Search Results - "Lynch, S G"

Inflammation and altered metabolism impede efficacy of functional electrical stimulation in critically ill patients by Jameson, T S O, Caldow, M K, Stephens, F, Denehy, L, Lynch, G S, Koopman, R, Krajcova, A, Urban, T, Berney, S, Duska, F, Puthucheary, Z

“…Critically ill patients suffer from acute muscle wasting, which is associated with significant physical functional impairment. We describe data from nested…”
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Screening, Diagnosis and Management of Sarcopenia and Frailty in Hospitalized Older Adults: Recommendations from the Australian and New Zealand Society for Sarcopenia and Frailty Research (ANZSSFR) Expert Working Group by Daly, Robin M., Iuliano, S., Fyfe, J. J., Scott, D., Kirk, B., Thompson, M. Q., Dent, E., Fetterplace, K., Wright, O. R. L., Lynch, G. S., Zanker, J., Yu, S., Kurrle, S., Visvanathan, R., Maier, A. B.

“…Sarcopenia and frailty are highly prevalent conditions in older hospitalized patients, which are associated with a myriad of adverse clinical outcomes. This…”
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Comparative evaluation of IGF-I gene transfer and IGF-I protein administration for enhancing skeletal muscle regeneration after injury by SCHERTZER, J. D, LYNCH, G. S

“…Developing methodologies to enhance skeletal muscle regeneration and hasten the restoration of muscle function has important implications for minimizing…”
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Examination of ‘lipotoxicity’ in skeletal muscle of high‐fat fed and ob/ob mice by Turpin, S. M., Ryall, J. G., Southgate, R., Darby, I., Hevener, A. L., Febbraio, M. A., Kemp, B. E., Lynch, G. S., Watt, M. J.

“…Excess lipid accumulation resulting from an elevated supply of plasma fatty acids is linked to the pathogenesis of the metabolic syndrome and heart disease…”
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Tackling Australia's future health problems: developing strategies to combat sarcopenia − age-related muscle wasting and weakness by Lynch, G. S.

“…Some of the most serious consequences of ageing are its effects on skeletal muscle structure and function. Ageing is associated with a progressive loss of…”
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Fatigue in multiple sclerosis: relationship to depression, disability, and disease pattern by Kroencke, Dawn C, Lynch, Sharon G, Denney, Douglas R

“…In order to investigate the associations between fatigue and depression, disability, and disease subtype, 207 individuals with clinically definite Multiple…”
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Selective impairment of learning and blockade of long-term potentiation by an N -methyl-D-aspartate receptor antagonist, AP5 by Morris, R. G. M, Anderson, E, Lynch, G. S, Baudry, M

“…Recent work has shown that the hippocampus contains a class of receptors for the excitatory amino acid glutamate that are activated by N-methyl-D-aspartate…”
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Spectroscopic gas detection using a Bragg grating - stabilized external cavity laser, custom written in planar integrated silica-on-silicon by Davis, N. M., Lynch, S. G., Gates, J. C., Hodgkinson, J., Smith, P. G. R., Tatam, R. P.

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Prevalence of multiple sclerosis in a residential area bordering an oil refinery by NEUBERGER, J. S, LYNCH, S. G, SUTTON, M. L, HALL, S. B, FENG, C, SCHMIDT, W. R

“…Community concerns about a potential excess of multiple sclerosis (MS) prompted this study. To determine the period prevalence of MS in a community bordering a…”
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Lower levels of glutathione in the brains of secondary progressive multiple sclerosis patients measured by 1H magnetic resonance chemical shift imaging at 3 T by Choi, I-Y, Lee, S-P, Denney, DR, Lynch, SG

“…Background: Disability levels for patients with secondary progressive multiple sclerosis (SPMS) often worsen despite a stable MRI T2 lesion burden. The…”
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Hyperbaric oxygen modulates antioxidant enzyme activity in rat skeletal muscles by Gregorevic, P, Lynch, G S, Williams, D A

“…In skeletal muscle the activity of the enzymatic antioxidants superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) is regulated in…”
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In vivo and in vitro correction of the mdx dystrophin gene nonsense mutation by short-fragment homologous replacement by Kapsa, R, Quigley, A, Lynch, G S, Steeper, K, Kornberg, A J, Gregorevic, P, Austin, L, Byrne, E

“…Targeted genetic correction of mutations in cells is a potential strategy for treating human conditions that involve nonsense, missense, and transcriptional…”
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Leukemia inhibitory factor ameliorates muscle fiber degeneration in the mdx mouse by Austin, L., Bower, J. J., Bennett, T. M., Lynch, G. S., Kapsa, R., White, J. D., Barnard, W., Gregorevic, P., Byrne, E.

“…Although the muscles of the mdx mouse lack dystrophin, the protein absent in muscles of humans affected with Duchenne muscular dystrophy (DMD), the only mdx…”
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Spaced training improves learning in Ts65Dn and Ube3a mouse models of intellectual disabilities by Lauterborn, J. C., Schultz, M. N., Le, A. A., Amani, M., Friedman, A. E., Leach, P. T., Gall, C. M., Lynch, G. S., Crawley, J. N.

“…Benefits of distributed learning strategies have been extensively described in the human literature, but minimally investigated in intellectual disability…”
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Body metrics are associated with clinical, free-living, and self-report measures of mobility in a cohort of adults with obesity and multiple sclerosis by Cozart, J.S., Bruce, A.S., Shook, R.P., Befort, C., Siengsukon, C., Simon, S., Lynch, S.G., Mahmoud, R., Drees, B., Posson, P., Hibbing, P.R., Huebner, J., Bradish, T., Robichaud, J., Bruce, J.M.

“…•Higher BMI, waist-to-height ratio, and percentage body fat were associated with lower levels of mobility (Timed 25-foot Walk and Six-minute Walk Test) in…”
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Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice by Lynch, G S, Rafael, J A, Hinkle, R T, Cole, N M, Chamberlain, J S, Faulkner, J A

“…Diaphragm muscles of young (4- to 6-mo-old) mdx mice show severe fiber necrosis and have normalized forces and powers 60 and 46% of the values for control…”
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Muscle-specific deletion of SOCS3 does not reduce the anabolic response to leucine in a mouse model of acute inflammation by Caldow, M.K., Ham, D.J., Chee, A., Trieu, J., Naim, T., Stapleton, D.I., Swiderski, K., Lynch, G.S., Koopman, R.

“…•SOCS3 deletion in skeletal muscle does not alter LPS-induced inflammation.•SOCS3 does not mediate the anabolic response to leucine in skeletal muscle.•Leucine…”
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IGF-I treatment improves the functional properties of fast- and slow-twitch skeletal muscles from dystrophic mice by Lynch, Gordon S, Cuffe, Scott A, Plant, David R, Gregorevic, Paul

“…Although insulin-like growth factor-I (IGF-I) has been proposed for use by patients suffering from muscle wasting conditions, few studies have investigated the…”
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Deleterious effects of chronic clenbuterol treatment on endurance and sprint exercise performance in rats by Duncan, N D, Williams, D A, Lynch, G S

“…The beta(2)-adrenergic agonist, clenbuterol, has powerful muscle anabolic and lipolytic effects and is used by athletes to improve exercise performance;…”
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Duchenne muscular dystrophy: Focus on pharmaceutical and nutritional interventions by Radley, H.G., De Luca, A., Lynch, G.S., Grounds, M.D.

“…Duchenne muscular dystrophy is a lethal X-linked muscle disease resulting from a defect in the muscle membrane protein dystrophin. The absence of dystrophin…”
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