Search Results - "Lyall, D M"

Adiposity among 132 479 UK Biobank participants; contribution of sugar intake vs other macronutrients by Anderson, J J, Celis-Morales, C A, Mackay, D F, Iliodromiti, S, Lyall, D M, Sattar, N, Gill, Jmr, Pell, J P

“…Policy makers are being encouraged to specifically target sugar intake in order to combat obesity. We examined the extent to which sugar, relative to other…”
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Cannabis use and risk of schizophrenia: a Mendelian randomization study by Vaucher, J, Keating, B J, Lasserre, A M, Gan, W, Lyall, D M, Ward, J, Smith, D J, Pell, J P, Sattar, N, Paré, G, Holmes, M V

“…Cannabis use is observationally associated with an increased risk of schizophrenia, but whether the relationship is causal is not known. Using a genetic…”
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Post-intravitreal anti-VEGF endophthalmitis in the United Kingdom: incidence, features, risk factors, and outcomes by Lyall, D A M, Tey, A, Foot, B, Roxburgh, S T D, Virdi, M, Robertson, C, MacEwen, C J

“…Purpose To describe the incidence, features, management, and risk factors of post-intravitreal anti-VEGF endophthalmitis (PIAE) in patients undergoing…”
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Increased risk of lower limb osteoarthritis among former professional soccer (football) players by Russell, E R, Spencer, S J, Atherton, C M, Lyall, D M, Mackay, D F, Stewart, K, MacLean, J A, Pell, J P, Stewart, W

“…Abstract Background Soccer is a high-speed contact sport with risk of injury. Despite long-standing concern, evidence to date remains inconsistent as to the…”
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The association between driving time and unhealthy lifestyles: a cross-sectional, general population study of 386 493 UK Biobank participants by Mackay, A, Mackay, D F, Celis-Morales, C A, Lyall, D M, Gray, S R, Sattar, N, Gill, J M R, Pell, J P, Anderson, J J

“…Driving is a common type of sedentary behaviour; an independent risk factor for poor health. The study explores whether driving is also associated with other…”
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Implantation of a customized toric intraocular lens for correction of post-keratoplasty astigmatism by Srinivasan, S, Ting, D S J, Lyall, D A M

“…Purpose To report visual and refractive outcomes, and endothelial cell loss following primary and secondary ‘piggyback’ toric intraocular lens (IOL)…”
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Intravitreal Ranibizumab in the treatment of choroidal neovascularisation secondary to ocular toxocariasis in a 13-year-old boy by Lyall, D A M, Hutchison, B M, Gaskell, A, Varikkara, M

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Bilateral endogenous Serratia marcescens endophthalmitis secondary to endocarditis following cardiac surgery by Lyall, D A M, Gregory, M E, McDonnell, J, De Villiers, F, Tejwani, D

“…Endogenous endophthalmitis is a sight-threatening condition caused by microorganisms crossing the blood-ocular barrier and inducing profound intraocular…”
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P3823Body mass index or waist and hip circumference as predictors of outcome in the UK biobank by Pellicori, P, Stanley, B, Iliodromiti, S, Celis-Morales, C A, Lyall, D M, Anderson, J, Gray, S, Mackay, D F, Nelson, S M, Welsh, P, Pell, J P, Gill, J M R, Sattar, N, Cleland, J G F

“…Abstract Background Controversies exist about the relationship between body habitus and mortality, especially for patients with cardiovascular disease. Purpose…”
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Sugar-sweetened beverages intake associates with all-cause mortality independently of other dietary and lifestyle factors and obesity by Anderson, J. J., Gray, S.R., Iliodromity, S., Welch, P., MacKay, D.F., Celis-Morales, C.A., Lyall, D.M., Gill, J.M.R., Sattar, N., Pell, J.P.

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Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants by Celis-Morales, C A, Lyall, D M, Gray, S R, Steell, L, Anderson, J, Iliodromiti, S, Welsh, P, Guo, Y, Petermann, F, Mackay, D F, Bailey, M E S, Pell, J P, Gill, J M R, Sattar, N

“…Background: Obesity is a multifactorial condition influenced by both genetics and lifestyle. The aim of this study was to investigate whether the association…”
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Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK Biobank by Lyall, Laura M, Wyse, Cathy A, Graham, Nicholas, Ferguson, Amy, Lyall, Donald M, Cullen, Breda, Celis Morales, Carlos A, Biello, Stephany M, Mackay, Daniel, Ward, Joey, Strawbridge, Rona J, Gill, Jason M R, Bailey, Mark E S, Pell, Jill P, Smith, Daniel J

“…Disruption of sleep and circadian rhythmicity is a core feature of mood disorders and might be associated with increased susceptibility to such disorders…”
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Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91105 participants from the UK Biobank by Lyall, LM, Wyse, CA, Graham, N, Ferguson, A, Lyall, DM, Cullen, B, Morales, CAC, Biello, SM, Mackay, D, Ward, J

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Subjective and objective sleep and circadian parameters as predictors of depression-related outcomes: A machine learning approach in UK Biobank by Lyall, Laura M., Sangha, Natasha, Zhu, Xingxing, Lyall, Donald M., Ward, Joey, Strawbridge, Rona J., Cullen, Breda, Smith, Daniel J.

“…Sleep and circadian disruption are associated with depression onset and severity, but it is unclear which features (e.g., sleep duration, chronotype) are…”
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The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function by Ward, Joey, Tunbridge, Elizabeth M., Sandor, Cynthia, Lyall, Laura M., Ferguson, Amy, Strawbridge, Rona J., Lyall, Donald M., Cullen, Breda, Graham, Nicholas, Johnston, Keira J. A., Webber, Caleb, Escott-Price, Valentina, O’Donovan, Michael, Pell, Jill P., Bailey, Mark E. S., Harrison, Paul J., Smith, Daniel J.

“…Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness…”
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Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank by Hay, Rachel, Cullen, Breda, Graham, Nicholas, Lyall, Donald M, Aman, Alisha, Pell, Jill P, Ward, Joey, Smith, Daniel J, Strawbridge, Rona J

“…The association between severe mental illness (SMI) and cardiovascular and metabolic disease (CMD) is poorly understood. PCSK9 is expressed in systems critical…”
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Testing for associations between HbA1c levels, polygenic risk and brain health in UK Biobank (N = 39 283) by Ranglani, Sanskar, Ward, Joey, Sattar, Naveed, Strawbridge, Rona J., Lyall, Donald M.

“…Aim To investigate whether continuous HbA1c levels and HbA1c‐polygenic risk scores (HbA1c‐PRS) are significantly associated with worse brain health independent…”
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Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization by Aman, Alisha, Slob, Eric A W, Ward, Joey, Cullen, Breda, Graham, Nicholas, Lyall, Donald M, Sattar, Naveed, Strawbridge, Rona J

“…Prescription of PCSK9-inhibitors has increased in recent years but not much is known about its off-target effects. PCSK9-expression is evident in non-hepatic…”
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Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UK Biobank by Strawbridge, Rona J., Ward, Joey, Bailey, Mark E.S., Cullen, Breda, Ferguson, Amy, Graham, Nicholas, Johnston, Keira J.A., Lyall, Laura M., Pearsall, Robert, Pell, Jill, Shaw, Richard J., Tank, Rachana, Lyall, Donald M., Smith, Daniel J.

“…OBJECTIVE:Atherosclerosis is the underlying cause of most cardiovascular disease, but mechanisms underlying atherosclerosis are incompletely understood…”
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Genetic architecture of DCC and influence on psychological, psychiatric and cardiometabolic traits in multiple ancestry groups in UK Biobank by Forsyth, Lewis, Aman, Alisha, Cullen, Breda, Graham, Nicholas, Lyall, Donald M., Lyall, Laura M., Pell, Jill P., Ward, Joey, Smith, Daniel J., Strawbridge, Rona J.

“…People with severe mental illness have a higher risk of cardiometabolic disease than the general population. Traditionally attributed to sociodemographic,…”
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