy for screening and diagnosis of cervical cancer
Published in Analytical and bioanalytical chemistry (01-11-2015)“…Cervical cancer is the fourth most common cancer in women worldwide and mainly affects younger women. The mortality associated with cervical cancer can be…”
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Mechanistic studies of in vitro cytotoxicity of poly(amidoamine) dendrimers in mammalian cells
Published in Toxicology and applied pharmacology (01-11-2010)“…Poly(amidoamine) (PAMAM) dendrimer nanoparticles have been demonstrated to elicit a well defined cytotoxicological response from mammalian cell lines, the…”
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10
Development of a high throughput (HT) Raman spectroscopy method for rapid screening of liquid blood plasma from prostate cancer patients
Published in Analyst (London) (10-04-2017)“…Extensive research has been undertaken on the examination of tissue biopsies using vibrational spectroscopic techniques. However, fewer studies have focused on…”
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Biomedical applications of vibrational spectroscopy: Oral cancer diagnostics
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-05-2021)“…[Display omitted] •Applications of vibrational spectroscopy to early stage diagnosis of oral disease are reviewed.•Ex-vivo analyses of excised tissue,…”
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Raman spectroscopic detection of high-grade cervical cytology: Using morphologically normal appearing cells
Published in Scientific reports (09-10-2018)“…This study aims to detect high grade squamous intraepithelial cells (HSIL) by investigating HSIL associated biochemical changes in morphologically normal…”
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13
Reactive oxygen species (ROS) induced cytokine production and cytotoxicity of PAMAM dendrimers in J774A.1 cells
Published in Toxicology and applied pharmacology (01-07-2010)“…The immunotoxicity of three generations of polyamidoamine (PAMAM) dendrimers (G-4, G-5 and G-6) was evaluated in mouse macrophage cells in vitro. Using the…”
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14
Apoptosis is signalled early by low doses of ionising radiation in a radiation-induced bystander effect
Published in Mutation research (01-01-2013)“…It is known that ionising radiation (IR) induces a complex signalling apoptotic cascade post-exposure to low doses ultimately to remove damaged cells from a…”
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15
Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study
Published in Analytical chemistry (Washington) (15-12-2020)“…The variable configuration of Raman spectroscopic platforms is one of the major obstacles in establishing Raman spectroscopy as a valuable physicochemical…”
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Correction: Discrimination of breast cancer from benign tumours using Raman spectroscopy
Published in PloS one (25-04-2019)“…[This corrects the article DOI: 10.1371/journal.pone.0212376.]…”
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The Potential of Raman Spectroscopy in the Diagnosis of Dysplastic and Malignant Oral Lesions
Published in Cancers (04-02-2021)“…Early diagnosis, treatment and/or surveillance of oral premalignant lesions are important in preventing progression to oral squamous cell carcinoma (OSCC). The…”
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In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells
Published in Toxicology in vitro (01-04-2007)“…This paper describes the in vitro cytotoxicity assessment of single walled carbon nanotubes (SWCNT) on A549 cells, a human lung cell line. Cellular viability…”
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Raman micro-spectroscopy for rapid screening of oral squamous cell carcinoma
Published in Experimental and molecular pathology (01-06-2015)“…Raman spectroscopy can provide a molecular-level fingerprint of the biochemical composition and structure of cells with excellent spatial resolution and could…”
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Application of Advanced Non-Linear Spectral Decomposition and Regression Methods for Spectroscopic Analysis of Targeted and Non-Targeted Irradiation Effects in an In-Vitro Model
Published in International journal of molecular sciences (01-11-2022)“…Irradiation of the tumour site during treatment for cancer with external-beam ionising radiation results in a complex and dynamic series of effects in both the…”
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