Search Results - "Lv, Shixian"

Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application by Song, Ziyuan, Han, Zhiyuan, Lv, Shixian, Chen, Chongyi, Chen, Li, Yin, Lichen, Cheng, Jianjun

“…Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides (NCAs) are one of the most important biomaterials. The unique features of…”
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Co-delivery of doxorubicin and paclitaxel by PEG-polypeptide nanovehicle for the treatment of non-small cell lung cancer by Lv, Shixian, Tang, Zhaohui, Li, Mingqiang, Lin, Jian, Song, Wantong, Liu, Huaiyu, Huang, Yubin, Zhang, Yuanyuan, Chen, Xuesi

“…Abstract Despite progress, combination therapy of different functional drugs to increase the efficiency of anticancer treatment still remains challenges. An…”
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Applications of Nanobiomaterials in the Therapy and Imaging of Acute Liver Failure by Jin, Yuanyuan, Wang, Haixia, Yi, Ke, Lv, Shixian, Hu, Hanze, Li, Mingqiang, Tao, Yu

“…Highlights This review focuses on the therapeutic mechanisms, targeting strategies of various nanomaterials in acute liver failure, and recent advances of…”
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Improved antitumor immunity of chemotherapy in OSCC treatment by Gasdermin-E mediated pyroptosis by Zi, Mei, Xingyu, Chen, Yang, Chen, Xiaodong, Su, Shixian, Lv, Shicheng, Wei

“…Oral squamous cell carcinoma (OSCC) is a malignant tumor with high mortality and poor prognosis. Many OSCC patients have low response rate to current…”
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Photodynamic therapy-triggered on-demand drug release from ROS-responsive core-cross-linked micelles toward synergistic anti-cancer treatment by Li, Yongjuan, Hu, Jian, Liu, Xun, Liu, Yong, Lv, Shixian, Dang, Juanjuan, Ji, Yong, He, Jinlin, Yin, Lichen

“…Polymeric micelles have demonstrated wide utility for chemodrug delivery, which however, still suffer from shortcomings such as undesired drug loading,…”
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3D printed hydrogel scaffolds combining glutathione depletion-induced ferroptosis and photothermia-augmented chemodynamic therapy for efficiently inhibiting postoperative tumor recurrence by Dang, Wentao, Chen, Wei-Chih, Ju, Enguo, Xu, Yanteng, Li, Kai, Wang, Haixia, Wang, Kun, Lv, Shixian, Shao, Dan, Tao, Yu, Li, Mingqiang

“…Surgical resection to achieve tumor-free margins represents a difficult clinical scenario for patients with hepatocellular carcinoma. While post-surgical…”
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Editorial: Synthesis, functionalization, and clinical translation of pharmaceutical biomaterials by Zhou, Huicong, Lv, Shixian, Li, Mingqiang, Ding, Jianxun

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Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure by Jin, Yuanyuan, Zhang, Jiabin, Xu, Yanteng, Yi, Ke, Li, Fenfang, Zhou, Huicong, Wang, Haixia, Chan, Hon Fai, Lao, Yeh-Hsing, Lv, Shixian, Tao, Yu, Li, Mingqiang

“…Reactive oxygen species (ROS)-associated oxidative stress, inflammation storm, and massive hepatocyte necrosis are the typical manifestations of acute liver…”
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Editorial: Synthesis, Functionalization, and Clinical Translation of Pharmaceutical Biomaterials by Kong, Huimin, Lv, Shixian, Li, Mingqiang, Ding, Jianxun

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In situ sustained release hydrogel system delivering GLUT1 inhibitor and chemo-drug for cancer post-surgical treatment by Wang, Lanqing, Mei, Zi, Jin, Guanyu, Liu, Hao, Lv, Shixian, Fu, Runjia, Li, Muxing, Yao, Cuiping

“…Systematic administration of small molecular drugs often suffered from the low efficacy and systemic toxicity in cancer therapy. In addition, application of…”
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Nanoparticles exhibit greater accumulation in kidney glomeruli during experimental glomerular kidney disease by Liu, Gary W., Pippin, Jeffrey W., Eng, Diana G., Lv, Shixian, Shankland, Stuart J., Pun, Suzie H.

“…Loss and dysfunction of glomerular podocytes result in increased macromolecule permeability through the glomerular filtration barrier and nephrotic syndrome…”
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Polymeric immunogel prevents tumor recurrence and metastasis by dual activation of innate and adaptive immunity by Jin, Guanyu, Liu, Hao, Mei, Zi, Jin, Qionghua, Ma, Sheng, Wang, Lanqing, Su, Yuanzhen, Lv, Letian, Wang, Zijuan, Zhou, Huicong, Li, Mingqiang, Huang, Zehuan, Chen, Xuesi, Lv, Shixian

“…Tumor recurrence and metastasis after surgery are important factors affecting patient survival. The immunosuppressed tumor microenvironment after surgery…”
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Development of stimuli responsive polymeric nanomedicines modulating tumor microenvironment for improved cancer therapy by Su, Yuanzhen, Jin, Guanyu, Zhou, Huicong, Yang, Zhaofan, Wang, Lanqing, Mei, Zi, Jin, Qionghua, Lv, Shixian, Chen, Xuesi

“…The complexity of the tumor microenvironment (TME) severely hinders the therapeutic effects of various cancer treatment modalities. The TME differs from normal…”
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Tunable pH-Sensitive Poly(β-amino ester)s Synthesized from Primary Amines and Diacrylates for Intracellular Drug Delivery by Song, Wantong, Tang, Zhaohui, Li, Mingqiang, Lv, Shixian, Yu, Haiyang, Ma, Lili, Zhuang, Xiuli, Huang, Yubin, Chen, Xuesi

“…The pH sensitivity of a series of PbAEs synthesized from primary amines and diacrylates is studied. By changing alkyl groups of the amine monomers, the pKb can…”
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Synergistic Antitumor Effects of Doxorubicin-Loaded Carboxymethyl Cellulose Nanoparticle in Combination with Endostar for Effective Treatment of Non-Small-Cell Lung Cancer by Li, Mingqiang, Tang, Zhaohui, Lin, Jian, Zhang, Yu, Lv, Shixian, Song, Wantong, Huang, Yubin, Chen, Xuesi

“…The multi‐modal combination therapy is proved powerful and successful to enhance the antitumor efficacy in clinics as compared with single therapy modes. In…”
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Rationally Designed Polymer Conjugate for Tumor-Specific Amplification of Oxidative Stress and Boosting Antitumor Immunity by Ma, Sheng, Song, Wantong, Xu, Yudi, Si, Xinghui, Lv, Shixian, Zhang, Yu, Tang, Zhaohui, Chen, Xuesi

“…The crosstalk between tumor and stroma cells is a central scenario in the tumor microenvironment (TME). While the predominant effect of tumor cells on immune…”
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High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor–Receptor Coordination Interactions by Lv, Shixian, Wu, Yuchen, Cai, Kaimin, He, Hua, Li, Yongjuan, Lan, Min, Chen, Xuesi, Cheng, Jianjun, Yin, Lichen

“…Polymeric micelles are extensively used for the delivery of hydrophobic drugs, which, however, suffer from unsatisfactory drug loading, colloidal uniformity,…”
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Cisplatin crosslinked pH-sensitive nanoparticles for efficient delivery of doxorubicin by Li, Mingqiang, Tang, Zhaohui, Lv, Shixian, Song, Wantong, Hong, Hua, Jing, Xiabin, Zhang, Yuanyuan, Chen, Xuesi

“…Abstract pH responsive cisplatin prodrug crosslinked polysaccharide-based nanoparticles were developed from succinic acid decorated dextran (Dex-SA) for active…”
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Development of D-melittin polymeric nanoparticles for anti-cancer treatment by Lv, Shixian, Sylvestre, Meilyn, Song, Kefan, Pun, Suzie H.

“…Melittin, the primary peptide component of bee venom, is a potent cytolytic anti-cancer peptide with established anti-tumor activity. However, practical…”
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Well-defined polymer-drug conjugate engineered with redox and pH-sensitive release mechanism for efficient delivery of paclitaxel by Lv, Shixian, Tang, Zhaohui, Zhang, Dawei, Song, Wantong, Li, Mingqiang, Lin, Jian, Liu, Huaiyu, Chen, Xuesi

“…The synthesis of polymer–drug conjugate (PDC) capable of convenient preparation and controlled release of therapeutic agents is still an urgent requirement in…”
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