Search Results - "Lydia Scarfò"

Novel therapies and combinations in CLL refractory to BTK inhibitors and venetoclax by Scarfò, Lydia

“…Patients with chronic lymphocytic leukemia (CLL) refractory to covalent BTK and BCL2 inhibitors have a new unmet clinical need. Standard treatment options are…”
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COVID-19 prophylaxis: half-full or half-empty glass? by Scarfò, Lydia, Cuneo, Antonio

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CLL and COVID-19: light at the end of the tunnel? by Scarfò, Lydia, Herishanu, Yair

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Reprogramming cell death: BCL2 family inhibition in hematological malignancies by Scarfò, Lydia, Ghia, Paolo

“…Abstract The BCL2 family members play a central role in regulating programmed cell death (apoptosis) and arbitrating the cellular fate through an accurate…”
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Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia by Herishanu, Yair, Avivi, Irit, Aharon, Anat, Shefer, Gabi, Levi, Shai, Bronstein, Yotam, Morales, Miguel, Ziv, Tomer, Shorer Arbel, Yamit, Scarfò, Lydia, Joffe, Erel, Perry, Chava, Ghia, Paolo

“…Patients with chronic lymphocytic leukemia (CLL) have an increased risk for severe COVID-19 disease and mortality. The goal of this study was to determine the…”
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Outcomes of patients with hematologic malignancies and COVID-19: a systematic review and meta-analysis of 3377 patients by Vijenthira, Abi, Gong, Inna Y., Fox, Thomas A., Booth, Stephen, Cook, Gordon, Fattizzo, Bruno, Martín-Moro, Fernando, Razanamahery, Jerome, Riches, John C., Zwicker, Jeff, Patell, Rushad, Vekemans, Marie Christiane, Scarfò, Lydia, Chatzikonstantinou, Thomas, Yildiz, Halil, Lattenist, Raphaël, Mantzaris, Ioannis, Wood, William A., Hicks, Lisa K.

“…Outcomes for patients with hematologic malignancy infected with COVID-19 have not been aggregated. The objective of this study was to perform a systematic…”
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Chronic lymphocytic leukaemia by Scarfò, Lydia, Ferreri, Andrés J.M, Ghia, Paolo

“…Abstract Chronic lymphocytic leukaemia (CLL) is the most common leukaemia among the adults in the Western World. CLL (and the corresponding nodal entity small…”
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The evolving treatment landscape of chronic lymphocytic leukemia by Schiattone, Luana, Ghia, Paolo, Scarfò, Lydia

“…PURPOSE OF REVIEWThis review provides guidance in the rapidly changing scenario of chronic lymphocytic leukemia (CLL) treatment. New studies as well as updates…”
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Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia by Sana, Ilenia, Mantione, Maria Elena, Meloni, Miriam, Riba, Michela, Ranghetti, Pamela, Scarfò, Lydia, Ghia, Paolo, Muzio, Marta

“…Chronic lymphocytic leukemia (CLL) co‐evolves with its own microenvironment where inflammatory stimuli including toll‐like receptors (TLR) signaling can…”
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Are we finally getting personal? Moving towards a personalized approach in chronic lymphocytic leukemia by Albi, Elisa, Capasso, Antonella, Schiattone, Luana, Ghia, Paolo, Scarfò, Lydia

“…With its heterogeneous biological features and clinical course, chronic lymphocytic leukemia (CLL), the most frequent adult leukemia in the Western world, is a…”
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Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia by Minici, Claudia, Gounari, Maria, Übelhart, Rudolf, Scarfò, Lydia, Dühren-von Minden, Marcus, Schneider, Dunja, Tasdogan, Alpaslan, Alkhatib, Alabbas, Agathangelidis, Andreas, Ntoufa, Stavroula, Chiorazzi, Nicholas, Jumaa, Hassan, Stamatopoulos, Kostas, Ghia, Paolo, Degano, Massimo

“…Cell-autonomous B-cell receptor (BcR)-mediated signalling is a hallmark feature of the neoplastic B lymphocytes in chronic lymphocytic leukaemia (CLL). Here we…”
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Exploiting B-cell Receptor Stereotypy to Design Tailored Immunotherapy in Chronic Lymphocytic Leukemia by Rovida, Alessandra, Maccalli, Cristina, Scarfò, Lydia, Dellabona, Paolo, Stamatopoulos, Kostas, Ghia, Paolo

“…Approximately 30% of patients with chronic lymphocytic leukemia (CLL) can be grouped into subsets with stereotyped B-cell receptor immunoglobulin (BcR IG)…”
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COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus by Scarfò, Lydia, Chatzikonstantinou, Thomas, Rigolin, Gian Matteo, Quaresmini, Giulia, Motta, Marina, Vitale, Candida, Garcia-Marco, Jose Antonio, Hernández-Rivas, José Ángel, Mirás, Fatima, Baile, Mónica, Marquet, Juan, Niemann, Carsten U., Reda, Gianluigi, Munir, Talha, Gimeno, Eva, Marchetti, Monia, Quaglia, Francesca Maria, Varettoni, Marzia, Delgado, Julio, Iyengar, Sunil, Janssens, Ann, Marasca, Roberto, Ferrari, Angela, Cuéllar-García, Carolina, Itchaki, Gilad, Špaček, Martin, De Paoli, Lorenzo, Laurenti, Luca, Levin, Mark-David, Lista, Enrico, Mauro, Francesca R., Šimkovič, Martin, Van Der Spek, Ellen, Vandenberghe, Elisabeth, Trentin, Livio, Wasik-Szczepanek, Ewa, Ruchlemer, Rosa, Bron, Dominique, De Paolis, Maria Rosaria, Del Poeta, Giovanni, Farina, Lucia, Foglietta, Myriam, Gentile, Massimo, Herishanu, Yair, Herold, Tobias, Jaksic, Ozren, Kater, Arnon P., Kersting, Sabina, Malerba, Lara, Orsucci, Lorella, Popov, Viola Maria, Sportoletti, Paolo, Yassin, Mohamed, Pocali, Barbara, Barna, Gabor, Chiarenza, Annalisa, dos Santos, Gimena, Nikitin, Eugene, Andres, Martin, Dimou, Maria, Doubek, Michael, Enrico, Alicia, Hakobyan, Yervand, Kalashnikova, Olga, Ortiz Pareja, Macarena, Papaioannou, Maria, Rossi, Davide, Shah, Nimish, Shrestha, Amit, Stanca, Oana, Stavroyianni, Niki, Strugov, Vladimir, Tam, Constantine, Zdrenghea, Mihnea, Coscia, Marta, Stamatopoulos, Kostas, Rossi, Giuseppe, Rambaldi, Alessandro, Montserrat, Emili’, Foà, Robin, Cuneo, Antonio, Ghia, Paolo

“…Chronic lymphocytic leukemia (CLL) is a disease of the elderly, characterized by immunodeficiency. Hence, patients with CLL might be considered more…”
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Olaptesed pegol (NOX-A12) with bendamustine and rituximab: a phase IIa study in patients with relapsed/refractory chronic lymphocytic leukemia by Steurer, Michael, Montillo, Marco, Scarfò, Lydia, Mauro, Francesca R, Andel, Johannes, Wildner, Sophie, Trentin, Livio, Janssens, Ann, Burgstaller, Sonja, Frömming, Anna, Dümmler, Thomas, Riecke, Kai, Baumann, Matthias, Beyer, Diana, Vauléon, Stéphanie, Ghia, Paolo, Foà, Robin, Caligaris-Cappio, Federico, Gobbi, Marco

“…Olaptesed pegol (NOX-A12) is a pegylated structured L-oligoribonucleotide that binds and neutralizes CXCL12, a chemokine tightly regulating the life cycle of…”
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Efficacy and safety of dinaciclib vs ofatumumab in patients with relapsed/refractory chronic lymphocytic leukemia by Ghia, Paolo, Scarfò, Lydia, Perez, Susan, Pathiraja, Kumudu, Derosier, Martha, Small, Karen, McCrary Sisk, Christine, Patton, Nigel

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Three-dimensional co-culture model of chronic lymphocytic leukemia bone marrow microenvironment predicts patient-specific response to mobilizing agents by Barbaglio, Federica, Belloni, Daniela, Scarfò, Lydia, Sbrana, Francesca Vittoria, Ponzoni, Maurilio, Bongiovanni, Lucia, Pavesi, Luca, Zambroni, Desiree, Stamatopoulos, Kostas, Caiolfa, Valeria R, Ferrero, Elisabetta, Ghia, Paolo, Scielzo, Cristina

“…Chronic Lymphocytic Leukemia (CLL) cells disseminate into supportive tissue microenvironments. To investigate the mechanisms involved in leukemic cell tissue…”
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Monoclonal B cell lymphocytosis and “in situ” lymphoma by Karube, Kennosuke, Scarfò, Lydia, Campo, Elias, Ghia, Paolo

“…Abstract The finding of monoclonal B-cell populations not fulfilling criteria for a lymphoid malignancy has given great impulse to study mechanisms involved in…”
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BTK Inhibition Impairs the Innate Response Against Fungal Infection in Patients With Chronic Lymphocytic Leukemia by Fiorcari, Stefania, Maffei, Rossana, Vallerini, Daniela, Scarfò, Lydia, Barozzi, Patrizia, Maccaferri, Monica, Potenza, Leonardo, Ghia, Paolo, Luppi, Mario, Marasca, Roberto

“…Infections represent a cause of morbidity and mortality in patients affected by chronic lymphocytic leukemia (CLL). Introduction of new drugs in CLL clinical…”
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Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations by Agathangelidis, Andreas, Ljungström, Viktor, Scarfò, Lydia, Fazi, Claudia, Gounari, Maria, Pandzic, Tatjana, Sutton, Lesley-Ann, Stamatopoulos, Kostas, Tonon, Giovanni, Rosenquist, Richard, Ghia, Paolo

“…Despite the recent discovery of recurrent driver mutations in chronic lymphocytic leukemia, the genetic factors involved in disease onset remain largely…”
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Acalabrutinib: a highly selective, potent Bruton tyrosine kinase inhibitor for the treatment of chronic lymphocytic leukemia by Ghia, Paolo, Dlugosz-Danecka, Monika, Scarfò, Lydia, Jurczak, Wojciech

“…Inhibiting the activity of Bruton tyrosine kinase (BTK) prevents the activation of the B-cell receptor (BCR) signaling pathway, which in turn prevents both…”
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