Search Results - "Lynch, Jeffrey"

A Thrombospondin-Dependent Pathway for a Protective ER Stress Response by Lynch, Jeffrey M., Maillet, Marjorie, Vanhoutte, Davy, Schloemer, Aryn, Sargent, Michelle A., Blair, N. Scott, Lynch, Kaari A., Okada, Tetsuya, Aronow, Bruce J., Osinska, Hanna, Prywes, Ron, Lorenz, John N., Mori, Kazutoshi, Lawler, Jack, Robbins, Jeffrey, Molkentin, Jeffery D.

“…Thrombospondin (Thbs) proteins are induced in sites of tissue damage or active remodeling. The endoplasmic reticulum (ER) stress response is also prominently…”
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In response to Green and Daniel regarding: “Malpractice against shoulder surgeons: what the data say” by Austin, Luke S., Lynch, Jeffrey C.

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Amount of CMS Reduction in Facility Reimbursement Following Removal of Total Hip Arthroplasty From the Inpatient-Only List Far Exceeds Reduction in Actual Care Cost by Lynch, Jeffrey C., Yayac, Michael, Krueger, Chad A., Courtney, P. Maxwell

“…Starting in 2020, Centers for Medicare and Medicaid Services (CMS) removed total hip arthroplasty (THA) from the inpatient-only list, resulting in an average…”
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Return to driving following anatomic and reverse shoulder arthroplasty: a comparative analysis by DeBernardis, Dennis A., Lynch, Jeffrey C., Radack, Tyler, Austin, Luke S.

“…The currently recommended time to return to driving following shoulder arthroplasty is controversial. The purpose of this study was to determine…”
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Risk of Noise-Induced Hearing Loss for Orthopaedic Surgeons by Kwan, Stephanie A., Lynch, Jeffrey C., DeFrance, Michael, Ciesielka, Kerri-Anne, Rivlin, Michael, Daniel, Joseph N.

“…Noise-induced hearing loss (NIHL) affects the ability of an individual to communicate and can negatively impact quality of life. The risk to orthopaedic…”
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Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle by Lynch, Jeffrey M, Dolman, Andrew J, Guo, Chenying, Dolan, Katie, Xiang, Chuanxi, Reda, Samir, Li, Bing, Prasanna, Ganesh

“…Myocilin (MYOC) is the gene with mutations most common in glaucoma. In the eye, MYOC is in trabecular meshwork, ciliary body, and retina. Other tissues with…”
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Malpractice against shoulder surgeons: what the data say by Lynch, Jeffrey C., Radack, Tyler M., Stenson, James F., Riebesell, Samantha A., Austin, Luke S.

“…BACKGROUNDThousands of orthopedic surgeons in the United State face medical malpractice claims annually; however, little is known regarding the common causes…”
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Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart by Correll, Robert N., Grimes, Kelly M., Prasad, Vikram, Lynch, Jeffrey M., Khalil, Hadi, Molkentin, Jeffery D.

“…Hemodynamic stress on the mammalian heart results in compensatory hypertrophy and activation of the unfolded protein response through activating transcription…”
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Biomechanical comparison of elbow stability constructs by Stenson, James F., Lynch, Jeffrey C., Cheesman, Quincy T., DeBernardis, Dennis, Kachooei, Amir, Austin, Luke S., Rivlin, Michael

“…Despite surgical stabilization of complex elbow trauma, additional fixation to maintain joint congruity and stability may be required. Multiple biomechanical…”
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Surprise Billing in Elective Shoulder Surgery and Its Effect on Patient Satisfaction by McCahon, Joseph A S, Lynch, Jeffrey C, Radack, Tyler, Austin, Luke S

“…Patients often receive multiple bills following surgery, which may come as a surprise to them if they are not appropriately informed or educated prior to…”
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Clinical Outcomes After Ulnar Collateral Ligament Reconstructions With Concomitant Ulnar Nerve Transposition in Overhead Athletes: A Matched Cohort Analysis by Lynch, Jeffrey C., Johnson, Emma E., Ciccotti, Michael C., Erickson, Brandon J., Dodson, Christopher C., Cohen, Steven B., Ciccotti, Michael G.

“…Background: Injury of the ulnar collateral ligament (UCL) has become increasingly common, particularly in overhead athletes. There is no consensus on…”
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Next‐generation osteometric sorting: Using 3D shape, elliptical Fourier analysis, and Hausdorff distance to optimize osteological pair‐matching by Fancourt, Hayley S. M., Lynch, Jeffrey J., Byrd, John E., Stephan, Carl N.

“…Determining which bilateral bones belong to the same person based on shape and size similarity is called pair‐matching and it is instrumental for sorting…”
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Cdc42 is an antihypertrophic molecular switch in the mouse heart by Maillet, Marjorie, Lynch, Jeffrey M, Sanna, Bastiano, York, Allen J, Zheng, Yi, Molkentin, Jeffery D

“…To improve contractile function, the myocardium undergoes hypertrophic growth without myocyte proliferation in response to both pathologic and physiologic…”
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Mitsugumin 29 regulates t-tubule architecture in the failing heart by Correll, Robert N., Lynch, Jeffrey M., Schips, Tobias G., Prasad, Vikram, York, Allen J., Sargent, Michelle A., Brochet, Didier X. P., Ma, Jianjie, Molkentin, Jeffery D.

“…Transverse tubules (t-tubules) are uniquely-adapted membrane invaginations in cardiac myocytes that facilitate the synchronous release of Ca 2+ from internal…”
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Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells by Lynch, Jeffrey M., Li, Bing, Katoli, Parvaneh, Xiang, Chuanxi, Leehy, Barrett, Rangaswamy, Nalini, Saenz-Vash, Veronica, Wang, Y. Karen, Lei, Hong, Nicholson, Thomas B., Meredith, Erik, Rice, Dennis S., Prasanna, Ganesh, Chen, Amy

“…Myocilin (MYOC) was discovered more than 20 years ago and is the gene whose mutations are most commonly observed in individuals with glaucoma. Despite…”
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Full-length myocilin protein is purified from mammalian cells as a dimer by Katoli, Parvaneh, Godbole, Adarsh, Romanowski, Michael J., Clark, Kirk, Meredith, Erik, Saenz-Vash, Veronica, Wang, Y. Karen, Lewicki, Nancy, Nguyen, Andrew A., Lynch, Jeffrey M.

“…Myocilin (MYOC) is a secreted protein found in human aqueous humor (AH) and mutations in the MYOC gene are the most common mutation observed in glaucoma…”
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The Multiple Bottle Effect Is Overridden in Male and Female Rats by Simultaneous Presentation of Two Oral Nicotine Solutions by Halder, Swapnali, Lynch, Jeffrey M., Pearce, Amy R.

“…Background: Studies on the oral route of nicotine administration in rodents make important contributions to our understanding of human nicotine use, and…”
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Helicobacter pylori Disrupts NADPH Oxidase Targeting in Human Neutrophils to Induce Extracellular Superoxide Release by Allen, Lee-Ann H, Beecher, Benjamin R, Lynch, Jeffrey T, Rohner, Olga V, Wittine, Lara M

“…Helicobacter pylori (Hp) infection triggers a chronic influx of polymorphonuclear leukocyte neutrophils (PMNs) into the gastric mucosa. Although Hp reside in a…”
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FRET Analysis of in Vivo Dimerization by RNA-editing Enzymes by Chilibeck, Kaari A., Wu, Tao, Liang, Chao, Schellenberg, Matthew J., Gesner, Emily M., Lynch, Jeffrey M., MacMillan, Andrew M.

“…Members of the ADAR (adenosine deaminase that acts on RNA) enzyme family catalyze the hydrolytic deamination of adenosine to inosine within double-stranded…”
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Unusual anatomic variant of the axillary nerve challenging the deltopectoral approach to the shoulder: a case report by Pizzo, Richard A, Lynch, Jeffrey, Adams, Donald M, Yoon, Richard S, Liporace, Frank A

“…The deltopectoral approach is a well-described surgical approach to the proximal humerus and glenohumeral joint. One of the structures at risk during this…”
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