Search Results - "Lyke, K E"

Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8⁺ T Cell Immunity by Epstein, J. E., Tewari, K., Lyke, K. E., Sim, B. K. L., Billingsley, P. F., Laurens, M. B., Gunasekera, A., Chakravarty, S., James, E. R., Sedegah, M., Richman, A., Velmurugan, S., Reyes, S., Li, M., Tucker, K., Ahumada, A., Ruben, A. J., Li, T., Stafford, R., Eappen, A. G., Tamminga, C., Bennett, J. W., Ockenhouse, C. F., Murphy, J. R., Komisar, J., Thomas, N., Loyevsky, M., Birkett, A., Plowe, C. V., Loucq, C., Edelman, R., Richie, T. L., Seder, R. A., Hoffman, S. L.

“…Our goal is to develop a vaccine that sustainably prevents Plasmodium falciparum (Pf) malaria in ≥80% of recipients. Pf sporozoites (PfSPZ) administered by…”
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Serum Levels of the Proinflammatory Cytokines Interleukin-1 Beta (IL-1β), IL-6, IL-8, IL-10, Tumor Necrosis Factor Alpha, and IL-12(p70) in Malian Children with Severe Plasmodium falciparum Malaria and Matched Uncomplicated Malaria or Healthy Controls by LYKE, K. E, BURGES, R, SZTEIN, M. B, CISSOKO, Y, SANGARE, L, DAO, M, DIARRA, I, KONE, A, HARLEY, R, PLOWE, C. V, DOUMBO, O. K

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Ventriculitis Complicating Use of Intraventricular Catheters in Adult Neurosurgical Patients by Lyke, K. E., Obasanjo, O. O., Williams, M. A., O'Brien, M., Chotani, R., Perl, T. M.

“…Ventriculitis is a serious complication of intraventricular catheter (IVC) use, with rates of IVC-related infections ranging from 0% to 45% and gram-positive…”
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A Case of Cutaneous Ulcerative Alternariosis: Rare Association with Diabetes Mellitus and Unusual Failure of Itraconazole Treatment by Lyke, Kirsten E., Miller, Nancy S., Towne, Laura, Merz, William G.

“…Alternaria species are ubiquitous dematiaceous fungi that are increasingly recognized as pathogens in immunocompromised patients or those with significant…”
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Erythrocyte CR1 expression level does not correlate with a HindIII restriction fragment length polymorphism in Africans; implications for studies on malaria susceptibility by Rowe, J A, Raza, A, Diallo, D A, Baby, M, Poudiougo, B, Coulibaly, D, Cockburn, I A, Middleton, J, Lyke, K E, Plowe, C V, Doumbo, O K, Moulds, J M

“…Complement receptor 1 (CR1) expression level on erythrocytes is genetically determined, and in Caucasian populations is linked to high (H) and low (L)…”
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Identification of the Kna/Knb polymorphism and a method for Knops genotyping by Moulds, J.M., Thomas, B.J., Doumbo, O., Diallo, D.A., Lyke, K.E., Plowe, C.V., Rowe, J.A., Birmingham, D.J.

“…BACKGROUND: DNA mutations resulting in the McCoy and Swain‐Langley polymorphisms have been identified on complement receptor 1 (CR1)—a ligand for rosetting of…”
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Association of HLA alleles with Plasmodium falciparum severity in Malian children by Lyke, K. E., Fernández-Viňa, M. A., Cao, K., Hollenbach, J., Coulibaly, D., Kone, A. K., Guindo, A., Burdett, L. A., Hartzman, R. J., Wahl, A. R., Hildebrand, W. H., Doumbo, O. K., Plowe, C. V., Sztein, M. B.

“…Pre‐erythrocytic immunity to Plasmodium falciparum malaria is likely to be mediated by T‐cell recognition of malaria epitopes presented on infected host cells…”
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Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci by Cao, K., Moormann, A.M., Lyke, K.E., Masaberg, C., Sumba, O.P., Doumbo, O.K., Koech, D., Lancaster, A., Nelson, M., Meyer, D., Single, R., Hartzman, R.J., Plowe, C.V., Kazura, J., Mann, D.L., Sztein, M.B., Thomson, G., Fernández-Viña, M.A.

“…:  The allelic and haplotypic diversity of the HLA‐A, HLA‐B, and HLA‐C loci was investigated in 852 subjects from five sub‐Saharan populations from Kenya…”
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High Levels of Plasmodium falciparum Rosetting in All Clinical Forms of Severe Malaria in African Children by Doumbo, Ogobara K, Thera, Mahamadou A, Kone, Abdoulaye K, Raza, Ahmed, Tempest, Louisa J, Lyke, Kirsten E, Plowe, Christopher V, Rowe, J. Alexandra

“…Plasmodium falciparum rosetting (the spontaneous binding of infected erythrocytes to uninfected erythrocytes) is a well-recognized parasite virulence factor…”
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Association of Schistosoma haematobium infection with protection against acute Plasmodium falciparum malaria in Malian children by Lyke, Kirsten E, Dicko, Alassane, Dabo, Abdoulaye, Sangare, Lansana, Kone, Abdoulaye, Coulibaly, Drissa, Guindo, Ando, Traore, Karim, Daou, Modibo, Diarra, Issa, Sztein, Marcelo B, Plowe, Christopher V, Doumbo, Ogobara K

“…Plasmodium falciparum and Schistosoma haematobium are co-endemic parasitic diseases with worldwide distribution. Evidence suggests interactions occur between…”
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Impact of Trimethoprim-Sulfamethoxazole Prophylaxis on Falciparum Malaria Infection and Disease by Thera, Mahamadou A., Sehdev, Paul S., Coulibaly, Drissa, Traore, Karim, Garba, Mamane N., Cissoko, Yacouba, Kone, Abdoulaye, Guindo, Ando, Dicko, Alassane, Beavogui, Abdoul H., Djimde, Abdoulaye A., Lyke, Kirsten E., Diallo, Dapa A., Doumbo, Ogobara K., Plowe, Christopher V.

“…BackgroundTrimethoprim-sulfamethoxazole (TS) prophylaxis is recommended for persons living with human immunodeficiency virus infection and acquired…”
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Association of intraleukocytic Plasmodium falciparum malaria pigment with disease severity, clinical manifestations, and prognosis in severe malaria by Lyke, Kirsten E, Diallo, Dapa A, Dicko, Alassane, Kone, Abdoulaye, Coulibaly, Drissa, Guindo, Ando, Cissoko, Yacouba, Sangare, Lansana, Coulibaly, Seydou, Dakouo, Blaise, Taylor, Terrie E, Doumbo, Ogobara K, Plowe, Christopher V

“…Peripheral parasite density of Plasmodium falciparum is used as an indicator of malaria disease severity, but does not quantify central sequestration, which is…”
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Low multiplication rates of African Plasmodium falciparum isolates and lack of association of multiplication rate and red blood cell selectivity with malaria virulence by Deans, Anne-Marie, Lyke, Kirsten E, Thera, Mahamadou A, Plowe, Christopher V, Koné, Abdoulaye, Doumbo, Ogobara K, Kai, Oscar, Marsh, Kevin, Mackinnon, Margaret J, Raza, Ahmed, Rowe, J Alexandra

“…Two potential malaria virulence factors, parasite multiplication rate (PMR) and red blood cell selectivity (measured as selectivity index [SI]), were assessed…”
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Platelet-mediated clumping of Plasmodium falciparum infected erythrocytes is associated with high parasitemia but not severe clinical manifestations of malaria in African children by Arman, Mònica, Raza, Ahmed, Tempest, Louisa J, Lyke, Kirsten E, Thera, Mahamadou A, Koné, Abdoulaye, Plowe, Christopher V, Doumbo, Ogobara K, Rowe, J Alexandra

“…Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is an adhesive phenotype commonly found in field isolates that has previously been…”
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Incidence of severe Plasmodium falciparum malaria as a primary endpoint for vaccine efficacy trials in Bandiagara, Mali by Lyke, Kirsten E, Dicko, Alassane, Kone, Abdoulaye, Coulibaly, Drissa, Guindo, Ando, Cissoko, Yacouba, Traoré, Karim, Plowe, Christopher V, Doumbo, Ogobara K

“…Potential endpoints for blood stage malaria vaccine efficacy trials include uncomplicated malaria disease, which is hard to differentiate from other febrile…”
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HLA-A2 Supertype-Restricted Cell-Mediated Immunity by Peripheral Blood Mononuclear Cells Derived from Malian Children with Severe or Uncomplicated Plasmodium falciparum Malaria and Healthy Controls by Lyke, Kirsten E, Burges, Robin B, Cissoko, Yacouba, Sangare, Lansana, Kone, Abdoulaye, Dao, Modibo, Diarra, Issa, Fernández-Viňa, Marcelo A, Plowe, Christopher V, Doumbo, Ogobara K, Sztein, Marcelo B

“…Understanding HLA-restricted adaptive host immunity to defined epitopes of malarial antigens may be required for the development of successful malaria…”
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Identification of the Kn super(a)-Kn super(b) polymorphism and a method for Knops genotyping by Moulds, J M, Thomas, B J, Doumbo, O, Diallo, DA, Lyke, KE, Plowe, C V, Rowe, JA, Birmingham, D J

“…BACKGROUND:DNA mutations resulting in the McCoy and Swain-Langley polymorphisms have been identified on complement receptor 1 (CR1)-a ligand for rosetting of…”
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HLA-A, -B and -Cw allele frequencies in a population from Bandigara, Mali by Cao, K., Lyke, K.E., Masaberg, C., Doumbo, O.K., Ng, J., Hartzman, R.J., Plowe, C.V., Sztein, M.B., Fernández-Viña, M.A.

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