Search Results - "Lyadova, I. V."

Th1 and Th17 Cells in Tuberculosis: Protection, Pathology, and Biomarkers by Lyadova, I. V., Panteleev, A. V.

“…The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete pathogen clearance through asymptomatic latent infection (LTBI) to active…”
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Early markers of induced pluripotent stem cell hematopoietic development by Sheveleva, O. N., Nenasheva, T. A., Lyadova, I. V.

“…The generation of immune cell populations from induced pluripotent stem cells (iPSCs) is a valuable model to study mechanisms that control hematopoietic…”
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Hemapoietic Stem Cell and Initial Stages of Hemopoiesis: Research Methods and Modern Concepts by Sheveleva, O. N., Lyadova, I. V.

“…Hematopoietic stem cells (HSCs) have long been one of the most well-studied type of stem cells. Multiple experimental and clinical studies allowed for…”
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Intranasal BCG vaccination protects BALB/c mice against virulent Mycobacterium bovis and accelerates production of IFN‐γ in their lungs by Lyadova, I. V., Vordermeier, H. M., Eruslanov, E. B., Khaidukov, S. V., Apt, A. S., Hewinson, R. G.

“…Local immune reactivity in the lungs of BALB/c mice was studied following (i) intranasal (i.n.) vaccination with Mycobacterium bovis BCG, (ii) intravenous…”
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COVID-19 and BCG vaccine: is there a link? by Lyadova, I. V., Starikov, A. A.

“…The spread of the novel coronavirus infection (COVID-19) makes the search for new approaches to prevent the infection of great importance. As one of the…”
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Mesenchymal Stem Cell Therapy—Is the Vessel Half Full or Half Empty? by Sukhanov, Yu. V., Vorotelyak, E. A., Lyadova, I. V., Vasiliev, A. V.

“…The urgency of the search and introduction into medical practice of the method for the therapy of severe forms of pneumonia COVID-19 is due to the lack of…”
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The 19‐kD antigen and protective immunity in a murine model of tuberculosis by Yeremeev, V. V., Lyadova, I. V., Nikonenko, B. V., Apt, A. S., Abou‐Zeid, C., Inwald, J., Young, D. B.

“…The 19‐kD antigen is a cell wall‐associated lipoprotein present in Mycobacterium tuberculosis and in bacille Calmette–Guérin (BCG) vaccine strains. Expression…”
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Characterization of T cell clones derived from lymph nodes and lungs of Pseudomonas aeruginosa‐susceptible and resistant mice following immunization with heat‐killed bacteria by Kondratieva, T. K., Kobets, N. V., Khaidukov, S. V., Yeremeev, V. V., Lyadova, I. V., Apt, A. S., Tam, M. F., Stevenson, M. M.

“…Pseudomonas aeruginosa‐resistant BALB/c and susceptible C57Bl/6 (B6) mice were immunized with heat‐killed Pseudomonas either in the foot pad or via the…”
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Association of Tuberculosis and Infections of Herpes Simplex, Varicella Zoster Viruses and Cytomegalovirus by Kazanova, A. S., Lavrov, V. F., Panteleev, A. V., Lyadova, I. V.

“…To determine frequency of Herpes simplex (HSV), Varicella zoster viral (VZV) and Сytomegaloviral (CMV) coinfection with tuberculosis (TB) we examined 45…”
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Lung cell responses to M. tuberculosis in genetically susceptible and resistant mice following intratracheal challenge by ERUSLANOV, E. B., MAJOROV, K. B., ORLOVA, M. O., MISCHENKO, V. V., KONDRATIEVA, T. K., APT, A. S., LYADOVA, I. V.

“…SUMMARY One approach to study the role of distinct cellular mechanisms in susceptibility/resistance to tuberculosis (TB) is to compare parameters of response…”
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CD4 T cells producing IFN‐γ in the lungs of mice challenged with mycobacteria express a CD27‐negative phenotype by LYADOVA, I. V., OBERDORF, S., KAPINA, M. A., APT, A. S., SWAIN, S. L., SAYLES, P. C.

“…SUMMARY Protection against tuberculosis depends upon the generation of CD4+ T cell effectors capable of producing IFN‐γ and stimulating macrophage…”
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Comparative Analysis of T Lymphocytes Recovered from the Lungs of Mice Genetically Susceptible, Resistant, and Hyperresistant to Mycobacterium tuberculosis-Triggered Disease by Lyadova, Irina V, Eruslanov, Evgenyi B, Khaidukov, Sergei V, Yeremeev, Vladimir V, Majorov, Konstantin B, Pichugin, Alexander V, Nikonenko, Boris V, Kondratieva, Tatiana K, Apt, Alexander S

“…Genetic control of susceptibility to tuberculosis (TB) is being intensively studied, and immune responses to mycobacteria are considerably well characterized…”
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Neutrophils in Tuberculosis: Heterogeneity Shapes the Way? by Lyadova, I. V.

“…Infection with M. tuberculosis remains one of the most common infections in the world. The outcome of the infection depends on host ability to mount effective…”
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Preparation and characterization of mycobacterial antigen-specific T-cell clones from mice with genetically different sensitivity to tuberculosis by Eremeev, V. V., Lyadova, I. V., Maiorov, K. B., Khaidukov, S. V., Moroz, A. M., Apt, A. S.

“…T-clones specific for purified protein derivative of tuberculin are derived from mice with genetically different sensitivity to tuberculosis. The absolute…”
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Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation by Nenasheva, Tatiana, Nikolaev, Alexander, Sosunova, Ekaterina, Lyadova, I. V.

“…To protect host against immune-mediated damage, immune responses are tightly regulated. The regulation of immune responses is mediated by various populations…”
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TH1 lymphocytes: correlates of protection or markers of tuberculosis infection activity? by Lyadova, I. V., Panteleev, A. V., Nikitina, I. Yu, Radaeva, T. V.

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Antigen-Specific IFN-γ Responses Correlate with the Activity of M. tuberculosis Infection but Are Not Associated with the Severity of Tuberculosis Disease by Lyadova, I. V., Vasilyeva, Irina A., Andreevskaya, Sofia N., Burmistrova, Irina A., Bagdasarian, Tatef R., Karpina, Natalya L., Sosunova, Ekaterina, Panteleev, A. V., Nikitina, Irina Yu, Chernousova, Larisa N.

“…IFN-γ is a key cytokine in antituberculosis (TB) defense. However, how the levels of its secretion affect M. tuberculosis (Mtb) infection is not clear. We have…”
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Delayed-type hypersensitivity to transplantation antigens in mice and its investigation under conditions of allograft and xenograft tolerance by Chernyakhovskaya IYu, Lyadova, I V

“…Methods of induction of delayed-type hypersensitivity (DTH) to transplantation alloantigens and xenoantigens in mice were developed. They include the s.c…”
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Mycobacterial Dissemination and Cellular Responses after 1-Lobe Restricted Tuberculosis Infection of Genetically Susceptible and Resistant Mice by Mischenko, Vladimir V., Kapina, Marina A., Eruslanov, Evgenyi B., Kondratieva, Elena V., Lyadova, Irina V., Young, Douglas B., Apt, Alexander S.

“…Background and methods. To study mycobacterial dissemination and immune-cell trafficking in tuberculosis, we developed a mouse model in which we introduced 1…”
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CD4 T cells producing IFN-(gamma) in the lungs of mice challenged with mycobacteria express a CD27-negative phenotype by Lyadova, I V, Oberdorf, S, Kapina, M A, Apt, A S

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