Search Results - "Lynch, J. L."

Manganese acquisition is essential for virulence of Enterococcus faecalis by Colomer-Winter, Cristina, Flores-Mireles, Ana L, Baker, Shannon P, Frank, Kristi L, Lynch, Aaron J L, Hultgren, Scott J, Kitten, Todd, Lemos, José A

“…Manganese (Mn) is an essential micronutrient that is not readily available to pathogens during infection due to an active host defense mechanism known as…”
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High-resolution imaging reveals microbial biofilms on patient urinary catheters despite antibiotic administration by Walker, Jennifer N., Flores-Mireles, Ana L., Lynch, Aaron J. L., Pinkner, Chloe, Caparon, Michael G., Hultgren, Scott J., Desai, Alana

“…Purpose Catheter-associated urinary tract infections (CAUTIs) are a significant cause of morbidity worldwide, as they account for 40% of all…”
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The Widely Used Antimicrobial Triclosan Induces High Levels of Antibiotic Tolerance In Vitro and Reduces Antibiotic Efficacy up to 100-Fold In Vivo by Westfall, Corey, Flores-Mireles, Ana Lidia, Robinson, John Isaac, Lynch, Aaron J L, Hultgren, Scott, Henderson, Jeffrey P, Levin, Petra Anne

“…The antimicrobial triclosan is used in a wide range of consumer products ranging from toothpaste, cleansers, socks, and baby toys. A bacteriostatic inhibitor…”
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Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation by Klein, Roger D, Shu, Qin, Cusumano, Zachary T, Nagamatsu, Kanna, Gualberto, Nathaniel C, Lynch, Aaron J L, Wu, Chao, Wang, Wenjie, Jain, Neha, Pinkner, Jerome S, Amarasinghe, Gaya K, Hultgren, Scott J, Frieden, Carl, Chapman, Matthew R

“…Curli amyloid fibers are produced as part of the extracellular biofilm matrix and are composed primarily of the major structural subunit CsgA. The CsgE…”
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Localization of a major susceptibility locus influencing preterm birth by Chittoor, G, Farook, V S, Puppala, S, Fowler, S P, Schneider, J, Dyer, T D, Cole, S A, Lynch, J L, Curran, J E, Almasy, L, Maccluer, J W, Comuzzie, A G, Hale, D E, Ramamurthy, R S, Dudley, D J, Moses, E K, Arya, R, Lehman, D M, Jenkinson, C P, Bradshaw, B S, Defronzo, R A, Blangero, J, Duggirala, R

“…Preterm birth (PTB) is a complex trait, but little is known regarding its major genetic determinants. The objective of this study is to localize genes that…”
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Patterns of angiotensin-converting enzyme inhibitor use in congestive heart failure in two community hospitals by Philbin, Edward F., Andreou, Costa, Rocco, Thomas A., Lynch, Laura J., Baker, Sharon L.

“…Because they provide relief of symptoms and reduce mortality, angiotensin-converting enzyme (ACE) inhibitors have become a highly recommended part of the…”
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Metabolites as novel biomarkers for childhood obesity-related traits in Mexican-American children by Farook, V. S., Reddivari, L., Chittoor, G., Puppala, S., Arya, R., Fowler, S. P., Hunt, K. J., Curran, J. E., Comuzzie, A. G., Lehman, D. M., Jenkinson, C. P., Lynch, J. L., DeFronzo, R. A., Blangero, J., Hale, D. E., Duggirala, R., Vanamala, J.

“…Summary Background/Objectives Although newer approaches have identified several metabolites associated with obesity, there is paucity of such information in…”
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Predictors and determinants of hospital length of stay in congestive heart failure in ten community hospitals by Philbin, E F, Rocco, Jr, T A, Lynch, L J, Rogers, V A, Jenkins, P

“…Little is known about the actual determinants of hospital length of stay (LOS) among patients admitted with congestive heart failure (CHF), in spite of its…”
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Pharmacology of AMG 181, a human anti‐α4β7 antibody that specifically alters trafficking of gut‐homing T cells by Pan, WJ, Hsu, H, Rees, WA, Lear, SP, Lee, F, Foltz, IN, Rathanaswami, P, Manchulenko, K, Chan, BM, Zhang, M, Xia, XZ, Patel, SK, Prince, PJ, Doherty, DR, Sheckler, CM, Reynhardt, KO, Krill, CD, Harder, BJ, Wisler, JA, Brandvig, JL, Lynch, JL, Anderson, AA, Wienkers, LC, Borie, DC

“…Background and Purpose AMG 181 is a human anti‐α4β7 antibody currently in phase 1 and 2 trials in subjects with inflammatory bowel diseases. AMG 181…”
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Nitric Oxide Activity and Isoenzyme Expression in the Senescence-Accelerated Mouse P8 Model of Alzheimer's Disease: Effects of Anti-Amyloid Antibody and Antisense Treatments by Ali, Abbas K., Banks, William A., Kumar, Vijaya B., Shah, Gul N., Lynch, Jessica L., Farr, Susan A., Fleegal-DeMotta, Melissa A., Morley, John E.

“…Amyloid beta protein (Aβ) in Alzheimer’s disease induces oxidative stress through several mechanisms, including stimulation of nitric oxide synthase (NOS)…”
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Deposition of Host Matrix Proteins on Breast Implant Surfaces Facilitates Staphylococcus Epidermidis Biofilm Formation: In Vitro Analysis by Walker, Jennifer N, Pinkner, Chloe L, Lynch, Aaron J L, Ortbal, Sarah, Pinkner, Jerome S, Hultgren, Scott J, Myckatyn, Terence M

“…Abstract Background Staphylococcus epidermidis is a primary cause of breast implant-associated infection. S epidermidis possesses several virulence factors…”
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The effect of stock option repricing on employee turnover by Carter, Mary Ellen, Lynch, Luann J.

“…We examine whether repricing underwater stock options reduces executive and overall employee turnover using a sample of firms that reprice stock options in…”
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Radiographic resolution of lymphocytic interstitial pneumonitis (LIP) in children with human immunodeficiency virus (HIV): not a sign of clinical deterioration by LYNCH, Jennifer L, BLICKMAN, Johan G, TERMEULEN, Deborah C, BABL, Franz E, MOLONEY, Carole H, PELTON, Stephen I

“…The literature and anecdotal evidence associate the resolution of radiographic findings of lymphocytic interstitial pneumonitis (LIP) with a decline in immune…”
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The consequences of the FASB's 1998 proposal on accounting for stock option repricing by Carter, Mary Ellen, Lynch, Luann J.

“…We examine repricing activity surrounding the FASB's 1998 announcement regarding accounting for repriced options. We find that repricing increases during, and…”
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The relationship between hospital length of stay and rate of death in heart failure by Philbin, Edward F., Rogers, Vicki A., Sheesley, Karen A., Lynch, Laura J., Andreou, Costa, Rocco, Thomas A.

“…OBJECTIVE: To study the relationship between length of stay (LOS) and the rate of death among patients hospitalized with congestive heart failure (CHF)…”
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General practice by Lynch, L J, Hamilton, L

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Liraglutide in Children and Adolescents with Type 2 Diabetes by Tamborlane, William V, Barrientos-Pérez, Margarita, Fainberg, Udi, Frimer-Larsen, Helle, Hafez, Mona, Hale, Paula M, Jalaludin, Muhammad Y, Kovarenko, Margarita, Libman, Ingrid, Lynch, Jane L, Rao, Paturi, Shehadeh, Naim, Turan, Serap, Weghuber, Daniel, Barrett, Timothy

“…This trial assessed the efficacy and safety of liraglutide as compared with placebo, added to metformin (with or without basal insulin treatment), in children…”
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Opiate modulation of IL-1α, IL-2, and TNF-α transport across the blood–brain barrier by Lynch, Jessica L, Banks, William A

“…Abstract Interleukin-1α (IL-1α), interleukin-2 (IL-2), and tumor necrosis factor α (TNF-α) are proinflammatory cytokines with potent neuromodulatory effects…”
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Does QI work? The Management to Improve Survival in Congestive Heart Failure (MISCHF) study by Philbin, E F, Lynch, L J, Rocco, T A, Lindenmuth, N W, Ulrich, K, McCall, M, Jenkins, P, Roerden, J B

“…In an ongoing study, a randomized, controlled trial is being conducted on the effects of a collaborative quality improvement program on practice patterns and…”
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Effect of hemorrhagic shock on transmembrane potential by Campion, D S, Lynch, L J, Rector, Jr, F C, Carter, N, Shires, G T

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