Search Results - "Lyle, Karen S"

Reactions of the Diiron Enzyme Stearoyl-Acyl Carrier Protein Desaturase by Fox, Brian G, Lyle, Karen S, Rogge, Corina E

“…Stearoyl-acyl carrier protein Δ9 desaturase (Δ9D) produces oleic acid, a nutritionally valuable fatty acid containing a cis double bond between C-9 and C-10…”
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cAMP-induced Epac-Rap activation inhibits epithelial cell migration by modulating focal adhesion and leading edge dynamics by Lyle, Karen S., Raaijmakers, Judith H., Bruinsma, Wytse, Bos, Johannes L., de Rooij, Johan

“…Epithelial cell migration is a complex process crucial for embryonic development, wound healing and tumor metastasis. It depends on alterations in cell–cell…”
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GSK3β phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment by Kumar, Praveen, Lyle, Karen S, Gierke, Sarah, Matov, Alexandre, Danuser, Gaudenz, Wittmann, Torsten

“…Polarity of the microtubule (MT) cytoskeleton is essential for many cell functions. Cytoplasmic linker-associated proteins (CLASPs) are MT-associated proteins…”
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X‐ray structure of putative acyl‐ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv by Dyer, David H., Lyle, Karen S., Rayment, Ivan, Fox, Brian G.

“…Genome sequencing showed that two proteins in Mycobacterium tuberculosis H37Rv contain the metal binding motif (D/E)X2HX∼100(D/E)X2H characteristic of the…”
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Rapid-Mix and Chemical Quench Studies of Ferredoxin-Reduced Stearoyl-Acyl Carrier Protein Desaturase by Lyle, Karen S, Haas, Jeffrey A, Fox, Brian G

“…Stearoyl-ACP Δ9 desaturase (Δ9D) catalyzes the NADPH- and O2-dependent insertion of a cis double bond between the C9 and C10 positions of stearoyl-ACP…”
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Microtubule dynamics regulation contributes to endothelial morphogenesis by Lyle, Karen S, Corleto, Jose A, Wittmann, Torsten

“…Because little is known how microtubules contribute to cell migration in a physiological three-dimensional environment, we analyzed microtubule function and…”
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Identification of the Binding Region of the [2Fe-2S] Ferredoxin in Stearoyl-Acyl Carrier Protein Desaturase:  Insight into the Catalytic Complex and Mechanism of Action by Sobrado, Pablo, Lyle, Karen S, Kaul, Steven P, Turco, Michelle M, Arabshahi, Ida, Marwah, Ashok, Fox, Brian G

“…Stearoyl-acyl carrier protein desaturase (Δ9D) catalyzes the O2 and 2e- dependent desaturation of stearoyl-acyl carrier protein (18:0-ACP) to yield oleoyl-ACP…”
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Resonance Raman Studies of the Stoichiometric Catalytic Turnover of a Substrate−Stearoyl-Acyl Carrier Protein Δ9 Desaturase Complex by Lyle, Karen S, Möenne-Loccoz, Pierre, Ai, Jingyuan, Sanders-Loehr, Joann, Loehr, Thomas M, Fox, Brian G

“…Resonance Raman spectroscopy has been used to study the effects of substrate binding (stearoyl-acyl carrier protein, 18:0-ACP) on the diferric centers of…”
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GSK3[beta] phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment by Kumar, Praveen, Lyle, Karen S, Gierke, Sarah, Matov, Alexandre, Danuser, Gaudenz, Wittmann, Torsten

“…Polarity of the microtubule (MT) cytoskeleton is essential for many cell functions. Cytoplasmic linker-associated proteins (CLASPs) are MT-associated proteins…”
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GSK3beta phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment by Kumar, Praveen, Lyle, Karen S, Gierke, Sarah, Matov, Alexandre, Danuser, Gaudenz, Wittmann, Torsten

“…Polarity of the microtubule (MT) cytoskeleton is essential for many cell functions. Cytoplasmic linker-associated proteins (CLASPs) are MT-associated proteins…”
Get full text

Resonance Raman Studies of the Stoichiometric Catalytic Turnover of a Substrate−Stearoyl-Acyl Carrier Protein Δ 9 Desaturase Complex by Lyle, Karen S., Möenne-Loccoz, Pierre, Ai, Jingyuan, Sanders-Loehr, Joann, Loehr, Thomas M., Fox, Brian G.

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Mechanism and function of soluble acyl -acyl carrier protein desaturase systems in fatty acid metabolism by Lyle, Karen S

“…Stearoyl acyl carrier protein Δ9 desaturase (Δ9D) catalyzes the O2− and NADPH-dependent insertion of a cis double bond between carbons 9 and 10 of…”
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