Search Results - "Lynch, Donna"

Interleukin‐6: A novel biomarker for monoclonal antibody and chemotherapy‐associated hypersensitivity confirms a cytokine release syndrome phenotype‐endotype association by Jakubovic, Baruch D., Sanchez‐Sanchez, Soledad, Hamadi, Sahar, Lynch, Donna‐Marie, Castells, Mariana

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Hypersensitivity reactions to therapeutic monoclonal antibodies: Phenotypes and endotypes by Isabwe, Ghislaine Annie C., Garcia Neuer, Marlene, de las Vecillas Sanchez, Leticia, Lynch, Donna-Marie, Marquis, Kathleen, Castells, Mariana

“…The increasing use of mAbs has led to a rise in hypersensitivity reactions (HSRs), which prevent their use as first-line therapy. HSRs' symptoms, diagnostic…”
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Anaphylaxis and systemic mastocytosis controlled with KIT inhibitors in a patient with metastatic lung adenocarcinoma by Hernandez, Camellia L., Lynch, Donna‐Marie, Golash, Abby Jane, Marquis, Kathleen, Besz, Kylie Marie, Oxnard, Geoffrey, Rotow, Julia, DeAngelo, Daniel J., Castells, Mariana

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Differential presentation of hypersensitivity reactions to carboplatin and oxaliplatin: Phenotypes, endotypes, and management with desensitization by Jimenez‐Rodriguez, Teodorikez‐Wilfox, de las Vecillas, Leticia, Labella, Marina, Lynch, Donna‐Marie, Besz, Kylie Marie, Marquis, Kathleen, Burgos, Amparo, Soriano Gomis, Victor, Lozano, Inmaculada, Antón, Rosa Ana Montoyo, Calle, Francisco Marco, González Delgado, María Purificación, Gutiérrez, Aurora, Montenegro, Estefanía, Rodríguez, Fernando, Fernández Sánchez, Francisco Javier, Castells, Mariana

“…Background Drug hypersensitivity reactions (DHRs) to platinum‐based drugs are heterogenous and restrict their access, and drug desensitization (DD) has…”
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Endophenotyping Oxaliplatin Hypersensitivity: Personalizing Desensitization to the Atypical Platin by Silver, Jared, Garcia-Neuer, Marlene, Lynch, Donna-Marie, Pasaoglu, Gülden, Sloane, David E., Castells, Marianna

“…Oxaliplatin causes a wider variety of immediate hypersensitivity reactions than do other platin-based chemotherapeutics. Some resemble type 1 reactions that…”
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A Three-Step Taxane Titration Protocol Decreases Hypersensitivity Reactions During First and Second Exposures by Lynch, Donna-Marie, Menon, Susanne, Mazzola, Emanuele, Costa, Jennifer, Jabaley, Terri

“…Patients receiving taxanes are at risk for developing hypersensitivity reactions (HSRs) primarily during first and second lifetime exposures. Immediate HSRs…”
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Development of a Pipeline for Removing Allergy Labels in Patients Undergoing Hematopoietic Stem Cell Transplantation by Merz, Lauren E., Huang, George X., Mehta, Geneva D., Lynch, Donna-Marie, Maliborski, Natalia, Besz, Kylie, Wickner, Paige, Cutler, Corey, Castells, Mariana

“…•A pipeline was developed to assess HSCT recipients with penicillin allergy labels.•Barriers to pipeline implementation were addressed through multiple PDSA…”
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Phenotypes of hypersensitivity reactions to pegylated liposomal doxorubicin: Safety and efficacy of 128 rapid desensitizations by Tuttle, Katherine L., Lynch, Donna-Marie, Marquis, Kathleen, Besz, Kylie Marie, Matulonis, Ursula A., Castells, Mariana C.

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Successful administration of omalizumab by desensitization protocol following systemic reactions in 12 patients by Bernaola, Marta, Hamadi, Sahar A., Lynch, Donna-Marie, Marquis, Kathleen A., Silver, Jared N., Castells, Mariana C., Hsu, Joyce T.

“…Omalizumab is a recombinant IgG monoclonal antibody that inhibits binding to the high-affinity IgE receptor, currently approved by the US Food and Drug…”
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Progestogen Hypersensitivity in 24 Cases: Diagnosis, Management, and Proposed Renaming and Classification by Foer, Dinah, MD, Buchheit, Kathleen M., MD, Gargiulo, Antonio Rosario, MD, Lynch, Donna Marie, BSN, RN, Castells, Mariana, MD, PhD, Wickner, Paige G., MD, MPH

“…Background Autoimmune progesterone dermatitis is a poorly recognized syndrome associated with a hypersensitivity to progestogens. Symptoms present…”
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Update on Desensitization by Campos, Lucila, Hamadi, Sahar A., Lynch, Donna-Marie, Marquis, Kathleen, Castells, Mariana C.

“…Purpose of review Rapid drug desensitization (RDD) is a high-risk protocol that allows patients with hypersensitivity reactions to remain on first-line therapy…”
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Intravenous Iron Hypersensitivity Evaluation and Desensitization by Hsu, Joyce T., MD, Chan, Grace Y., MD, Lynch, Donna-Marie, NP, Castells, Mariana C., MD, PhD, FAAAAI

“…Methods Patients with a history of iron hypersensitivity were evaluated in the Brigham and Women's Hospital Allergy Clinic…”
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Melphalan desensitization following immediate hypersensitivity in a patient undergoing conditioning for autologous hematopoietic cell transplantation by Ganetsky, Alex, PharmD, Takach, Patricia A., MD, Lynch, Donna-Marie, NP, Krause, Tracy M., PharmD, Teh, Jian S., MD, Stadtmauer, Edward A., MD, Castells, Mariana, MD, PhD, Weiss, Brendan M., MD

“…Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a paraneoplastic disorder associated with an…”
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Integrating DSM-IV Factors to Predict Violence in High-Risk Psychiatric Patients by Lynch, Donna M., Noel, Helen C.

“…:  This study incorporated Axis‐II and Axis‐IV factors in DSM‐IV to test the relationship between predicted risk for violence assessed in the psychiatric…”
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Basophil Activation Test as a Biomarker for Taxanes Anaphylaxis by De Campos, Lucila, Giavina-Bianchi, Pedro, Acharya, Shree, Lynch, Donna-Marie, Kalil, Jorge, Castells, Mariana C.

“…Introduction Taxanes are widely used chemotherapy agents, and their administration, despite premedication, is associated with hypersensitivity reactions (HR)…”
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STANDARDIZED GUIDELINES IN RESUMING TAXANE INFUSIONS AFTER A HYPERSENSITIVITY REACTION by Lynch, Donna-Marie

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Screening for drug-dependent antibodies to prevent complications in patients receiving oxaliplatin desensitization by Huang, George, Lynch, Donna, Castells, Mariana

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Resource utilisation and time commitment associated with correction of anaemia in cancer patients using epoetin alfa by Lynch, Donna-Marie, Slaven, Tracey

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The good behaviour game: Maintenance effects by Lynch, Donna, Keenan, Mickey

“…•The Good Behaviour Game reduced disruptive behaviours of children in a classroom.•Positive comments from teachers for increases in good behaviour was…”
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Mast cell activation syndrome by Vacheron, Nathalie, McClinton, Tracy, Lynch-Smith, Donna J., Umberger, Reba

“…Mast cell activation syndrome (MCAS) is a systemic autoinflammatory disease in which mast cells behave erratically. It is unknown whether MCAS recently evolved…”
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