Flavonoids and Alkaloids from Marine‐Derived Actinomycete Streptomyces sp. C011

Five secondary metabolites including three flavonoids, 6‐lavandulyl‐5,7,2′,4′‐tetrahydroxyflavanone (1), 5′‐lavandulyl‐2′‐methoxy‐2,4,4′,6′‐tetrahydroxychalcone (2), 6‐lavandulyl‐7‐methoxy‐5,2′,4′‐trihydroxyflavanone (3), and two alkaloids, tryptoline (4), and norharman (5) were isolated from the cu...

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Bibliographic Details
Published in:	Vietnam journal of chemistry Vol. 58; no. 5; pp. 610 - 614
Main Authors:	Hoa, Tran Thi Thanh, Van Nam, Vu, Huong, Doan Thi Mai, Dao, Phi Thi, Phuong, Nguyen Nam, Minh, Le Thi Hong, Quyen, Vu Thi, Anh, Nguyen Mai, Murphy, Brian T., Ly, Ho Thi Minh, Van Cuong, Pham
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY‐VCH Verlag GmbH & Co. KGaA 01-10-2020
Subjects:	actinomycetes alkaloid flavonoid marine microorganism Streptomyces
Online Access:	Get full text
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Summary:	Five secondary metabolites including three flavonoids, 6‐lavandulyl‐5,7,2′,4′‐tetrahydroxyflavanone (1), 5′‐lavandulyl‐2′‐methoxy‐2,4,4′,6′‐tetrahydroxychalcone (2), 6‐lavandulyl‐7‐methoxy‐5,2′,4′‐trihydroxyflavanone (3), and two alkaloids, tryptoline (4), and norharman (5) were isolated from the culture broth of Streptomyces sp. C011. Their structures were determined by spectral data analysis, including MS, 2D NMR, and CD spectrum. All the separated compounds were evaluated for their antimicrobial activities. Compounds 1, 2, 3 and 5 exhibited antimicrobial activity.
ISSN:	0866-7144 2572-8288 2572-8288
DOI:	10.1002/vjch.202000046