Search Results - "Lyakhovich, Vyacheslav V"

Menadione Suppresses Benzo(α)pyrene-Induced Activation of Cytochromes P450 1A: Insights into a Possible Molecular Mechanism by Sidorova, Yulia A, Perepechaeva, Maria L, Pivovarova, Elena N, Markel, Arkady L, Lyakhovich, Vyacheslav V, Grishanova, Alevtina Y

“…Oxidative reactions that are catalyzed by cytochromes P450 1A (CYP1A) lead to formation of carcinogenic derivatives of arylamines and polycyclic aromatic…”
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The gene expression profile of a drug metabolism system and signal transduction pathways in the liver of mice treated with tert-butylhydroquinone or 3-(3'-tert-butyl-4'-hydroxyphenyl)propylthiosulfonate of sodium by Shintyapina, Alexandra B, Vavilin, Valentin A, Safronova, Olga G, Lyakhovich, Vyacheslav V

“…Tert-butylhydroquinone (tBHQ) is a highly effective phenolic antioxidant used in edible oils and fats in foods as well as in medicines and cosmetics. TBHQ has…”
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Association of cytochrome P450 genetic polymorphisms with neoadjuvant chemotherapy efficacy in breast cancer patients by Seredina, Tatyana A, Goreva, Olga B, Talaban, Valeria O, Grishanova, Alevtina Yu, Lyakhovich, Vyacheslav V

“…The enzymes of the cytochrome P450 family (CYPs) play an important role in the metabolism of a great variety of anticancer agents; therefore, polymorphisms in…”
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Comparative study of CYP2B induction in the liver of rats and mice by different compounds by Pustylnyak, Vladimir O., Lebedev, Anton N., Gulyaeva, Lyudmila F., Lyakhovich, Vyacheslav V., Slynko, Nikolaj M.

“…Male Wistar rats and C57BL mice were treated by phenobarbital (PB), 2,4,6-triphenyldioxane-1,3 (TPD) and 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP)…”
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CAR expression and inducibility of CYP2B genes in liver of rats treated with PB-like inducers by Pustylnyak, Vladimir O., Gulyaeva, Lyudmila F., Lyakhovich, Vyacheslav V.

“…The expression of the CAR gene and inducibility of CYP2B protein in the liver of male Wistar rats treated with phenobarbital (PB) and triphenyldioxane (TPD)…”
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In vivo effects of protein kinase and phosphatase inhibitors on CYP2B induction in rat liver by Pustylnyak, Vladimir O., Zakharova, Lyudmila Yu, Mikhailova, Olga N., Rice, Robert H., Gulyaeva, Lyudmila F., Lyakhovich, Vyacheslav V.

“…Effects of inhibiting protein kinases and phosphatases on induction of CYP2B by triphenyldioxane (TPD) and phenobarbital (PB) were investigated. Male Wistar…”
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Cytochrome P4501A1 and 1A2 Gene Expression in the Liver of 3-Methylcholanthrene- and o-Aminoazotoluene-Treated Mice: A Comparison between PAH-Responsive and PAH-Nonresponsive Strains by Zacharova, Ludmila Yu, Gulyaeva, Ludmila F., Lyakhovich, Vyacheslav V., Mikhailova, Olga N., Timofeeva, Olga A., Filipenko, Maxim L., Kaledin, Vasily I.

“…The objective of this study was to investigate cytochrome P4501A1 and 1A2 mRNA, protein, and enzyme activity in the liver of male mice differing in the aryl…”
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The gene expression profile of a drug metabolism system and signal transduction pathways in the liver of mice treated with tert-butylhydroquinone or 3 by Shintyapina, Alexandra B, Vavilin, Valentin A, Safronova, Olga G, Lyakhovich, Vyacheslav V

“…Tert-butylhydroquinone (tBHQ) is a highly effective phenolic antioxidant used in edible oils and fats in foods as well as in medicines and cosmetics. TBHQ has…”
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Menadione Suppresses Benzopyrene-Induced Activation of Cytochromes P450 1A: Insights into a Possible Molecular Mechanism by Sidorova, Yulia A, Perepechaeva, Maria L, Pivovarova, Elena N, Markel, Arkady L, Lyakhovich, Vyacheslav V, Grishanova, Alevtina Y

“…Oxidative reactions that are catalyzed by cytochromes P450 1A (CYP1A) lead to formation of carcinogenic derivatives of arylamines and polycyclic aromatic…”
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CAR expression and inducibility of CYP2B genes in liver of rats treated with PB-like inducers by PUSTYLNYAK, Vladimir O, GULYAEVA, Lyudmila F, LYAKHOVICH, Vyacheslav V

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An in vivo-in vitro comparison of the effects of bile acids on the structural organization and functional activity of liver microsomal monooxygenases by Tsyrlov, I B, Zakharova-Polyakova, N E, Gromova, O A, Pospelova, L N, Lyakhovich, V V

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In vivo effects of protein kinase and phosphatase inhibitors on CYP2B induction in rat liver by PUSTYLNYAK, Vladimir O, ZAKHAROVA, Lyudmila Yu, MIKHAILOVA, Olga N, RICE, Robert H, GULYAEVA, Lyudmila F, LYAKHOVICH, Vyacheslav V

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Phenobarbital-dependent protein binding to Barbie box-like sequences in the coding region of cytochrome P450 BM-3 gene from Bacillus megaterium by Gaidamakova, Elena K., Alpatov, Oleg V., Ischenko, Igor V., Kovalenko, Sergei P., Lyakhovich, Vyacheslav V.

“…Phenobarbital-dependent protein binding was shown to occur to DNA fragments from the coding region of the cytochrome P450 BM-3 gene from Bacillus megaterium…”
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Phenobarbital-dependent protein binding to Barbie box-like sequences in the coding region of cytochrome P450BM-3 gene from Bacillus megaterium by Gaidamakova, E K, Alpatov, O V, Ischenko, I V, Kovalenko, S P, Lyakhovich, V V

“…Phenobarbital-dependent protein binding was shown to occur to DNA fragments from the coding region of the cytochrome P450BM-3 gene from Bacillus megaterium…”
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The phenobarbital-type induction of rat liver microsomal monooxygenases by perfluorodecalin by Mishin, V M, Obraztsov, V V, Grishanova AYu, Gutkina, N I, Shekhtman, D G, Khatsenko, O G, Lyakhovich, V V

“…Induction of perfluorodecalin (PFD) of the liver microsomal system of metabolism of xenobiotics has been studied and compared with the inductions by…”
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Rate-limiting steps in drug metabolism by microsomes from CCl-4-cirrhotic rat liver by Tsyrlov, I B, Lyakhovich, V V

“…Comparative studies have been conducted of the activity of microsomal mixed-function oxidases from livers of normal, precirrhotic and cirrhotic rats linked…”
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Possible mechanism of induction of liver microsomal monooxygenases by phenobarbital by Tsyrlov, I B, Zakharova, N E, Gromova, O A, Lyakhovich, V V

“…A study has been made of a model of "consecutive" induction of microsomal monooxygenases following treatment with phenobarbital which was administered after…”
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Cholestasis as an in vivo model for analysis of the induction of liver microsomal monooxygenases by sodium phenobarbital and 3-methylcholanthrene by Tsyrlov, I B, Polyakova, N E, Gromova, O A, Rivkind, N B, Lyakhovich, V V

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Induction and catalytic activities of cytochromes P-450b/e and P-450c in the liver microsomes of neonatal rats by Gulyaeva, L F, Mishin, V M, Lyakhovich, V V

“…The activities of cytochrome P-450-dependent monooxygenases has been investigated in the liver microsomes of newborn rats (3-16 days after birth) induced with…”
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Activities of 3,4-benzpyrene hydroxylase systems reconstituted by means of self-assembly from control and 3-methylcholanthrene-induced liver microsomes of "susceptible" and "unsusceptible" mice by Lyakhovich, V V, Tsyrlov, I B, Gromova, O A, Rivkind, N B

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