Search Results - "Lynch, Aileen"

Internet Use by Parents of Children With Rare Conditions: Findings From a Study on Parents' Web Information Needs by Nicholl, Honor, Tracey, Catherine, Begley, Thelma, King, Carole, Lynch, Aileen M

“…Parents of children with rare conditions increasingly use the Internet to source information on their child's condition. This study reports on part of a larger…”
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Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activation in vivo and in vitro by Lyons, Anthony, Lynch, Aileen M, Downer, Eric J, Hanley, Riona, O'Sullivan, Joan B, Smith, Andrew, Lynch, Marina A

“…Several neurodegenerative disorders are associated with evidence of inflammation, one feature of which is increased activation of microglia, the most likely…”
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Antidepressant-associated sexual dysfunction: impact, effects, and treatment by Higgins, Agnes, Nash, Michael, Lynch, Aileen M

“…Sexual dysfunction is a common side effect of antidepressants and can have significant impact on the person's quality of life, relationships, mental health,…”
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Active older adults goal setting outcomes for engaging in a physical activity app and the motivation characteristics of these goals (MOVEAGE-ACT) by Lynch, Aileen M., Kilroy, Sean, McKee, Heather, Sheerin, Fintan, Epstein, Monique, Girault, Ariane, Gillois, Pierre, Bosson, Jean Luc, Rolland, Carole, Harkin, Mary, McKinney, Ciarán, McKee, Gabrielle

“…•Goal setting outcomes were physical, functional, mental, disease and age-related deterioration.•Motivation was autonomous and internal and more likely to lead…”
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Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain by Loane, David J, Deighan, Brian F, Clarke, Rachael M, Griffin, Rebecca J, Lynch, Aileen M, Lynch, Marina A

“…Abstract Increased expression of proinflammatory cytokines, like interleukin-1β (IL-1β), is a feature of the aged brain and it is generally accepted that the…”
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Eicosapentaenoic acid confers neuroprotection in the amyloid-β challenged aged hippocampus by Lynch, Aileen M, Loane, David J, Minogue, Aedín M, Clarke, Rachael M, Kilroy, Dana, Nally, Rachel E, Roche, Óran J, O’Connell, Florence, Lynch, Marina A

“…Abstract Among the changes that occur in the hippocampus with age, is a deficit in long-term potentiation (LTP). This impairment is associated with…”
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Modulation of amyloid-β-induced and age-associated changes in rat hippocampus by eicosapentaenoic acid by Minogue, Aedín M, Lynch, Aileen M, Loane, David J, Herron, Caroline E, Lynch, Marina A

“…The age-related deficit in long-term potentiation (LTP) in the dentate gyrus is positively correlated with hippocampal concentration of the pro-inflammatory…”
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The impact of glial activation in the aging brain by Lynch, Aileen M, Murphy, Kevin J, Deighan, Brian F, O'Reilly, Julie-Ann, Gun'ko, Yuri K, Cowley, Thelma R, Gonzalez-Reyes, Rodrigo E, Lynch, Marina A

“…The past decade or so has witnessed a rekindling of interest in glia requiring a re-evaluation of the early descriptions of astrocytes as merely support cells,…”
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Prevalence of tobacco smoking among European migrants residing in EU 15 countries: a quantitative systematic review protocol by Byrne, Gobnait, Murphy, Fiona, Eustace-Cook, Jessica, Mooney, Mary, O’Brien, Frances, O’Donnell, Sharon, Corry, Margarita, Lynch, Aileen M., Neenan, Kathleen, McKee, Gabrielle

“…The objective of this systematic review is to summarize the prevalence of tobacco smoking in European migrants residing in EU 15 countries. Most of the…”
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The age-related increase in IL-1 type I receptor in rat hippocampus is coupled with an increase in caspase-3 activation by Lynch, Aileen M., Lynch, Marina A.

“…Evidence from several studies indicates that expression of interleukin‐1β (IL‐1β) and IL‐1 type I receptor is particularly high in hippocampus, and it has…”
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Lipopolysaccharide‐induced increase in signalling in hippocampus is abrogated by IL‐10 – a role for IL‐1β? by Lynch, Aileen M., Walsh, Christine, Delaney, Ada, Nolan, Yvonne, Campbell, Veronica A., Lynch, Marina A.

“…Parenterally administered lipopolysaccharide (LPS) increases the concentration of the pro‐inflammatory cytokine interleukin‐1β (IL‐1β) in the rat hippocampus…”
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Evidence that lipopolysaccharide-induced cell death is mediated by accumulation of reactive oxygen species and activation of p38 in rat cortex and hippocampus by Nolan, Yvonne, Vereker, Emily, Lynch, Aileen M, Lynch, Marina A

“…Lipopolysaccharide (LPS) administration stimulates immune activation, inflammation and deterioration in cell function. Neuronal tissue in cortex and…”
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Analysis of interleukin-1 beta-induced cell signaling activation in rat hippocampus following exposure to gamma irradiation. Protective effect of eicosapentaenoic acid by Lynch, Aileen M, Moore, Michelle, Craig, Sarah, Lonergan, Peter E, Martin, Darren S, Lynch, Marina A

“…Among the many reported effects of irradiation in cells is activation of the stress-activated protein kinase, c-Jun N-terminal kinase (JNK), which has been…”
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157Role of Cardio-metabolic Risk Factors in the Relationship Between Physical Activity and Cardiovascular Disease: the Irish Longitudinal Study on Ageing TILDA by Kilroy, Sean, McKee, Gabrielle, Lynch, Aileen

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157; Role of Cardio-metabolic Risk Factors in the Relationship Between Physical Activity and Cardiovascular Disease: the Irish Longitudinal Study on Ageing TILDA by Kilroy, Sean, McKee, Gabrielle, Lynch, Aileen

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173 A Qualitative Study Exploring Facilitators and Barriers to Engagement in Physical Activity Among Older Irish and French Adults by Sheerin, Fintan, Lynch, Aileen, Kilroy, Sean, Epstein, Monique, Girault, Ariane, Larose, Inès, Gillois, Pierre, Rolland, Carole, McKinney, Ciarán, Harkin, Mary, McKee, Gabrielle

“…Abstract Background The physical and mental health benefits of physical activity (PA) in older adults have been well-documented. However, a large proportion of…”
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P1‐317: Role of GAP‐43 in axonal damage and regeneration in neuroinflammatory situations by Ayasolla, Kameshwar R., Lynch, Aileen

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Role of GAP-43 in axonal damage and regeneration in neuroinflammatory situations by Ayasolla, Kameshwar R, Lynch, Aileen

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The anti-inflammatory cytokine, interleukin (IL)-10, blocks the inhibitory effect of IL-1 beta on long term potentiation. A role for JNK by Kelly, A, Lynch, A, Vereker, E, Nolan, Y, Queenan, P, Whittaker, E, O'Neill, L A, Lynch, M A

“…Several effects of the proinflammatory cytokine, interleukin-1 beta (IL-1 beta), have been described in the central nervous system, and one area of the brain…”
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Activation of c‐Jun‐N‐terminal kinase is critical in mediating lipopolysaccharide‐induced changes in the rat hippocampus by Barry, Claire E., Nolan, Yvonne, Clarke, Rachael M., Lynch, Aileen, Lynch, Marina A.

“…Lipopolysaccharide (LPS) exerts a myriad of effects in rat hippocampus; it increases the concentration of the proinflammatory cytokine, interleukin‐1β (IL‐1β),…”
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