Search Results - "Lynch, Aaron J. L."

Manganese acquisition is essential for virulence of Enterococcus faecalis by Colomer-Winter, Cristina, Flores-Mireles, Ana L, Baker, Shannon P, Frank, Kristi L, Lynch, Aaron J L, Hultgren, Scott J, Kitten, Todd, Lemos, José A

“…Manganese (Mn) is an essential micronutrient that is not readily available to pathogens during infection due to an active host defense mechanism known as…”
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High-resolution imaging reveals microbial biofilms on patient urinary catheters despite antibiotic administration by Walker, Jennifer N., Flores-Mireles, Ana L., Lynch, Aaron J. L., Pinkner, Chloe, Caparon, Michael G., Hultgren, Scott J., Desai, Alana

“…Purpose Catheter-associated urinary tract infections (CAUTIs) are a significant cause of morbidity worldwide, as they account for 40% of all…”
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The Widely Used Antimicrobial Triclosan Induces High Levels of Antibiotic Tolerance In Vitro and Reduces Antibiotic Efficacy up to 100-Fold In Vivo by Westfall, Corey, Flores-Mireles, Ana Lidia, Robinson, John Isaac, Lynch, Aaron J L, Hultgren, Scott, Henderson, Jeffrey P, Levin, Petra Anne

“…The antimicrobial triclosan is used in a wide range of consumer products ranging from toothpaste, cleansers, socks, and baby toys. A bacteriostatic inhibitor…”
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Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation by Klein, Roger D, Shu, Qin, Cusumano, Zachary T, Nagamatsu, Kanna, Gualberto, Nathaniel C, Lynch, Aaron J L, Wu, Chao, Wang, Wenjie, Jain, Neha, Pinkner, Jerome S, Amarasinghe, Gaya K, Hultgren, Scott J, Frieden, Carl, Chapman, Matthew R

“…Curli amyloid fibers are produced as part of the extracellular biofilm matrix and are composed primarily of the major structural subunit CsgA. The CsgE…”
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Deposition of Host Matrix Proteins on Breast Implant Surfaces Facilitates Staphylococcus Epidermidis Biofilm Formation: In Vitro Analysis by Walker, Jennifer N, Pinkner, Chloe L, Lynch, Aaron J L, Ortbal, Sarah, Pinkner, Jerome S, Hultgren, Scott J, Myckatyn, Terence M

“…Abstract Background Staphylococcus epidermidis is a primary cause of breast implant-associated infection. S epidermidis possesses several virulence factors…”
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