Bacterial Violacein: Properties, Biosynthesis and Application Prospects

Bacterial Violacein: Properties, Biosynthesis and Application Prospects

This review discusses the properties of violacein, a chromogenic secondary metabolite of bacteria with a wide range of biological activity, as well as the issues of its microbial synthesis and prospects for application. Violacein-synthesizing bacteria have been isolated from various sources, includi...

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Bibliographic Details
Published in:Applied biochemistry and microbiology Vol. 58; no. 6; pp. 692 - 700
Main Authors: Lyakhovchenko, N. S., Travkin, V. M., Senchenkov, V. Yu, Solyanikova, I. P.
Format: Journal Article
Language:English
Published: Moscow Pleiades Publishing 01-12-2022
Springer Nature B.V
Subjects:
Anticancer properties
Antimicrobial agents
Bacteria
Bioactive compounds
Biochemistry
Biological activity
Biomedical and Life Sciences
Biosynthesis
Cultivated plants
Drug development
Glaciers
Life Sciences
Medical Microbiology
Meltwater
Metabolites
Microbiology
Microorganisms
Plant protection
Rhizosphere
Veterinary medicine
Violacein
secondary metabolites
pigments
violacein
biotechnological significance
antimicrobial activity
insecticides
cytotoxicity
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Summary:This review discusses the properties of violacein, a chromogenic secondary metabolite of bacteria with a wide range of biological activity, as well as the issues of its microbial synthesis and prospects for application. Violacein-synthesizing bacteria have been isolated from various sources, including the rhizosphere of cultivated plants, soils, marshes, sea coasts, ponds, and glacier melt waters. The study of the antibacterial, antimycotic, insecticidal, and antitumor properties of violacein makes it an extremely promising biologically active compound and causes a steadily increasing interest in both the compound itself and in the group of bacteria that produce it, in terms of the development of new drugs and veterinary drugs, as well as plant protection products. The purpose of this review is to attempt to summarize the considerable amount of data on this compound, especially regarding its antimicrobial and anticancer properties.
ISSN:0003-6838
1608-3024
DOI:10.1134/S0003683822060072