Search Results - "Lv, Qiaoli"
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A Novel Inflammatory lncRNAs Prognostic Signature for Predicting the Prognosis of Low-Grade Glioma Patients
Published in Frontiers in genetics (02-08-2021)“…Background As immunotherapy has received attention as new treatments for brain cancer, the role of inflammation in the process of glioma is of particular…”
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2
Long non-coding RNA DDX11-AS1 promotes the proliferation and migration of glioma cells by combining with HNRNPC
Published in Molecular therapy. Nucleic acids (14-06-2022)“…Glioma is a malignant tumor of the central nervous system with complex pathogenesis, difficult operation, and a high postoperative recurrence rate. At present,…”
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High Expression of Hyaluronan-Mediated Motility Receptor Predicts Adverse Outcomes: A Potential Therapeutic Target for Head and Neck Squamous Cell Carcinoma
Published in Frontiers in oncology (08-03-2021)“…Several studies have shown that the hyaluronan-mediated motility receptor (HMMR) is overexpressed in various cancers and could be a potential prognostic…”
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4
Synthesis and Molecular Simulation Studies of Mandelic Acid Peptidomimetic Derivatives as Aminopeptidase N Inhibitors
Published in Current computer-aided drug design (01-01-2021)“…The aminopeptidase N (APN) over-expressed in tumor cells plays a critical role in angiogenesis which makes the development of APN inhibitors an attractive…”
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5
Interferon gamma-related gene signature based on anti-tumor immunity predicts glioma patient prognosis
Published in Frontiers in genetics (13-01-2023)“…Glioma is the most common primary tumor of the central nervous system. The conventional glioma treatment strategies include surgical excision and chemo- and…”
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A Signature of N6-methyladenosine Regulator-Related Genes Predicts Prognoses and Immune Responses for Head and Neck Squamous Cell Carcinoma
Published in Frontiers in immunology (03-02-2022)“…This study aimed to construct a signature of N 6 -methyladenosine (m6A) regulator-related genes that could be used for the prognosis of head and neck squamous…”
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NRF2 signaling plays an essential role in cancer progression through the NRF2-GPX2-NOTCH3 axis in head and neck squamous cell carcinoma
Published in Oncogenesis (New York, NY) (27-09-2024)“…The activation of nuclear factor erythroid 2–related factor 2 (NRF2) has been observed in various cancers. Yet its exact contribution to the development of…”
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Abnormal Cellular Populations Shape Thymic Epithelial Tumor Heterogeneity and Anti‐Tumor by Blocking Metabolic Interactions in Organoids
Published in Advanced science (01-11-2024)“…A variety of abnormal epithelial cells and immature and mature immune cells in thymic epithelial tumors (TETs) affect histopathological features, the degree of…”
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High Expression of C1ORF112 Predicts a Poor Outcome: A Potential Target for the Treatment of Low-Grade Gliomas
Published in Frontiers in genetics (22-11-2021)“…Background: Glioma is the most common primary tumor of the central nervous system and is associated with poor overall survival, creating an urgent need to…”
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10
Identification of hub methylated‐CpG sites and associated genes in oral squamous cell carcinoma
Published in Cancer medicine (Malden, MA) (01-05-2020)“…To improve personalized diagnosis and prognosis for oral squamous cell carcinoma (OSCC) by identification of hub methylated‐CpG sites and associated genes,…”
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Fused in silico and bioactivity evaluation method for drug discovery: T001-10027877 was identified as an antiproliferative agent that targets EGFRT790M/C797S/L858R and EGFRT790M/L858R
Published in BMC chemistry (27-08-2024)“…Background Facing the significant challenge of overcoming drug resistance in cancer treatment, particularly resistance caused by mutations in epidermal growth…”
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Synthesis and antiproliferative assay of 1,3,4-oxadiazole and 1,2,4-triazole derivatives in cancer cells
Published in Drug Discoveries & Therapeutics (01-04-2013)“…A series of new 1,3,4-oxadiazole and 1,2,4-triazole derivatives were synthesized. The structures were confirmed by IR, 1H-NMR, and MS. The compounds were…”
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The effect of m6A methyltransferase METTL3 mediated TMEM30A regulation on tumor energy metabolism and cisplatin anti-tumor activity in oral squamous cell carcinoma
Published in Life sciences (1973) (01-12-2024)“…Cisplatin (CDDP) is still one of the most commonly used first-line treatments for advanced and recurrent oral squamous cell carcinoma (OSCC) patients in…”
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14
Research progress and development strategy of PI3K inhibitors for breast cancer treatment: A review (2016-present)
Published in Bioorganic chemistry (01-12-2024)“…PI3K/mTOR inhibitors are effective drugs for breast cancer. In this paper, we review the mechanism of action of PI3K/AKT/mTOR inhibitors, as well as the…”
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Nutritional Status and Incidence of Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients Treated with Chemoradiotherapy
Published in Nutrition and cancer (2024)“…Malnutrition is prevalent among patients with nasopharyngeal carcinoma undergoing radiotherapy. This study examined the nutritional status and incidence of…”
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Novel quinazoline-based dual EGFR/c-Met inhibitors overcoming drug resistance for the treatment of NSCLC: Design, synthesis and anti-tumor activity
Published in Bioorganic chemistry (01-01-2024)“…Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) have demonstrated the ability to impede tumor cell proliferation by suppressing EGFR…”
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17
Decapping enzyme 2 is a novel immune-related biomarker that predicts poor prognosis in glioma
Published in Biotechnology & genetic engineering reviews (01-11-2024)“…This study analyzed sequencing and clinical data from the Cancer Genome Atlas (TCGA) and gene expression synthesis, and used Chinese glioma Genome Atlas (CGGA)…”
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18
A Signature of N 6 -methyladenosine Regulator-Related Genes Predicts Prognoses and Immune Responses for Head and Neck Squamous Cell Carcinoma
Published in Frontiers in immunology (03-02-2022)“…This study aimed to construct a signature of N -methyladenosine (m6A) regulator-related genes that could be used for the prognosis of head and neck squamous…”
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19
Comprehensive study of clinicopathological and immune cell infiltration and lactate dehydrogenase expression in patients with thymic epithelial tumours
Published in International immunopharmacology (05-01-2024)“…Lactate dehydrogenase (LDH) has emerged as a promising biomarker for cancer. However, the current understanding of LDH and circulating LDH expression in thymic…”
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20
Lnc GNG12-AS1 knockdown suppresses glioma progression through the AKT/GSK-3β/β-catenin pathway
Published in Bioscience reports (28-08-2020)“…Long non-coding RNAs (lncRNAs) are increasingly being regarded as regulators of glioma development. Notably, some studies report that GNG12-AS1 plays important…”
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